BG25079A3 - A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid - Google Patents

A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid

Info

Publication number
BG25079A3
BG25079A3 BG035342A BG3534276A BG25079A3 BG 25079 A3 BG25079 A3 BG 25079A3 BG 035342 A BG035342 A BG 035342A BG 3534276 A BG3534276 A BG 3534276A BG 25079 A3 BG25079 A3 BG 25079A3
Authority
BG
Bulgaria
Prior art keywords
dichidropiridin
metoxycarbonyl
nitrophenyl
dimethyl
obtaining
Prior art date
Application number
BG035342A
Other languages
Bulgarian (bg)
English (en)
Inventor
Egbert Wehinger
Friedrich Bossert
Arend Heise
Stanislav Karda
Kurt Stoepel
Wulf Vater
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG25079A3 publication Critical patent/BG25079A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG035342A 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid BG25079A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG25079A3 true BG25079A3 (en) 1978-07-12

Family

ID=5960951

Family Applications (6)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Family Applications Before (3)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Country Status (27)

Country Link
JP (1) JPS5259161A (xx)
AT (1) AT352129B (xx)
AU (1) AU498964B2 (xx)
BE (1) BE847968A (xx)
BG (6) BG25078A3 (xx)
CA (1) CA1085406A (xx)
CH (2) CH623038A5 (xx)
CS (1) CS200499B2 (xx)
DE (1) DE2549568C3 (xx)
DK (1) DK146762C (xx)
ES (2) ES452986A1 (xx)
FI (1) FI60704C (xx)
FR (1) FR2330395A1 (xx)
GB (1) GB1516793A (xx)
GR (1) GR61241B (xx)
HK (1) HK12681A (xx)
IE (1) IE43984B1 (xx)
IL (1) IL50817A (xx)
LU (2) LU76133A1 (xx)
NL (2) NL175915C (xx)
NO (1) NO145574C (xx)
NZ (1) NZ182502A (xx)
PL (2) PL105940B1 (xx)
PT (1) PT65797B (xx)
RO (1) RO70295A (xx)
SE (1) SE423542B (xx)
ZA (1) ZA766622B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
IE43984L (en) 1977-05-05
PT65797B (de) 1978-05-12
AU1935876A (en) 1978-05-11
BG24805A3 (en) 1978-05-12
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ATA814276A (de) 1979-02-15
HK12681A (en) 1981-04-10
FI60704C (fi) 1982-03-10
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
NO145574B (no) 1982-01-11
DK146762B (da) 1983-12-27
BG24804A3 (en) 1978-05-12
NO145574C (no) 1982-04-21
FI60704B (fi) 1981-11-30
FI763160A (xx) 1977-05-06
LU76133A1 (xx) 1977-06-02
BE847968A (fr) 1977-05-04
SE423542B (sv) 1982-05-10
BG24668A3 (en) 1978-04-12
IL50817A (en) 1979-07-25
JPS5647185B2 (xx) 1981-11-07
NL930035I1 (nl) 1993-08-02
PL106084B1 (pl) 1979-11-30
CH623038A5 (en) 1981-05-15
PT65797A (de) 1976-12-01
NO763608L (xx) 1977-05-06
GR61241B (en) 1978-10-12
NL175915C (nl) 1985-01-16
FR2330395B1 (xx) 1978-12-22
JPS5259161A (en) 1977-05-16
BG24803A3 (en) 1978-05-12
CA1085406A (en) 1980-09-09
ZA766622B (en) 1977-10-26
IE43984B1 (en) 1981-07-15
BG25078A3 (en) 1978-07-12
NZ182502A (en) 1978-07-28
CS200499B2 (en) 1980-09-15
IL50817A0 (en) 1977-01-31
PL105940B1 (pl) 1979-11-30
DE2549568B2 (de) 1980-08-21
ES452986A1 (es) 1977-12-16
DK146762C (da) 1984-06-12
NL7612198A (nl) 1977-05-09
AU498964B2 (en) 1979-03-29
FR2330395A1 (fr) 1977-06-03
DK498476A (da) 1977-05-06
NL930035I2 (nl) 1993-10-01
RO70295A (ro) 1981-08-17
ES463166A1 (es) 1978-07-16
LU88275I2 (xx) 1994-02-03
CH622779A5 (en) 1981-04-30

Similar Documents

Publication Publication Date Title
RO72521A (ro) Procedeu de preparare a n-fenil-n'-benzilureelor
YU40004B (en) Praocess for preparing n-substituted esters of 9,10-dihydrlysergic acid
IL52023A (en) Process for the preparation of di-n-propyl-acetic acid and salts thereof
BG25074A3 (en) A method of obtaining substituted perhaloalkylamidines
BG25079A3 (en) A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
GR61620B (en) Preparation process of pyrazol-1-yl-phenyloxic acids
YU126276A (en) Process for preparing new propargyl-2-phenylamino-imidazolines-(2) and acid addition salts thereof
HU173394B (hu) Sposob poluchenija proizvodnykh 7-metoksi-7-skobka-geterociklichnye-acilamido-skobka zakryta-acetamido-cef-3-em-4-karbonovykh kislot
PT67013B (en) Process for the preparation of 2-isopropyl-phenyl-3-butenoic acid benzyl esters
JPS5495573A (en) Manufacture of 3*44methylene dioxymandelic acid
CS193588B2 (en) Method of producing 7 beta-/d-2-amino-2-/r'sulphonylaminophenyl/acetylymino/-2-r-cephem-4-carboxylic acids
JPS52122377A (en) Method of preparation of 22chloronicotinic acid
PH12580A (en) An improved process for the preparation of 6-amino-penicillanic acid
JPS52100451A (en) Process for manufacture of 2*22dimethyll33 *2*22dichlorovinyl**cyclopropanee11carboxylic acid
BG25223A3 (en) A method of obtaining 2,6,6-threemethyl-2-cyanomethyl-tetrahydropiran
CS189766B2 (en) Method of preparing perpropionic acid
CS183844B2 (en) Mode of manufacture of new o-ethyl-o-/1,6-dihydro-1-hydroxymethyl-6-oxo-3-pyridazinyl/of ester of thionobenzenphosphon acid
BG25212A3 (en) A method of obtaining substituted arylalcylamines
BG24945A3 (en) A method of obtaining pentahalogenphenyl-malonic acid esters
JPS5490181A (en) Two step manufacture of 2*66pyridinee dicarboxylic acid
JPS5365843A (en) Process for preparing ester of alkyllsubstituted betaaresorcilic acid
JPS5359689A (en) Production of 77 aminocedhalosporanic acid derivative
JPS5340757A (en) Novel method of preparation of 2*33dichloroo 44*22thenoyl*phenoxyacetic acid
IL52183A0 (en) A method of preparing derivatives of 7-amino-delta3-desacetoxycephalosporanic acid
PT67381B (en) A process for preparing a mixture of 2-ketogulonic and 2-ketogluconic acid or salts of these acids