DK146626C - Analogifremgangsmaade til fremstilling af 4'-deoxydaunomycin - Google Patents
Analogifremgangsmaade til fremstilling af 4'-deoxydaunomycinInfo
- Publication number
- DK146626C DK146626C DK426076A DK426076A DK146626C DK 146626 C DK146626 C DK 146626C DK 426076 A DK426076 A DK 426076A DK 426076 A DK426076 A DK 426076A DK 146626 C DK146626 C DK 146626C
- Authority
- DK
- Denmark
- Prior art keywords
- unomycine
- deoxyda
- preparation
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK548982A DK147260C (da) | 1975-09-26 | 1982-12-10 | Analogifremgangsmaade til fremstilling af 4'-deoxyadriamycin |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3947175 | 1975-09-26 | ||
| GB39471/75A GB1511559A (en) | 1975-09-26 | 1975-09-26 | Anthracycline glycosides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK426076A DK426076A (da) | 1977-03-27 |
| DK146626B DK146626B (da) | 1983-11-21 |
| DK146626C true DK146626C (da) | 1984-04-30 |
Family
ID=10409731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK426076A DK146626C (da) | 1975-09-26 | 1976-09-22 | Analogifremgangsmaade til fremstilling af 4'-deoxydaunomycin |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4067969A (da) |
| JP (1) | JPS5242869A (da) |
| AT (1) | AT347582B (da) |
| AU (1) | AU504480B2 (da) |
| BE (1) | BE846548A (da) |
| CA (1) | CA1060002A (da) |
| CH (1) | CH606082A5 (da) |
| DE (1) | DE2642837C3 (da) |
| DK (1) | DK146626C (da) |
| FR (1) | FR2325659A1 (da) |
| GB (1) | GB1511559A (da) |
| HK (1) | HK1182A (da) |
| NL (1) | NL174015C (da) |
| SE (2) | SE429655B (da) |
| SU (2) | SU670226A3 (da) |
| ZA (1) | ZA765736B (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1567456A (en) * | 1976-11-16 | 1980-05-14 | Farmaceutici Italia | Daunomycin derivatives |
| GB1550879A (en) * | 1976-12-22 | 1979-08-22 | Farmaceutici Italia | Antitumour glycosides |
| US4362720A (en) * | 1977-04-14 | 1982-12-07 | Chembiomed Ltd. | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals |
| GB1573037A (en) * | 1977-05-05 | 1980-08-13 | Farmaceutici Italia | Anthracyclines |
| GB1573036A (en) * | 1977-05-05 | 1980-08-13 | Farmaceutici Italia | Anthracyclines |
| US4201773A (en) * | 1978-07-26 | 1980-05-06 | The United States Of America As Represented By The Department Of Health, Education And Welfare | 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone |
| US4259476A (en) * | 1979-04-02 | 1981-03-31 | Kende Andrew S | Novel heterocyclic anthracycline compounds |
| ATE1101T1 (de) * | 1979-09-01 | 1982-06-15 | Farmitalia Carlo Erba S.P.A. | Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzung. |
| ZA814722B (en) * | 1980-07-18 | 1982-07-28 | Hoffmann La Roche | Novel anthracycline glycosides |
| CA1174669A (en) * | 1980-07-18 | 1984-09-18 | Michael J. Broadhurst | Anthracycline glycosides |
| US4345070A (en) * | 1980-09-29 | 1982-08-17 | Farmitalia Carlo Erba S.P.A. | Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin |
| US4393052A (en) * | 1980-11-01 | 1983-07-12 | Farmitalia Carlo Erba S.P.A. | Antitumor anthracycline glycosides, their preparation, intermediates therefor, and compositions and use thereof |
| ATE8401T1 (de) * | 1980-11-01 | 1984-07-15 | Farmitalia Carlo Erba S.P.A. | Anthracyclin-glycoside, verfahren zu ihrer herstellung, zwischenprodukte und ihre herstellung und arzneimittel. |
| JPS57142981A (en) * | 1981-01-21 | 1982-09-03 | Erba Carlo Spa | Anthracycline glycoside, manufacture and tumor generation inhibiting drug containing same |
| DE3200809C2 (de) * | 1981-01-21 | 1986-08-28 | Farmitalia Carlo Erba S.p.A., Mailand/Milano | 4'-Desoxy-3'-epi-daunorubicin und -doxorubicin, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4325947A (en) * | 1981-05-12 | 1982-04-20 | Farmitalia Carlo Erba S.P.A. | 4-Demethoxy-4'-deoxydoxorubicin |
| DE3317702A1 (de) * | 1982-05-24 | 1983-11-24 | Farmitalia Carlo Erba S.p.A., 20159 Milano | Anthracyclinglykoside, verfahren zu deren herstellung und arzneimittel, welche diese enthalten |
| US4562177A (en) * | 1982-08-17 | 1985-12-31 | The Ohio State University Research Foundation | 3'-Amino-2' halo-anthracycline antibiotics |
| US4514561A (en) * | 1983-04-15 | 1985-04-30 | Research Corporation | Process for preparing α-L N-acetyl daunosaminide |
| DE3500023A1 (de) * | 1985-01-02 | 1986-07-10 | Farmitalia Carlo Erba S.p.A., Mailand/Milano | 4'-desoxyanthracyclinester |
