|
US7090843B1
(en)
†
|
2000-11-28 |
2006-08-15 |
Seattle Genetics, Inc. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
US20040018194A1
(en)
*
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
US20110313230A1
(en)
|
2001-05-11 |
2011-12-22 |
Terrance Grant Johns |
Specific binding proteins and uses thereof
|
|
AU2002363939A1
(en)
*
|
2001-11-20 |
2003-06-10 |
Seattle Genetics, Inc. |
Treatment of immunological disorders using anti-cd30 antibodies
|
|
CA2471645A1
(en)
*
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
CN1638800B
(zh)
|
2002-01-09 |
2014-07-16 |
梅达雷克斯有限责任公司 |
抗cd30的人类单克隆抗体
|
|
US20070148171A1
(en)
*
|
2002-09-27 |
2007-06-28 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
|
SI1545613T1
(sl)
|
2002-07-31 |
2011-11-30 |
Seattle Genetics Inc |
Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni
|
|
KR101438983B1
(ko)
|
2003-11-06 |
2014-09-05 |
시애틀 지네틱스, 인크. |
리간드에 접합될 수 있는 모노메틸발린 화합물
|
|
CA2582016A1
(en)
|
2004-10-01 |
2006-04-13 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
|
US8207303B2
(en)
|
2005-02-18 |
2012-06-26 |
Medarex, Inc. |
Monoclonal antibodies against CD30 lacking in fucosyl residues
|
|
WO2007044616A2
(en)
*
|
2005-10-06 |
2007-04-19 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
|
WO2008025020A2
(en)
*
|
2006-08-25 |
2008-02-28 |
Seattle Genetics, Inc. |
Cd30 binding agents and uses thereof
|
|
EP2176295B1
(en)
|
2007-07-16 |
2014-11-19 |
Genentech, Inc. |
Humanized anti-cd79b antibodies and immunoconjugates and methods of use
|
|
JP5469600B2
(ja)
|
2007-07-16 |
2014-04-16 |
ジェネンテック, インコーポレイテッド |
抗CD79b抗体及びイムノコンジュゲートとその使用方法
|
|
WO2009026274A1
(en)
|
2007-08-22 |
2009-02-26 |
Medarex, Inc. |
Site-specific attachment of drugs or other agents to engineered antibodies with c-terminal extensions
|
|
KR101641345B1
(ko)
|
2007-10-12 |
2016-07-20 |
시애틀 지네틱스, 인크. |
항체-약물 접합체를 이용한 병용 요법
|
|
ES2643239T3
(es)
|
2008-01-31 |
2017-11-21 |
Genentech, Inc. |
Anticuerpos anti-CD79b e inmunoconjugados y métodos de uso
|
|
WO2010027513A2
(en)
|
2008-09-08 |
2010-03-11 |
Psma Development Company, Llc |
Methods for killing psma-expressing, taxane-resistant cancer cells
|
|
US9211319B2
(en)
|
2009-01-09 |
2015-12-15 |
Seattle Genetics, Inc. |
Weekly dosing regimens for anti-CD30 VC-PAB-MMAE antibody drug-conjugates
|
|
KR101224468B1
(ko)
*
|
2009-05-20 |
2013-01-23 |
주식회사 파멥신 |
신규한 형태의 이중표적항체 및 그 용도
|
|
US20110076232A1
(en)
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
|
WO2012054748A2
(en)
|
2010-10-22 |
2012-04-26 |
Seattle Genetics, Inc. |
Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the pi3k-akt mtor pathway
|
|
CA2858806A1
(en)
|
2011-12-23 |
2013-06-27 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
CN117264057A
(zh)
*
|
2012-04-27 |
2023-12-22 |
诺和诺德股份有限公司 |
人cd30配体抗原结合蛋白
|
|
US10132799B2
(en)
|
2012-07-13 |
2018-11-20 |
Innate Pharma |
Screening of conjugated antibodies
|
|
CN104755494B
(zh)
|
2012-10-11 |
2018-09-07 |
第一三共株式会社 |
抗体-药物偶联物
|
|
