DK1204755T3 - Proces til biologisk produktion af 1,3-propandiol - Google Patents

Proces til biologisk produktion af 1,3-propandiol

Info

Publication number
DK1204755T3
DK1204755T3 DK00955772T DK00955772T DK1204755T3 DK 1204755 T3 DK1204755 T3 DK 1204755T3 DK 00955772 T DK00955772 T DK 00955772T DK 00955772 T DK00955772 T DK 00955772T DK 1204755 T3 DK1204755 T3 DK 1204755T3
Authority
DK
Denmark
Prior art keywords
propanediol
dehydratase
coli
present
improved process
Prior art date
Application number
DK00955772T
Other languages
Danish (da)
English (en)
Inventor
Mark Emptage
Sharon Haynie
Lisa Laffend
Jeff Pucci
Greg Whited
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Application granted granted Critical
Publication of DK1204755T3 publication Critical patent/DK1204755T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK00955772T 1999-08-18 2000-08-18 Proces til biologisk produktion af 1,3-propandiol DK1204755T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14953499P 1999-08-18 1999-08-18

Publications (1)

Publication Number Publication Date
DK1204755T3 true DK1204755T3 (da) 2006-12-11

Family

ID=22530731

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00955772T DK1204755T3 (da) 1999-08-18 2000-08-18 Proces til biologisk produktion af 1,3-propandiol

Country Status (13)

Country Link
US (5) US6514733B1 (zh)
EP (1) EP1204755B1 (zh)
JP (1) JP4716634B2 (zh)
KR (1) KR100785997B1 (zh)
CN (2) CN101024843A (zh)
AT (1) ATE335823T1 (zh)
BR (2) BR0013315B1 (zh)
CA (2) CA2733616C (zh)
DE (1) DE60029971T2 (zh)
DK (1) DK1204755T3 (zh)
HK (2) HK1044963B (zh)
PT (1) PT1204755E (zh)
WO (1) WO2001012833A2 (zh)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136407A0 (en) * 1997-12-02 2001-06-14 Du Pont Method for the production of glycerol by recombinant organisms
KR20080113283A (ko) 2001-04-04 2008-12-29 제넨코 인터내셔날 인코포레이티드 숙주 세포에서의 생산물의 생산 방법
JP4430869B2 (ja) 2001-04-04 2010-03-10 ジェネンコー・インターナショナル・インク 宿主細胞の分離した生産及び異化経路
JP2002330763A (ja) * 2001-05-02 2002-11-19 Ajinomoto Co Inc 発酵法による目的物質の製造法
US8192959B2 (en) 2002-04-22 2012-06-05 Genencor International Inc Promoter and plasmid system for genetic engineering
US20050079617A1 (en) 2003-10-03 2005-04-14 Cervin Marguerite A. Glucose transport mutants for production of biomaterial
AU2003287028B2 (en) * 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
AU2003277276A1 (en) 2002-10-04 2004-05-04 Genencor International, Inc. Improved production of bacterial strains cross reference to related applications
CN1965088A (zh) 2002-12-16 2007-05-16 纳幕尔杜邦公司 具有改善了的反应动力学的b12－依赖型脱水酶
KR100864672B1 (ko) * 2003-04-02 2008-10-23 씨제이제일제당 (주) 클렙시엘라 뉴모니아를 이용한 1,2-프로판디올의 생산방법
US7056439B2 (en) * 2003-05-06 2006-06-06 Tate & Lyle Ingredidents Americas, Inc. Process for producing 1, 3-propanediol
US7323539B2 (en) 2003-05-06 2008-01-29 E. I. Du Pont De Nemours And Company Polytrimethylene ether glycol and polytrimethylene ether ester with excellent quality
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
US20070148749A1 (en) * 2004-03-26 2007-06-28 Shinzo Yasuda Process for producting 1,3-propanediol and or/3-hydroxypropionic acid
WO2005103262A1 (en) * 2004-04-20 2005-11-03 Cj Corp. A novel diol dehydratase gene cluster in listeria genus
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
WO2006110900A2 (en) * 2005-04-12 2006-10-19 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain ethanol
EP2366727A3 (en) 2005-04-22 2015-05-06 Mitsubishi Chemical Corporation Biomass-resource-derived polyester and production process thereof
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
CN100427605C (zh) * 2005-06-17 2008-10-22 清华大学 一种由粗淀粉原料生产1,3-丙二醇和2,3-丁二醇的方法
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
EP1948814B1 (en) 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
US20080274526A1 (en) * 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
CN100392071C (zh) * 2005-12-05 2008-06-04 中国农业大学 产乳酸途径缺失的工程菌及其构建方法与应用
US20070275139A1 (en) * 2006-02-10 2007-11-29 Melissa Joerger Food compositions comprising renewably-based, biodegradable1,3-propanediol
EP2007210A4 (en) 2006-02-10 2011-07-06 Dupont Tate & Lyle Bio Products Company Llc COMPOSITIONS WITH MONO AND DIESELS FROM 1,3-PROPANEL ON BIOLOGICAL BASIS
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US20080003653A1 (en) * 2006-06-29 2008-01-03 Wenzel J Douglas Supplementation of ethanol fermentations and processes including supplemental components
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
EP2084288A1 (en) * 2006-10-31 2009-08-05 Metabolic Explorer Process for the biological production of 1,3-propanediol from glycerol with high yield
US20080176957A1 (en) * 2006-11-15 2008-07-24 Dupont Tate & Lyle Bio Products Company, Llc Preservative compositions comprising renewably-based, biodegradable 1,3-propanediol
EP3214179B1 (en) 2007-03-16 2021-03-03 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
WO2008130995A2 (en) * 2007-04-18 2008-10-30 E. I. Du Pont De Nemours And Company Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8426174B2 (en) * 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
