DK149773C - Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater - Google Patents

Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater

Info

Publication number
DK149773C
DK149773C DK520679A DK520679A DK149773C DK 149773 C DK149773 C DK 149773C DK 520679 A DK520679 A DK 520679A DK 520679 A DK520679 A DK 520679A DK 149773 C DK149773 C DK 149773C
Authority
DK
Denmark
Prior art keywords
preparation
acid derivatives
analogy procedure
quinolincarboxylic acid
quinolincarboxylic
Prior art date
Application number
DK520679A
Other languages
English (en)
Other versions
DK149773B (da
DK520679A (da
Inventor
Francois Clemence
Roger Deraedt
Andre Allais
Odile Le Martret
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK520679A publication Critical patent/DK520679A/da
Publication of DK149773B publication Critical patent/DK149773B/da
Application granted granted Critical
Publication of DK149773C publication Critical patent/DK149773C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK520679A 1978-12-08 1979-12-07 Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater DK149773C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7834592A FR2443467A1 (fr) 1978-12-08 1978-12-08 Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR7834592 1978-12-08

Publications (3)

Publication Number Publication Date
DK520679A DK520679A (da) 1980-06-09
DK149773B DK149773B (da) 1986-09-29
DK149773C true DK149773C (da) 1987-03-23

Family

ID=9215841

Family Applications (1)

Application Number Title Priority Date Filing Date
DK520679A DK149773C (da) 1978-12-08 1979-12-07 Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater

Country Status (12)

Country Link
US (1) US4299831A (da)
EP (2) EP0012639B1 (da)
JP (1) JPS5581878A (da)
AU (1) AU531501B2 (da)
CA (1) CA1137985A (da)
DE (1) DE2966142D1 (da)
DK (1) DK149773C (da)
ES (1) ES8103045A1 (da)
FR (1) FR2443467A1 (da)
HU (1) HU182570B (da)
IE (1) IE49875B1 (da)
ZA (1) ZA796244B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482596A1 (fr) * 1980-05-19 1981-11-20 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament
HU190796B (en) * 1981-06-12 1986-11-28 Roussel Uclaf,Fr Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
FR2509728A1 (fr) * 1981-07-17 1983-01-21 Roussel Uclaf Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2537139B2 (fr) * 1982-03-15 1985-09-20 Roussel Uclaf Nouveau derive de la n-dihydrothiazolyl 3-quinoleine carboxamide, procede de preparation, application a titre de medicament et compositions le renfermant
FR2532314B1 (fr) * 1982-08-25 1985-07-19 Roussel Uclaf Nouveau procede de preparation de derives de l'acide 3-quinoleine carboxylique, nouveaux derives halogenes de l'acide 3-quinoleine carboxylique, leur application comme medicaments, les compositions pharmaceutiques les renfermant et les intermediaires nouveaux obtenus
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
FR2636329B2 (fr) * 1987-03-13 1990-11-02 Roussel Uclaf Nouveaux derives de la pyridine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant
FR2612189B1 (fr) * 1987-03-13 1989-06-23 Roussel Uclaf Nouveaux derives de la pyridine, leur procede de preparation et les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions les renfermant
US4966906A (en) * 1987-11-27 1990-10-30 Hoechst-Roussel Pharmaceuticals Inc. 1-aryl-3-isoquinolinecarboxamides
US5028707A (en) * 1989-11-20 1991-07-02 Board Of Regents, University Of Texas 4-hydroxyquinaldic acid derivatives
GB9108547D0 (en) * 1991-04-22 1991-06-05 Fujisawa Pharmaceutical Co Quinoline derivatives
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
EP1671945A4 (en) 2003-10-10 2007-08-22 Toyo Kasei Kogyo Co Ltd PROCESS FOR PRODUCING 1-ARYL-5- (TRIFLUOROMETHYL) -1H-TETRAZOLES
BR122018075478B8 (pt) * 2004-06-24 2023-10-31 Vertex Pharma moduladores de transportadores de cassete de ligação de atp
HUE049976T2 (hu) 2005-12-28 2020-11-30 Vertex Pharma N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói
SG10201504084QA (en) 2009-03-20 2015-06-29 Vertex Pharma Process for making modulators of cystic fibrosis transmembrane conductance regulator
CN109966264A (zh) 2012-02-27 2019-07-05 沃泰克斯药物股份有限公司 药物组合物及其施用
CN107250113B (zh) 2014-10-07 2019-03-29 弗特克斯药品有限公司 囊性纤维化跨膜传导调节蛋白的调节剂的共晶

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044138A (en) * 1972-10-21 1977-08-23 John Wyeth & Brother Limited Pharmaceutical compositions containing 5,6,7,8-tetrahydroquinoline derivatives and related compounds
FR2281761A1 (fr) * 1974-08-13 1976-03-12 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2324304A2 (fr) * 1975-09-22 1977-04-15 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
JPS5291876A (en) * 1976-01-27 1977-08-02 Roussel Uclaf Novel derivatives of 33quinolinecarboxylic acid and medicine comprising same
FR2340735A1 (fr) * 1976-02-11 1977-09-09 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE2966142D1 (en) 1983-10-13
IE49875B1 (en) 1986-01-08
ES486671A0 (es) 1981-02-16
EP0049555B1 (fr) 1984-02-22
ZA796244B (en) 1980-11-26
EP0012639B1 (fr) 1983-09-07
JPS5581878A (en) 1980-06-20
EP0012639A3 (en) 1980-11-12
EP0049555A1 (fr) 1982-04-14
US4299831A (en) 1981-11-10
EP0012639A2 (fr) 1980-06-25
IE792367L (en) 1980-06-08
ES8103045A1 (es) 1981-02-16
HU182570B (en) 1984-02-28
AU5358579A (en) 1980-06-12
DK149773B (da) 1986-09-29
JPS6330914B2 (da) 1988-06-21
FR2443467B1 (da) 1981-08-14
CA1137985A (fr) 1982-12-21
AU531501B2 (en) 1983-08-25
FR2443467A1 (fr) 1980-07-04
DK520679A (da) 1980-06-09

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