WO2014061277A1
(ja)
|
2012-10-19 |
2014-04-24 |
第一三共株式会社 |
親水性構造を含むリンカーで結合させた抗体-薬物コンジュゲート
|
|
EP2916872B1
(en)
|
2012-11-09 |
2019-02-27 |
Innate Pharma |
Recognition tags for tgase-mediated conjugation
|
|
EP2922818B1
(en)
|
2012-11-24 |
2018-09-05 |
Hangzhou Dac Biotech Co., Ltd |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
|
WO2014089177A2
(en)
|
2012-12-04 |
2014-06-12 |
Massachusetts Institute Of Technology |
Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
|
|
RU2015129800A
(ru)
|
2012-12-21 |
2017-01-30 |
Биоэллаенс К. В. |
Гидрофильные саморазрушающиеся линкеры и их конъюгаты
|
|
WO2014140300A1
(en)
|
2013-03-15 |
2014-09-18 |
Innate Pharma |
Solid phase tgase-mediated conjugation of antibodies
|
|
TW201945032A
(zh)
|
2013-03-15 |
2019-12-01 |
德商艾伯維德國有限及兩合公司 |
抗-egfr抗體藥物結合物調配物
|
|
AU2014240012A1
(en)
|
2013-03-15 |
2015-09-24 |
Abbvie Inc. |
Antibody drug conjugate (ADC) purification
|
|
JP6433085B2
(ja)
|
2013-04-09 |
2018-12-05 |
ボストン バイオメディカル, インコーポレイテッド |
がんの処置に使用するための2−アセチルナフト[2,3−b]フラン−4,9−ジオン
|
|
EP3010547B1
(en)
|
2013-06-20 |
2021-04-21 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
CN105517577A
(zh)
|
2013-06-21 |
2016-04-20 |
先天制药公司 |
多肽的酶促偶联
|
|
CA3187392A1
(en)
|
2013-10-15 |
2015-04-23 |
Seagen Inc. |
Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
|
|
AU2015210578B2
(en)
|
2014-01-29 |
2020-04-16 |
Jiangsu Hengrui Medicine Co., Ltd. |
Ligand-cytotoxic drug conjugate, preparation method therefor, and uses thereof
|
|
WO2015127685A1
(en)
|
2014-02-28 |
2015-09-03 |
Hangzhou Dac Biotech Co., Ltd |
Charged linkers and their uses for conjugation
|
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
US9950077B2
(en)
|
2014-06-20 |
2018-04-24 |
Bioalliance C.V. |
Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof
|
|
DK3160513T3
(da)
|
2014-06-30 |
2020-04-06 |
Glykos Finland Oy |
Saccharidderivat af en toksisk payload og antistofkonjugater deraf
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
EP3262071B8
(en)
|
2014-09-23 |
2022-05-18 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CN114656573B
(zh)
|
2015-05-30 |
2024-09-27 |
分子模板公司 |
去免疫化的志贺毒素a亚基支架和包含它们的细胞靶向分子
|
|
BR112017026025A2
(pt)
|
2015-06-03 |
2018-08-14 |
Boston Biomedical Inc |
composições que compreendem um inibidor de stemness de câncer e um agente imunoterápico para uso no tratamento de câncer
|
|
CN108026123B
(zh)
|
2015-06-15 |
2021-02-05 |
杭州多禧生物科技有限公司 |
用于偶联的亲水链接体
|
|
CA2991973C
(en)
|
2015-07-12 |
2021-12-07 |
Suzhou M-Conj Biotech Co., Ltd. |
Bridge linkers for conjugation of a cell-binding molecule
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
|
CN116334143A
(zh)
|
2015-11-23 |
2023-06-27 |
诺华股份有限公司 |
优化的慢病毒转移载体及其用途
|
|
CA3009709A1
(en)
|
2015-12-30 |
2017-07-06 |
Novartis Ag |
Immune effector cell therapies with enhanced efficacy
|
|
MX395252B
(es)
|
2016-01-08 |
2025-03-25 |
Altrubio Inc |
Anticuerpos tetravalentes anti ligando-1 de glicoproteina p-selectina (psgl-1) y usos de estos.
|
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
JP7073266B2
(ja)
|
2016-03-25 |
2022-05-23 |
シージェン インコーポレイテッド |
Peg化薬物リンカー及びその中間体を調製するためのプロセス
|
|
US10918627B2
(en)
|
2016-05-11 |
2021-02-16 |
Massachusetts Institute Of Technology |
Convergent and enantioselective total synthesis of Communesin analogs
|
|
CA3042889A1
(en)
|
2016-11-14 |
2018-05-17 |
Millennium Pharmaceuticals, Inc. |
Non-adult human dosing of anti-cd30 antibody-drug conjugates
|
|
KR102345175B1
(ko)
|
2016-11-14 |
2021-12-31 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
WO2018102427A1
(en)
|
2016-11-29 |
2018-06-07 |
Boston Biomedical, Inc. |
Naphthofuran derivatives, preparation, and methods of use thereof
|
|
WO2018111340A1
(en)
|
2016-12-16 |
2018-06-21 |
Novartis Ag |
Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells
|
|
CN106854245A
(zh)
*
|
2016-12-28 |
2017-06-16 |
无锡傲锐东源生物科技有限公司 |
抗cd30蛋白单克隆抗体及其用途
|
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
US20190375815A1
(en)
|
2017-01-31 |
2019-12-12 |
Novartis Ag |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
US20210330801A1
(en)
|
2017-03-02 |
2021-10-28 |
Cadila Healthcare Limited |
Novel protein drug conjugate formulation
|
|
US11730822B2
(en)
|
2017-03-24 |
2023-08-22 |
Seagen Inc. |
Process for the preparation of glucuronide drug-linkers and intermediates thereof
|
|
CA3062656A1
(en)
|
2017-05-17 |
2018-11-22 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
JP2020536916A
(ja)
|
2017-10-11 |
2020-12-17 |
シアトル ジェネティクス,インコーポレイティド |
抗cd30抗体薬物複合体療法の副作用を軽減する方法
|
|
US10640508B2
(en)
|
2017-10-13 |
2020-05-05 |
Massachusetts Institute Of Technology |
Diazene directed modular synthesis of compounds with quaternary carbon centers
|
|
SG11202003177RA
(en)
|
2017-10-25 |
2020-05-28 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
JP2021501800A
(ja)
|
2017-11-01 |
2021-01-21 |
シアトル ジェネティクス,インコーポレイティド |
抗cd30抗体薬物複合体療法の副作用を軽減する方法
|
|
CN117126279A
(zh)
|
2018-03-20 |
2023-11-28 |
鸿运华宁(杭州)生物医药有限公司 |
Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用
|
|
MX2020009842A
(es)
|
2018-03-23 |
2020-10-15 |
Seattle Genetics Inc |
Uso de conjugados de anticuerpo-farmaco que comprenden agentes interruptores de tubulina para tratar tumor solido.
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
TW202519270A
(zh)
|
2018-06-07 |
2025-05-16 |
美商思進公司 |
喜樹鹼結合物
|
|
EP3802825A1
(en)
|
2018-06-08 |
2021-04-14 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020068764A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
Anti-cd30 antibodies and methods of use
|
|
CA3114137A1
(en)
|
2018-09-26 |
2020-04-02 |
Jiangsu Hengrui Medicine Co., Ltd. |
Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof
|
|
KR20210069679A
(ko)
|
2018-10-01 |
2021-06-11 |
씨젠 인크. |
항-cd30 항체 약물 컨쥬게이트 요법을 사용하여 말초 t 세포 림프종을 치료하는 방법
|
|
EP3883610A4
(en)
|
2018-11-20 |
2022-11-02 |
Cornell University |
MACROCYCLIC COMPLEXES OF RADIONUCLIDES AND THEIR USE IN CANCER RADIATION THERAPY
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
JP7483732B2
(ja)
|
2019-02-15 |
2024-05-15 |
ノバルティス アーゲー |
3-(1-オキソ-5-(ピペリジン-4-イル)イソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
ES2982474T3
(es)
|
2019-02-15 |
2024-10-16 |
Novartis Ag |
Derivados de 3-(1-oxoisoindolin-2-il)piperidin-1,6-diona sustituidos y usos de estos
|
|
AU2020271123A1
(en)
|
2019-04-10 |
2021-11-25 |
Elevatebio Technologies, Inc. |
FLT3-specific chimeric antigen receptors and methods of using the same
|
|
WO2021052402A1
(zh)
|
2019-09-18 |
2021-03-25 |
四川百利药业有限责任公司 |
一种喜树碱衍生物及其偶联物
|
|
AU2020351751A1
(en)
|
2019-09-25 |
2022-04-21 |
Seagen Inc. |
Combination anti-CD30 ADC, anti-PD-1 and chemotherapeutic for treatment of hematopoietic cancers
|
|
WO2021067820A1
(en)