DE102007027006A1 (de) * 2007-06-08 2008-12-11 Evonik Degussa Gmbh Mikrobiologische Herstellung von Aldehyden, insbesondere von 3-Hydroxypropionaldehyd
CN101130782B (zh) * 2007-07-23 2011-01-26 江南大学 以葡萄糖为底物产1,3-丙二醇重组酿酒酵母的构建方法
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
EP2594645A3 (en) 2007-09-21 2013-11-06 BASF Plant Science GmbH Plants with increased yield
EP3514242A3 (en) 2008-09-10 2019-08-28 Genomatica, Inc. Microrganisms for the production of 1,4-butanediol
BRPI0913547A2 (pt) 2008-09-29 2020-08-18 Butamax Advanced Biofuels Llc célula bacteriana ácido-lática recombinante, método para a produção de 2-butanol e método para a produção de 2-butanona
DE102009029567A1 (de) 2008-10-02 2010-04-08 Basf Se Verfahren zur Abreicherung von Schwefel und/oder schwefelhaltigen Verbindungen aus einer biochemisch hergestellten organischen Verbindung
CN101633928B (zh) * 2008-10-22 2011-09-14 大连理工大学 一种醛还原酶的重组表达及其在甘油生物转化为1,3-丙二醇中的应用
WO2010064744A1 (en) * 2008-12-03 2010-06-10 Korea Research Institute Of Bioscience And Biotechnology Mutant blocked in glycerol oxidaion pathway for producing 1,3-propanediol
US20100159521A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
MX2011007039A (es) 2008-12-31 2011-07-20 Metabolic Explorer Sa Metodo para la preparacion de dioles.
KR101189187B1 (ko) * 2009-03-12 2012-10-10 한국생명공학연구원 글리세롤 산화대사경로를 차단시킨 재조합 균주를 이용한 １、３―프로판디올의 제조방법
US8338148B2 (en) * 2009-03-12 2012-12-25 Korea Research Institute Of Bioscience And Biotechnology Method of producing 1,3-propanediol using recombinant Klebsiella strain in which glycerol oxidative pathway has been blocked
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
EP3199511B1 (en) * 2009-06-04 2020-01-29 Genomatica, Inc. Process of separating components of a fermentation broth
US8969053B2 (en) 2009-07-30 2015-03-03 Metabolic Explorer Mutant YqhD enzyme for the production of a biochemical by fermentation
KR101048485B1 (ko) * 2009-08-17 2011-07-12 부산대학교 산학협력단 재조합 대장균을 배양하여 글리세롤로부터 3-히드록시프로피온산 및 1,3-프로판디올을 동시 생산하는 방법
IN2012DN02878A (zh) 2009-09-09 2015-07-24 Braskem Sa
CN105441374A (zh) * 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
JP5706907B2 (ja) * 2009-10-29 2015-04-22 コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー グリセロールから３−ヒドロキシプロピオン酸を産生する新しい方法
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US20110136190A1 (en) 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
CA2788596A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for producing a monomer component from a genetically modified polyhydroxyalkanoate biomass
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
KR101220499B1 (ko) * 2010-05-25 2013-01-10 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
TWI500768B (zh) * 2010-07-05 2015-09-21 Metabolic Explorer Sa 由蔗糖製備１，３－丙二醇之方法
US8651403B2 (en) 2010-07-21 2014-02-18 E I Du Pont De Nemours And Company Anhydrous ammonia treatment for improved milling of biomass
US20120125551A1 (en) 2010-11-23 2012-05-24 E. I. Du Pont De Nemours And Company Biomass pretreatment process for a packed bed reactor
US20120125548A1 (en) 2010-11-23 2012-05-24 E. I. Du Pont De Nemours And Company Continuously fed biomass pretreatment process for a packed bed reactor
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
CN103347999B (zh) 2010-12-13 2016-02-10 麦兰特公司 使用含有蔗糖的原料生产琥珀酸和其他化学品的方法
EP2689014B1 (en) 2011-03-24 2019-04-24 Butamax (TM) Advanced Biofuels LLC Host cells and methods for production of isobutanol
WO2012142170A2 (en) 2011-04-13 2012-10-18 Elc Management Llc Conditioning agents for personal care compositions
CN103492542B (zh) 2011-04-13 2016-05-25 Elc管理公司 适用于个人护理组合物的温和型阴离子表面活性剂
US20140114082A1 (en) 2011-06-08 2014-04-24 Metabolix, Inc. Biorefinery Process For THF Production
EP2540834A1 (en) * 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
JP2013013353A (ja) * 2011-07-01 2013-01-24 Daicel Corp １，３−プロパンジオールの製造方法
