HUP0302412A3 - Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same - Google Patents

Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same

Info

Publication number
HUP0302412A3
HUP0302412A3 HU0302412A HUP0302412A HUP0302412A3 HU P0302412 A3 HUP0302412 A3 HU P0302412A3 HU 0302412 A HU0302412 A HU 0302412A HU P0302412 A HUP0302412 A HU P0302412A HU P0302412 A3 HUP0302412 A3 HU P0302412A3
Authority
HU
Hungary
Prior art keywords
betha
phosphodiesterase
inhibitors
pharmaceutical compositions
same
Prior art date
Application number
HU0302412A
Other languages
English (en)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of HUP0302412A2 publication Critical patent/HUP0302412A2/hu
Publication of HUP0302412A3 publication Critical patent/HUP0302412A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU0302412A 2000-05-17 2001-05-03 Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same HUP0302412A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20466700P 2000-05-17 2000-05-17
PCT/US2001/014357 WO2001087038A2 (en) 2000-05-17 2001-05-03 β-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE

Publications (2)

Publication Number Publication Date
HUP0302412A2 HUP0302412A2 (hu) 2003-11-28
HUP0302412A3 true HUP0302412A3 (en) 2007-02-28

Family

ID=22758909

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302412A HUP0302412A3 (en) 2000-05-17 2001-05-03 Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same

Country Status (32)

Country Link
US (2) US6492358B2 (hu)
EP (1) EP1289985B1 (hu)
JP (1) JP5014551B2 (hu)
KR (1) KR20030031482A (hu)
CN (1) CN1255403C (hu)
AR (1) AR028576A1 (hu)
AT (1) ATE256127T1 (hu)
AU (2) AU6116701A (hu)
BG (1) BG66141B1 (hu)
CA (1) CA2409715C (hu)
CZ (1) CZ20023934A3 (hu)
DE (1) DE60101479T2 (hu)
DK (1) DK1289985T3 (hu)
ES (1) ES2211806T3 (hu)
GE (1) GEP20053511B (hu)
HK (1) HK1051368A1 (hu)
HR (1) HRP20020910B1 (hu)
HU (1) HUP0302412A3 (hu)
IL (2) IL152873A0 (hu)
MX (1) MXPA02011426A (hu)
MY (1) MY128479A (hu)
NO (1) NO324251B1 (hu)
NZ (1) NZ522731A (hu)
PL (1) PL205507B1 (hu)
PT (1) PT1289985E (hu)
RU (1) RU2271358C2 (hu)
SK (1) SK16972002A3 (hu)
TR (1) TR200302309T4 (hu)
TW (1) TWI286553B (hu)
UA (1) UA74826C2 (hu)
WO (1) WO2001087038A2 (hu)
ZA (1) ZA200210111B (hu)

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ATE302775T1 (de) * 2001-02-12 2005-09-15 Lilly Icos Llc Carbolinderivate
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EP1383765B1 (en) * 2001-04-25 2006-12-13 Lilly Icos LLC Carboline derivatives as inhibitors of phosphodiesterase 5 (PDE5) for the treatment of cardiovascular diseases and erectile dysfunction
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DE60213798T2 (de) 2001-06-21 2007-08-16 Lilly Icos Llc, Wilmington Carbolinderivate als pdev inhibitoren
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Also Published As

Publication number Publication date
KR20030031482A (ko) 2003-04-21
US20030166641A1 (en) 2003-09-04
CN1255403C (zh) 2006-05-10
DE60101479T2 (de) 2005-04-28
US6492358B2 (en) 2002-12-10
NO20025527D0 (no) 2002-11-18
SK16972002A3 (sk) 2003-11-04
JP2003533453A (ja) 2003-11-11
AU2001261167B2 (en) 2006-10-05
RU2271358C2 (ru) 2006-03-10
EP1289985B1 (en) 2003-12-10
US20020010189A1 (en) 2002-01-24
PL205507B1 (pl) 2010-04-30
AU6116701A (en) 2001-11-26
BG66141B1 (bg) 2011-07-29
EP1289985A2 (en) 2003-03-12
NZ522731A (en) 2004-09-24
IL152873A (en) 2012-01-31
HRP20020910B1 (en) 2011-02-28
WO2001087038A2 (en) 2001-11-22
WO2001087038A3 (en) 2002-05-16
TR200302309T4 (tr) 2004-02-23
HK1051368A1 (en) 2003-08-01
MY128479A (en) 2007-02-28
DK1289985T3 (da) 2004-04-05
ES2211806T3 (es) 2004-07-16
CA2409715C (en) 2010-09-14
NO20025527L (no) 2003-01-16
MXPA02011426A (es) 2004-09-06
HUP0302412A2 (hu) 2003-11-28
ATE256127T1 (de) 2003-12-15
AR028576A1 (es) 2003-05-14
BG107285A (bg) 2003-07-31
UA74826C2 (en) 2006-02-15
CN1446217A (zh) 2003-10-01
TWI286553B (en) 2007-09-11
GEP20053511B (en) 2005-05-10
CZ20023934A3 (cs) 2003-10-15
CA2409715A1 (en) 2001-11-22
HRP20020910A2 (en) 2004-12-31
NO324251B1 (no) 2007-09-17
PL365445A1 (en) 2005-01-10
ZA200210111B (en) 2004-03-12
DE60101479D1 (en) 2004-01-22
US6864253B2 (en) 2005-03-08
PT1289985E (pt) 2004-03-31
JP5014551B2 (ja) 2012-08-29
IL152873A0 (en) 2003-06-24

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