|
2019-10-04 |
2021-04-08 |
Seagen Inc. |
Formulation of antibody-drug conjugate
|
|
AU2020356955A1
(en)
|
2019-10-04 |
2022-04-14 |
Seagen Inc. |
Camptothecin peptide conjugates
|
|
AU2020379001A1
(en)
|
2019-11-04 |
2022-06-09 |
Paul RUBINSTEIN |
Anti-CD30 antibody-drug conjugates and their use for the treatment of HIV infection
|
|
JP2023507190A
(ja)
|
2019-12-20 |
2023-02-21 |
ノバルティス アーゲー |
増殖性疾患を治療するための抗TGFβ抗体及びチェックポイント阻害薬の使用
|
|
CN114845739B
(zh)
|
2020-01-22 |
2024-07-16 |
上海森辉医药有限公司 |
艾日布林衍生物的药物偶联物、其制备方法及其在医药上的应用
|
|
AU2021212193A1
(en)
|
2020-01-31 |
2022-09-08 |
Celgene Corporation |
Anti-CD30 antibody-drug conjugates and their use for the treatment of non-Hodgkin lymphoma
|
|
BR112022019073A2
(pt)
|
2020-03-25 |
2022-11-08 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
Composição farmacêutica que compreende conjugado anticorpo-fármaco e uso da mesma
|
|
CA3175048A1
(en)
|
2020-03-25 |
2021-09-30 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Preparation method for antibody medicament conjugate
|
|
JP2023520930A
(ja)
|
2020-04-10 |
2023-05-22 |
シージェン インコーポレイテッド |
電荷多様性リンカー
|
|
IL298155A
(en)
|
2020-05-13 |
2023-01-01 |
Seagen Inc |
Methods of treating cancer using a combination of anti-cd30 antibody-drug conjugates
|
|
CA3185455A1
(en)
|
2020-06-11 |
2021-12-16 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
US20230321067A1
(en)
|
2020-06-23 |
2023-10-12 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CA3207893A1
(en)
|
2021-01-15 |
2022-07-21 |
Seagen Inc. |
Immunomodulatory antibody-drug conjugates
|
|
AU2022238571A1
(en)
|
2021-03-18 |
2023-09-14 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
KR20230171980A
(ko)
|
2021-04-20 |
2023-12-21 |
씨젠 인크. |
항체 의존성 세포 독성의 조절
|
|
AR125468A1
(es)
|
2021-04-27 |
2023-07-19 |
Novartis Ag |
Sistema de producción de vectores virales
|
|
CA3221398A1
(en)
|
2021-05-28 |
2022-12-01 |
Seagen Inc. |
Anthracycline antibody conjugates
|
|
KR20240099363A
(ko)
|
2021-10-29 |
2024-06-28 |
씨젠 인크. |
항-pd-1 항체와 항-cd30 항체-약물 접합체의 조합을 사용하여 암을 치료하는 방법
|
|
AU2021362997A1
(en)
|
2021-11-03 |
2024-05-16 |
Hangzhou Dac Biotech Co., Ltd. |
Specific conjugation of an antibody
|
|
CN114891101B
(zh)
*
|
2021-12-02 |
2023-06-16 |
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一种牛肌肉生长抑制素蛋白单克隆抗体及其应用
|
|
PE20242179A1
(es)
|
2022-03-17 |
2024-11-07 |
Seagen Inc |
Conjugados de camptotecina
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
US20250255981A1
(en)
|
2022-05-06 |
2025-08-14 |
Seagen Inc. |
Immunomodulatory antibody-drug conjugates
|
|
IL320293A
(en)
|
2022-10-18 |
2025-06-01 |
Meiji Seika Pharma Co Ltd |
Therapeutic agent for T cell malignancies
|
|
WO2024089639A1
(en)
|
2022-10-26 |
2024-05-02 |
Novartis Ag |
Lentiviral formulations
|
|
EP4634227A1
(en)
|
2022-12-13 |
2025-10-22 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
|
AU2024238898A1
(en)
|
2023-03-22 |
2025-10-16 |
Salubris Biotherapeutics, Inc. |
Anti-5t4 antigen binding domains, antibody-drug conjugates and methods of use thereof
|
|
AU2024276994A1
(en)
|
2023-05-24 |
2025-10-23 |
Kumquat Biosciences Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2025090774A1
(en)
|
2023-10-24 |
2025-05-01 |
Seagen Inc. |
Chemotherapeutic compounds and methods of use
|
|
WO2025096626A1
(en)
|
2023-10-31 |
2025-05-08 |
Seagen Inc. |
Methods of treating cancers using anti-cd30 antibody-drug conjugates
|
|
WO2025149947A1
(en)
|
2024-01-12 |
2025-07-17 |
Seagen Inc. |
Antibody-drug conjugates
|
|
WO2025169056A1
(en)
|
2024-02-06 |
2025-08-14 |
Seagen Inc. |
Methods of treating cancers using anti-cd30 antibody-drug conjugates
|
|
CN119331093B
(zh)
*
|
2024-11-04 |
2025-07-11 |
武汉伊莱瑞特生物科技股份有限公司 |
一种抗CD30的兔源Fab抗体及其制备方法和应用
|