DK146762C - Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester - Google Patents

Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester

Info

Publication number
DK146762C
DK146762C DK498476A DK498476A DK146762C DK 146762 C DK146762 C DK 146762C DK 498476 A DK498476 A DK 498476A DK 498476 A DK498476 A DK 498476A DK 146762 C DK146762 C DK 146762C
Authority
DK
Denmark
Prior art keywords
dihydropyridine
methoxycarbonyl
nitrophenyl
dimethyl
preparation
Prior art date
Application number
DK498476A
Other languages
Danish (da)
English (en)
Other versions
DK146762B (da
DK498476A (da
Inventor
Egbert Wehinger
Friedrich Bossert
Arend Heise
Stanislav Kazda
Kurt Stoepel
Wulf Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK498476A publication Critical patent/DK498476A/da
Publication of DK146762B publication Critical patent/DK146762B/da
Application granted granted Critical
Publication of DK146762C publication Critical patent/DK146762C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK498476A 1975-11-05 1976-11-04 Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester DK146762C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2549568 1975-11-05
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
DK498476A DK498476A (da) 1977-05-06
DK146762B DK146762B (da) 1983-12-27
DK146762C true DK146762C (da) 1984-06-12

Family

ID=5960951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK498476A DK146762C (da) 1975-11-05 1976-11-04 Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester

Country Status (27)

Country Link
JP (1) JPS5259161A (xx)
AT (1) AT352129B (xx)
AU (1) AU498964B2 (xx)
BE (1) BE847968A (xx)
BG (6) BG25078A3 (xx)
CA (1) CA1085406A (xx)
CH (2) CH623038A5 (xx)
CS (1) CS200499B2 (xx)
DE (1) DE2549568C3 (xx)
DK (1) DK146762C (xx)
ES (2) ES452986A1 (xx)
FI (1) FI60704C (xx)
FR (1) FR2330395A1 (xx)
GB (1) GB1516793A (xx)
GR (1) GR61241B (xx)
HK (1) HK12681A (xx)
IE (1) IE43984B1 (xx)
IL (1) IL50817A (xx)
LU (2) LU76133A1 (xx)
NL (2) NL175915C (xx)
NO (1) NO145574C (xx)
NZ (1) NZ182502A (xx)
PL (2) PL105940B1 (xx)
PT (1) PT65797B (xx)
RO (1) RO70295A (xx)
SE (1) SE423542B (xx)
ZA (1) ZA766622B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社 扉
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
IE43984L (en) 1977-05-05
PT65797B (de) 1978-05-12
AU1935876A (en) 1978-05-11
BG24805A3 (en) 1978-05-12
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ATA814276A (de) 1979-02-15
HK12681A (en) 1981-04-10
FI60704C (fi) 1982-03-10
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
NO145574B (no) 1982-01-11
DK146762B (da) 1983-12-27
BG24804A3 (en) 1978-05-12
NO145574C (no) 1982-04-21
FI60704B (fi) 1981-11-30
FI763160A (xx) 1977-05-06
LU76133A1 (xx) 1977-06-02
BE847968A (fr) 1977-05-04
SE423542B (sv) 1982-05-10
BG24668A3 (en) 1978-04-12
IL50817A (en) 1979-07-25
JPS5647185B2 (xx) 1981-11-07
NL930035I1 (nl) 1993-08-02
PL106084B1 (pl) 1979-11-30
CH623038A5 (en) 1981-05-15
PT65797A (de) 1976-12-01
NO763608L (xx) 1977-05-06
GR61241B (en) 1978-10-12
NL175915C (nl) 1985-01-16
FR2330395B1 (xx) 1978-12-22
JPS5259161A (en) 1977-05-16
BG24803A3 (en) 1978-05-12
CA1085406A (en) 1980-09-09
ZA766622B (en) 1977-10-26
IE43984B1 (en) 1981-07-15
BG25078A3 (en) 1978-07-12
NZ182502A (en) 1978-07-28
CS200499B2 (en) 1980-09-15
IL50817A0 (en) 1977-01-31
PL105940B1 (pl) 1979-11-30
DE2549568B2 (de) 1980-08-21
BG25079A3 (en) 1978-07-12
ES452986A1 (es) 1977-12-16
NL7612198A (nl) 1977-05-09
AU498964B2 (en) 1979-03-29
FR2330395A1 (fr) 1977-06-03
DK498476A (da) 1977-05-06
NL930035I2 (nl) 1993-10-01
RO70295A (ro) 1981-08-17
ES463166A1 (es) 1978-07-16
LU88275I2 (xx) 1994-02-03
CH622779A5 (en) 1981-04-30

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PUP Patent expired