GB1516793A - 1,4-dihydropyridine-3,5-dicarboxylic acid diester derivative several processes for its preparation and its use as a coronary therapeutic agent - Google Patents
1,4-dihydropyridine-3,5-dicarboxylic acid diester derivative several processes for its preparation and its use as a coronary therapeutic agentInfo
- Publication number
- GB1516793A GB1516793A GB45501/76A GB4550176A GB1516793A GB 1516793 A GB1516793 A GB 1516793A GB 45501/76 A GB45501/76 A GB 45501/76A GB 4550176 A GB4550176 A GB 4550176A GB 1516793 A GB1516793 A GB 1516793A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dihydropyridine
- preparation
- therapeutic agent
- dicarboxylic acid
- acid diester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2549568A DE2549568C3 (de) | 1975-11-05 | 1975-11-05 | 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1516793A true GB1516793A (en) | 1978-07-05 |
Family
ID=5960951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB45501/76A Expired GB1516793A (en) | 1975-11-05 | 1976-11-02 | 1,4-dihydropyridine-3,5-dicarboxylic acid diester derivative several processes for its preparation and its use as a coronary therapeutic agent |
Country Status (27)
Country | Link |
---|---|
JP (1) | JPS5259161A (xx) |
AT (1) | AT352129B (xx) |
AU (1) | AU498964B2 (xx) |
BE (1) | BE847968A (xx) |
BG (6) | BG24804A3 (xx) |
CA (1) | CA1085406A (xx) |
CH (2) | CH623038A5 (xx) |
CS (1) | CS200499B2 (xx) |
DE (1) | DE2549568C3 (xx) |
DK (1) | DK146762C (xx) |
ES (2) | ES452986A1 (xx) |
FI (1) | FI60704C (xx) |
FR (1) | FR2330395A1 (xx) |
GB (1) | GB1516793A (xx) |
GR (1) | GR61241B (xx) |
HK (1) | HK12681A (xx) |
IE (1) | IE43984B1 (xx) |
IL (1) | IL50817A (xx) |
LU (2) | LU88275I2 (xx) |
NL (2) | NL175915C (xx) |
NO (1) | NO145574C (xx) |
NZ (1) | NZ182502A (xx) |
PL (2) | PL106084B1 (xx) |
PT (1) | PT65797B (xx) |
RO (1) | RO70295A (xx) |
SE (1) | SE423542B (xx) |
ZA (1) | ZA766622B (xx) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
JPS55301A (en) * | 1978-02-14 | 1980-01-05 | Yamanouchi Pharmaceut Co Ltd | 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation |
DE3212736A1 (de) * | 1982-04-06 | 1983-10-13 | Bayer Ag, 5090 Leverkusen | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung |
DE3222367A1 (de) * | 1982-06-15 | 1983-12-15 | Bayer Ag, 5090 Leverkusen | Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung |
JPS5982192U (ja) * | 1982-11-27 | 1984-06-02 | エムケ−精工株式会社 | 扉 |
DE3312216A1 (de) * | 1983-04-05 | 1984-10-11 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern |
DE3312283A1 (de) * | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
-
1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/de not_active Expired
-
1976
- 1976-10-22 NO NO763608A patent/NO145574C/no unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/ja active Granted
- 1976-11-01 BG BG7600035344A patent/BG24804A3/xx unknown
- 1976-11-01 BG BG7600035342A patent/BG25079A3/xx unknown
- 1976-11-01 BG BG7600035345A patent/BG24805A3/xx unknown
- 1976-11-01 BG BG7600034575A patent/BG24668A3/xx unknown
- 1976-11-01 BG BG7600035343A patent/BG24803A3/xx unknown
- 1976-11-01 BG BG7600035341A patent/BG25078A3/xx unknown
- 1976-11-02 IL IL50817A patent/IL50817A/xx unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 CH CH1381976A patent/CH623038A5/de not_active IP Right Cessation
- 1976-11-02 CS CS767068A patent/CS200499B2/cs unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/xx unknown
- 1976-11-02 RO RO7688294A patent/RO70295A/ro unknown
- 1976-11-03 FI FI763160A patent/FI60704C/fi not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/pl unknown
- 1976-11-03 PL PL1976201800A patent/PL105940B1/pl unknown
- 1976-11-03 AT AT814276A patent/AT352129B/de not_active IP Right Cessation
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/xx not_active IP Right Cessation
- 1976-11-04 PT PT65797A patent/PT65797B/pt unknown
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 DK DK498476A patent/DK146762C/da not_active IP Right Cessation
- 1976-11-04 ES ES452986A patent/ES452986A1/es not_active Expired
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 ZA ZA766622A patent/ZA766622B/xx unknown
- 1976-11-04 BE BE172063A patent/BE847968A/xx not_active IP Right Cessation
- 1976-11-04 SE SE7612308A patent/SE423542B/xx not_active IP Right Cessation
- 1976-11-04 GR GR52093A patent/GR61241B/el unknown
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-05 FR FR7633488A patent/FR2330395A1/fr active Granted
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
-
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/es not_active Expired
-
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/de not_active IP Right Cessation
-
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/xx unknown
-
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/nl unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
CTFF | Supplementary protection certificate filed |
Free format text: SPC/GB96/042, 960913 |
|
CTFF | Supplementary protection certificate filed |
Free format text: SPC/GB96/042, 960913 |
|
PE20 | Patent expired after termination of 20 years |
Effective date: 19961101 |
|
CTFG | Supplementary protection certificate granted |
Free format text: SPC/GB96/042, 970422, EXPIRES:20011101 |
|
CTFE | Supplementary protection certificate entered into force |
Free format text: SPC/GB96/042, 961102, EXPIRES:20011101 |
|
SPCE | Supplementary protection certificate expired |
Free format text: SPC/GB96/042, 20011101 |