DK1289985T3 - Beta-carbolinderivater anvendelige som phosphodiesteraseinhibitorer - Google Patents

Beta-carbolinderivater anvendelige som phosphodiesteraseinhibitorer

Info

Publication number
DK1289985T3
DK1289985T3 DK01935038T DK01935038T DK1289985T3 DK 1289985 T3 DK1289985 T3 DK 1289985T3 DK 01935038 T DK01935038 T DK 01935038T DK 01935038 T DK01935038 T DK 01935038T DK 1289985 T3 DK1289985 T3 DK 1289985T3
Authority
DK
Denmark
Prior art keywords
beta
phosphodiesterase inhibitors
derivatives useful
carboline derivatives
carboline
Prior art date
Application number
DK01935038T
Other languages
Danish (da)
English (en)
Inventor
Zhihua Sui
Mark J Macielag
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1289985T3 publication Critical patent/DK1289985T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK01935038T 2000-05-17 2001-05-03 Beta-carbolinderivater anvendelige som phosphodiesteraseinhibitorer DK1289985T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20466700P 2000-05-17 2000-05-17
PCT/US2001/014357 WO2001087038A2 (en) 2000-05-17 2001-05-03 β-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE

Publications (1)

Publication Number Publication Date
DK1289985T3 true DK1289985T3 (da) 2004-04-05

Family

ID=22758909

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01935038T DK1289985T3 (da) 2000-05-17 2001-05-03 Beta-carbolinderivater anvendelige som phosphodiesteraseinhibitorer

Country Status (31)

Country Link
US (2) US6492358B2 (cs)
EP (1) EP1289985B1 (cs)
JP (1) JP5014551B2 (cs)
KR (1) KR20030031482A (cs)
CN (1) CN1255403C (cs)
AR (1) AR028576A1 (cs)
AT (1) ATE256127T1 (cs)
AU (2) AU2001261167B2 (cs)
BG (1) BG66141B1 (cs)
CA (1) CA2409715C (cs)
CZ (1) CZ20023934A3 (cs)
DE (1) DE60101479T2 (cs)
DK (1) DK1289985T3 (cs)
ES (1) ES2211806T3 (cs)
GE (1) GEP20053511B (cs)
HR (1) HRP20020910B1 (cs)
HU (1) HUP0302412A3 (cs)
IL (2) IL152873A0 (cs)
MX (1) MXPA02011426A (cs)
MY (1) MY128479A (cs)
NO (1) NO324251B1 (cs)
NZ (1) NZ522731A (cs)
PL (1) PL205507B1 (cs)
PT (1) PT1289985E (cs)
RU (1) RU2271358C2 (cs)
SK (1) SK16972002A3 (cs)
TR (1) TR200302309T4 (cs)
TW (1) TWI286553B (cs)
UA (1) UA74826C2 (cs)
WO (1) WO2001087038A2 (cs)
ZA (1) ZA200210111B (cs)

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AU2008276568A1 (en) * 2007-07-19 2009-01-22 Merck & Co., Inc. Beta carboline derivatives as antidiabetic compounds
JP2011505373A (ja) 2007-11-30 2011-02-24 ビオタ サイエンティフィック マネージメント ピーティーワイ リミテッド 抗菌剤としての２環式ｐｐａｔ阻害剤
CN101945872B (zh) 2008-01-11 2014-07-23 阿尔巴尼分子研究公司 作为mch拮抗剂的(1-吖嗪酮)-取代的吡啶并吲哚
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Also Published As

Publication number Publication date
BG66141B1 (bg) 2011-07-29
US6864253B2 (en) 2005-03-08
UA74826C2 (en) 2006-02-15
CA2409715A1 (en) 2001-11-22
HRP20020910B1 (hr) 2011-02-28
JP5014551B2 (ja) 2012-08-29
HUP0302412A3 (en) 2007-02-28
US20020010189A1 (en) 2002-01-24
EP1289985B1 (en) 2003-12-10
BG107285A (bg) 2003-07-31
ES2211806T3 (es) 2004-07-16
CZ20023934A3 (cs) 2003-10-15
IL152873A0 (en) 2003-06-24
CA2409715C (en) 2010-09-14
DE60101479D1 (en) 2004-01-22
JP2003533453A (ja) 2003-11-11
SK16972002A3 (sk) 2003-11-04
MY128479A (en) 2007-02-28
EP1289985A2 (en) 2003-03-12
NO20025527D0 (no) 2002-11-18
TR200302309T4 (tr) 2004-02-23
CN1446217A (zh) 2003-10-01
WO2001087038A2 (en) 2001-11-22
HUP0302412A2 (hu) 2003-11-28
TWI286553B (en) 2007-09-11
ATE256127T1 (de) 2003-12-15
NO20025527L (no) 2003-01-16
DE60101479T2 (de) 2005-04-28
HK1051368A1 (en) 2003-08-01
PL365445A1 (en) 2005-01-10
PT1289985E (pt) 2004-03-31
AR028576A1 (es) 2003-05-14
WO2001087038A3 (en) 2002-05-16
HRP20020910A2 (en) 2004-12-31
GEP20053511B (en) 2005-05-10
MXPA02011426A (es) 2004-09-06
CN1255403C (zh) 2006-05-10
US20030166641A1 (en) 2003-09-04
NZ522731A (en) 2004-09-24
ZA200210111B (en) 2004-03-12
AU6116701A (en) 2001-11-26
RU2271358C2 (ru) 2006-03-10
PL205507B1 (pl) 2010-04-30
KR20030031482A (ko) 2003-04-21
NO324251B1 (no) 2007-09-17
AU2001261167B2 (en) 2006-10-05
US6492358B2 (en) 2002-12-10
IL152873A (en) 2012-01-31

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