FR2330395A1 - Ester isobutylique de l'acide 2,6-dimethyl-3-methoxycarbonyl-4-(2'nitrophenyl)-1,4-dihydropyridine-5-carboxylique, son procede de preparation et medicament a usage coronarien le contenant - Google Patents

Ester isobutylique de l'acide 2,6-dimethyl-3-methoxycarbonyl-4-(2'nitrophenyl)-1,4-dihydropyridine-5-carboxylique, son procede de preparation et medicament a usage coronarien le contenant

Info

Publication number
FR2330395A1
FR2330395A1 FR7633488A FR7633488A FR2330395A1 FR 2330395 A1 FR2330395 A1 FR 2330395A1 FR 7633488 A FR7633488 A FR 7633488A FR 7633488 A FR7633488 A FR 7633488A FR 2330395 A1 FR2330395 A1 FR 2330395A1
Authority
FR
France
Prior art keywords
dihydropyridine
methoxycarbonyl
nitrophenyl
coronary
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7633488A
Other languages
English (en)
Other versions
FR2330395B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of FR2330395A1 publication Critical patent/FR2330395A1/fr
Application granted granted Critical
Publication of FR2330395B1 publication Critical patent/FR2330395B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7633488A 1975-11-05 1976-11-05 Ester isobutylique de l'acide 2,6-dimethyl-3-methoxycarbonyl-4-(2'nitrophenyl)-1,4-dihydropyridine-5-carboxylique, son procede de preparation et medicament a usage coronarien le contenant Granted FR2330395A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
FR2330395A1 true FR2330395A1 (fr) 1977-06-03
FR2330395B1 FR2330395B1 (fr) 1978-12-22

Family

ID=5960951

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7633488A Granted FR2330395A1 (fr) 1975-11-05 1976-11-05 Ester isobutylique de l'acide 2,6-dimethyl-3-methoxycarbonyl-4-(2'nitrophenyl)-1,4-dihydropyridine-5-carboxylique, son procede de preparation et medicament a usage coronarien le contenant

Country Status (27)

Country Link
JP (1) JPS5259161A (fr)
AT (1) AT352129B (fr)
AU (1) AU498964B2 (fr)
BE (1) BE847968A (fr)
BG (6) BG25078A3 (fr)
CA (1) CA1085406A (fr)
CH (2) CH623038A5 (fr)
CS (1) CS200499B2 (fr)
DE (1) DE2549568C3 (fr)
DK (1) DK146762C (fr)
ES (2) ES452986A1 (fr)
FI (1) FI60704C (fr)
FR (1) FR2330395A1 (fr)
GB (1) GB1516793A (fr)
GR (1) GR61241B (fr)
HK (1) HK12681A (fr)
IE (1) IE43984B1 (fr)
IL (1) IL50817A (fr)
LU (2) LU88275I2 (fr)
NL (2) NL175915C (fr)
NO (1) NO145574C (fr)
NZ (1) NZ182502A (fr)
PL (2) PL106084B1 (fr)
PT (1) PT65797B (fr)
RO (1) RO70295A (fr)
SE (1) SE423542B (fr)
ZA (1) ZA766622B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2370744A1 (fr) * 1976-11-12 1978-06-09 Boehringer Mannheim Gmbh Nouveaux derives d'aminopropanol, procede pour leur preparation et medicaments contenant ces composes
FR2524314A1 (fr) * 1982-04-06 1983-10-07 Bayer Ag Medicament a action salidiuretique, contenant des dihydropyridines
FR2528425A1 (fr) * 1982-06-15 1983-12-16 Bayer Ag 1,4-dihydropyridines et composition pharmaceutique les contenant

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2370744A1 (fr) * 1976-11-12 1978-06-09 Boehringer Mannheim Gmbh Nouveaux derives d'aminopropanol, procede pour leur preparation et medicaments contenant ces composes
FR2524314A1 (fr) * 1982-04-06 1983-10-07 Bayer Ag Medicament a action salidiuretique, contenant des dihydropyridines
FR2528425A1 (fr) * 1982-06-15 1983-12-16 Bayer Ag 1,4-dihydropyridines et composition pharmaceutique les contenant

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
DK146762C (da) 1984-06-12
CH623038A5 (en) 1981-05-15
NL930035I2 (nl) 1993-10-01
SE423542B (sv) 1982-05-10
DE2549568B2 (de) 1980-08-21
BG25078A3 (en) 1978-07-12
BG24805A3 (en) 1978-05-12
AU498964B2 (en) 1979-03-29
ES452986A1 (es) 1977-12-16
FI60704B (fi) 1981-11-30
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
BG25079A3 (en) 1978-07-12
LU76133A1 (fr) 1977-06-02
CH622779A5 (en) 1981-04-30
JPS5259161A (en) 1977-05-16
BG24804A3 (en) 1978-05-12
CS200499B2 (en) 1980-09-15
PT65797B (de) 1978-05-12
BG24803A3 (en) 1978-05-12
PL105940B1 (pl) 1979-11-30
AU1935876A (en) 1978-05-11
NO145574C (no) 1982-04-21
NZ182502A (en) 1978-07-28
DK146762B (da) 1983-12-27
BG24668A3 (en) 1978-04-12
IE43984B1 (en) 1981-07-15
LU88275I2 (fr) 1994-02-03
CA1085406A (fr) 1980-09-09
GR61241B (en) 1978-10-12
NL930035I1 (nl) 1993-08-02
DK498476A (da) 1977-05-06
NL7612198A (nl) 1977-05-09
ZA766622B (en) 1977-10-26
PL106084B1 (pl) 1979-11-30
FR2330395B1 (fr) 1978-12-22
PT65797A (de) 1976-12-01
NO763608L (fr) 1977-05-06
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ES463166A1 (es) 1978-07-16
NO145574B (no) 1982-01-11
HK12681A (en) 1981-04-10
BE847968A (fr) 1977-05-04
IL50817A0 (en) 1977-01-31
ATA814276A (de) 1979-02-15
IE43984L (en) 1977-05-05
NL175915C (nl) 1985-01-16
IL50817A (en) 1979-07-25
JPS5647185B2 (fr) 1981-11-07
RO70295A (fr) 1981-08-17
FI60704C (fi) 1982-03-10
FI763160A (fr) 1977-05-06

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