| GB2169285A (en) * | 1985-01-05 | 1986-07-09 | Erba Farmitalia | 4'-Deoxydoxorubicin-14-esters |
| GB8519452D0 (en) * | 1985-08-02 | 1985-09-11 | Erba Farmitalia | Injectable solutions |
| US5124317A (en) * | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.P.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
| GB8708927D0 (en) * | 1987-04-14 | 1987-05-20 | Erba Farmitalia | Chiral synthesis of anthracyclines |
| NZ224252A (en) | 1987-04-21 | 1991-09-25 | Erba Carlo Spa | An anthracycline glycoside and its preparation |
| GB2212154B (en) * | 1987-11-10 | 1991-03-27 | Erba Carlo Spa | New 4-demethoxy anthracycline derivatives |
| JPH03502327A (ja) * | 1988-01-19 | 1991-05-30 | ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム | ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法 |
| GB8803076D0 (en) * | 1988-02-10 | 1988-03-09 | Erba Carlo Spa | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
| AU4752190A (en) * | 1988-12-28 | 1990-08-01 | Board Of Regents, The University Of Texas System | 3'-deamino analogs of esorubicin and methods for their use |
| US5948896A (en) * | 1997-08-13 | 1999-09-07 | Gem Pharmaceuticals | Processes for preparing 13-deoxy anthracycline derivatives |
| US5942605A (en) * | 1998-03-03 | 1999-08-24 | Gem Pharmaceuticals, Inc. | 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3803124A (en) * | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
| DE1792346C3 (de) * | 1968-08-22 | 1980-10-23 | Rotta Research Laboratorium S.P.A., San Fruttuoso Di Monza, Mailand (Italien) | Pharmazeutisches Präparat für die Behandlung von degenerativen Gelenkerkrankungen |
| FR2183710A1 (en) * | 1972-05-06 | 1973-12-21 | Farmaceutici Italia | Daunomycin (hydrochloride) prepn - by reaction of daunomycinone with daunosamines, useful as antitumour agent and anti-leucemic |
| US4020270A (en) * | 1974-05-02 | 1977-04-26 | Societa' Farmaceutici Italia S.P.A. | L-lyxohex-1-enopyranose derivative |
-
1975
- 1975-09-26 GB GB39471/75A patent/GB1511559A/en not_active Expired
-
1976
- 1976-09-13 NL NLAANVRAGE7610139,A patent/NL174015C/xx not_active IP Right Cessation
- 1976-09-13 US US05/722,689 patent/US4067969A/en not_active Expired - Lifetime
- 1976-09-22 DK DK426076A patent/DK146626C/da not_active IP Right Cessation
- 1976-09-22 AU AU18025/76A patent/AU504480B2/en not_active Expired
- 1976-09-23 AT AT707276A patent/AT347582B/de not_active IP Right Cessation
- 1976-09-23 SE SE7610564A patent/SE429655B/xx not_active IP Right Cessation
- 1976-09-23 FR FR7628582A patent/FR2325659A1/fr active Granted
- 1976-09-23 CA CA261,920A patent/CA1060002A/en not_active Expired
- 1976-09-23 DE DE2642837A patent/DE2642837C3/de not_active Expired
- 1976-09-24 BE BE170901A patent/BE846548A/xx not_active IP Right Cessation
- 1976-09-24 ZA ZA765736A patent/ZA765736B/xx unknown
- 1976-09-24 SU SU762403408A patent/SU670226A3/ru active
- 1976-09-24 JP JP51115356A patent/JPS5242869A/ja active Granted
- 1976-09-24 CH CH1215876A patent/CH606082A5/xx not_active IP Right Cessation
-
1977
- 1977-09-22 SU SU772523451A patent/SU730310A3/ru active
-
1980
- 1980-02-29 SE SE8001616A patent/SE435514B/sv not_active IP Right Cessation
-
1982
- 1982-01-14 HK HK11/82A patent/HK1182A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU504480B2 (en) | 1979-10-18 |
| SE8001616L (sv) | 1980-02-29 |
| SE7610564L (sv) | 1977-03-27 |
| GB1511559A (en) | 1978-05-24 |
| HK1182A (en) | 1982-01-22 |
| SU670226A3 (ru) | 1979-06-25 |
| DE2642837A1 (de) | 1977-04-07 |
| SE429655B (sv) | 1983-09-19 |
| JPS6123189B2 (da) | 1986-06-04 |
| AT347582B (de) | 1979-01-10 |
| CH606082A5 (da) | 1978-10-13 |
| FR2325659B1 (da) | 1982-08-20 |
| NL174015B (nl) | 1983-11-16 |
| ZA765736B (en) | 1977-11-30 |
| JPS5242869A (en) | 1977-04-04 |
| DK426076A (da) | 1977-03-27 |
| DE2642837B2 (de) | 1982-01-07 |
| DK146626B (da) | 1983-11-21 |
| FR2325659A1 (fr) | 1977-04-22 |
| NL174015C (nl) | 1984-04-16 |
| CA1060002A (en) | 1979-08-07 |
| SE435514B (sv) | 1984-10-01 |
| DE2642837C3 (de) | 1982-08-12 |
| AU1802576A (en) | 1978-04-06 |
| NL7610139A (nl) | 1977-03-29 |
| SU730310A3 (ru) | 1980-04-25 |
| US4067969A (en) | 1978-01-10 |
| ATA707276A (de) | 1978-05-15 |
| BE846548A (fr) | 1977-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |