TR200102733T2 - IL-18 kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri - Google Patents

IL-18 kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri

Info

Publication number
TR200102733T2
TR200102733T2 TR2001/02733T TR200102733T TR200102733T2 TR 200102733 T2 TR200102733 T2 TR 200102733T2 TR 2001/02733 T TR2001/02733 T TR 2001/02733T TR 200102733 T TR200102733 T TR 200102733T TR 200102733 T2 TR200102733 T2 TR 200102733T2
Authority
TR
Turkey
Prior art keywords
treatment
recombinant
related disorders
antagonists useful
mabs
Prior art date
Application number
TR2001/02733T
Other languages
English (en)
Inventor
D. Holmes Stephen
Sen Ho Yen
Harrison Taylor Alexander
S. Abdel-Meguid Sherin
Original Assignee
Smithkline Beecham Corporation
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation, Smithkline Beecham P.L.C. filed Critical Smithkline Beecham Corporation
Publication of TR200102733T2 publication Critical patent/TR200102733T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Kimerik, hümanize ve diger IL-18 mAb'ler, yüksek afiniteli nötrleyici mAb'lerden türetilmis olup, bunlari içeren farmasötik terkipler, tedavi ve teshis yöntemleri saglanmaktadir.
TR2001/02733T 1999-03-19 2000-03-17 IL-18 kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri TR200102733T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12529999P 1999-03-19 1999-03-19

Publications (1)

Publication Number Publication Date
TR200102733T2 true TR200102733T2 (tr) 2002-04-22

Family

ID=22419067

Family Applications (3)

Application Number Title Priority Date Filing Date
TR2001/02733T TR200102733T2 (tr) 1999-03-19 2000-03-17 IL-18 kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri
TR2002/02254T TR200202254T2 (tr) 1999-03-19 2000-03-17 IL-18 Kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri.
TR2002/02253T TR200202253T2 (tr) 1999-03-19 2000-03-17 IL-18 Kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri

Family Applications After (2)

Application Number Title Priority Date Filing Date
TR2002/02254T TR200202254T2 (tr) 1999-03-19 2000-03-17 IL-18 Kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri.
TR2002/02253T TR200202253T2 (tr) 1999-03-19 2000-03-17 IL-18 Kaynaklı rahatsızlıkların tedavisinde faydalı rekombinant IL-18 antagonistleri

Country Status (28)

Country Link
US (2) US6706487B1 (tr)
EP (2) EP1163271B1 (tr)
JP (1) JP2002542769A (tr)
KR (1) KR100697120B1 (tr)
CN (1) CN1246335C (tr)
AR (1) AR022952A1 (tr)
AT (1) ATE402191T1 (tr)
AU (1) AU764622B2 (tr)
BR (1) BR0008688A (tr)
CA (1) CA2368965C (tr)
CO (1) CO5470287A1 (tr)
CY (1) CY1108387T1 (tr)
CZ (1) CZ303704B6 (tr)
DE (1) DE60039589D1 (tr)
DK (1) DK1163271T3 (tr)
ES (1) ES2308974T3 (tr)
HK (1) HK1043798B (tr)
HU (1) HU228931B1 (tr)
IL (1) IL144995A0 (tr)
MY (1) MY124219A (tr)
NO (1) NO330391B1 (tr)
NZ (1) NZ513699A (tr)
PL (1) PL202396B1 (tr)
PT (1) PT1163271E (tr)
SI (1) SI1163271T1 (tr)
TR (3) TR200102733T2 (tr)
WO (1) WO2000056771A1 (tr)
ZA (1) ZA200107639B (tr)

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US20100291071A1 (en) * 2008-08-01 2010-11-18 Immunas Pharma, Inc. Antibody Specific Binding to A-Beta Oligomer and the Use
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Also Published As

Publication number Publication date
CN1246335C (zh) 2006-03-22
ES2308974T3 (es) 2008-12-16
NO20014524L (no) 2001-11-14
CO5470287A1 (es) 2004-12-30
DE60039589D1 (de) 2008-09-04
PL350460A1 (en) 2002-12-16
EP1163271A4 (en) 2003-04-09
NO330391B1 (no) 2011-04-04
CY1108387T1 (el) 2014-02-12
AU764622B2 (en) 2003-08-28
AU3901600A (en) 2000-10-09
NO20014524D0 (no) 2001-09-18
EP1163271B1 (en) 2008-07-23
PT1163271E (pt) 2008-09-16
IL144995A0 (en) 2002-06-30
NZ513699A (en) 2004-02-27
WO2000056771A1 (en) 2000-09-28
BR0008688A (pt) 2002-01-08
CN1352650A (zh) 2002-06-05
DK1163271T3 (da) 2008-11-10
PL202396B1 (pl) 2009-06-30
TR200202253T2 (tr) 2002-12-23
CA2368965A1 (en) 2000-09-28
CA2368965C (en) 2010-05-18
ATE402191T1 (de) 2008-08-15
EP1163271A1 (en) 2001-12-19
HK1043798B (zh) 2009-04-09
HUP0200502A2 (en) 2002-06-29
US6706487B1 (en) 2004-03-16
HK1043798A1 (en) 2002-09-27
US20040141964A1 (en) 2004-07-22
KR100697120B1 (ko) 2007-03-20
HU228931B1 (en) 2013-06-28
JP2002542769A (ja) 2002-12-17
AR022952A1 (es) 2002-09-04
HUP0200502A3 (en) 2003-12-29
EP1961768A1 (en) 2008-08-27
TR200202254T2 (tr) 2002-12-23
CZ20013362A3 (cs) 2002-03-13
CZ303704B6 (cs) 2013-03-27
KR20020008130A (ko) 2002-01-29
ZA200107639B (en) 2002-09-17
MY124219A (en) 2006-06-30
SI1163271T1 (sl) 2008-10-31

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