BR112014002859A2 (pt) 2011-08-10 2017-06-13 Metabolix Inc purificação pós-processamento para produção de gama-butiro lactona
JP2013070675A (ja) * 2011-09-28 2013-04-22 Daicel Corp アルキルジオールを産生する組換え菌の培養方法
WO2013126855A1 (en) * 2012-02-23 2013-08-29 The Regents Of The University Of California Atp driven direct photosynthetic production of fuels and chemicals
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
WO2013176909A2 (en) 2012-05-11 2013-11-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
US9605283B2 (en) 2012-07-11 2017-03-28 Institut National Des Sciences Appliquées Microorganism modified for the production of 1,3-propanediol
AU2013323427A1 (en) 2012-09-26 2015-03-05 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
CN104919039A (zh) * 2012-10-18 2015-09-16 阿尔吉诺生物技术有限责任公司 在蓝藻中生产1,3-丙二醇
WO2014062993A1 (en) * 2012-10-18 2014-04-24 Algenol Biofuels Inc. Production of 1,2-propanediol in cyanobacteria
US9845474B2 (en) 2012-10-24 2017-12-19 Calysta, Inc. Engineering of multi-carbon substrate utilization pathways in methanotrophic bacteria
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US20140315258A1 (en) 2013-03-14 2014-10-23 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
US10035749B2 (en) 2013-09-03 2018-07-31 Myriant Corporation Process for manufacturing acrylic acid, acrylonitrile and 1,4-butanediol from 1,3-propanediol
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
KR101577503B1 (ko) 2013-12-16 2015-12-14 지에스칼텍스 주식회사 １，３－프로판디올 생성능이 개선된 재조합 미생물 및 이를 이용한 １，３－프로판디올의 생산 방법
CN103789248B (zh) * 2014-02-14 2016-03-02 江苏大学 一种1,3-丙二醇基因工程菌及转化生产1,3-丙二醇的方法
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
CN104726505A (zh) * 2015-03-31 2015-06-24 上海交通大学 一种利用基因工程蓝藻生产三碳化合物的方法
CN104774879B (zh) * 2015-04-29 2017-10-20 大连理工大学 一种混菌发酵甘油生产1,3‑丙二醇的方法
WO2017017292A1 (es) 2015-07-29 2017-02-02 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expresión de enzimas beta-xilosidasas recombinantes
US9968531B2 (en) 2015-08-05 2018-05-15 Dupont Tate & Lyle Bio Products Company, Llc Deodorants containing 1,3-propanediol
WO2017176875A1 (en) 2016-04-08 2017-10-12 E I Du Pont De Nemours And Company Arabinose isomerases for yeast
CN106906248A (zh) * 2017-03-28 2017-06-30 清华大学 一种利用重组微生物发酵生产1,3‑丙二醇的方法
CN107119003B (zh) * 2017-04-28 2020-04-24 中国科学院青岛生物能源与过程研究所 一种利用葡聚糖合成3-羟基丙酸的重组菌及其构建方法和应用
KR101994772B1 (ko) * 2017-11-09 2019-07-01 지에스칼텍스 주식회사 포도당으로부터 1,3-프로판디올를 생산하는 신규한 크렙시엘라 뉴모니아 균주 및 이를 이용한 1,3 프로판디올의 생산방법
CN108085288B (zh) * 2017-12-22 2021-03-09 广东清大智兴生物技术有限公司 一种利用重组微生物发酵生产1,3-丙二醇的方法
KR102053330B1 (ko) 2018-04-23 2019-12-06 한국과학기술연구원 글리세롤을 포함하는 미생물 발효용 조성물 및 이를 이용한 부티르산의 생산방법
KR102201720B1 (ko) 2018-05-24 2021-01-12 한화솔루션 주식회사 1,3-pdo 생성능을 가지고 3-hp 생성능이 저해된 재조합 코리네박테리움 및 이를 이용한 1,3-pdo의 제조방법
CN109321610B (zh) * 2018-11-01 2022-11-04 上海交通大学 微生物发酵法高效制备2-氨基-1,3-丙二醇
CN110205277A (zh) * 2019-05-14 2019-09-06 河北科技师范学院 肠炎沙门菌glpK基因缺失的应用
CN116064352A (zh) * 2020-03-12 2023-05-05 中国科学院上海高等研究院 高产1,3-丙二醇的克雷伯氏工程菌构建方法及应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用
WO2024117834A1 (ko) * 2022-11-30 2024-06-06 주식회사 엘지화학 1,3-propanediol과 3-hydroxypropionic acid를 동시 생산하는 미생물 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734764A1 (de) 1987-10-14 1989-05-03 Huels Chemische Werke Ag Verfahren zur herstellung von propandiol-(1,3)
DE3878564T2 (de) 1988-12-12 1993-08-19 Unilever Nv Verfahren zur mikrobiologischen herstellung von 1,3-propandiol aus glycerin.
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
ES2336858T3 (es) * 1996-11-13 2010-04-16 E.I. Du Pont De Nemours And Company Metodo para la produccion de 1,3-propanodiol mediante organismos recombinantes.
IL136407A0 (en) 1997-12-02 2001-06-14 Du Pont Method for the production of glycerol by recombinant organisms

Also Published As

Publication number Publication date
CA2380616A1 (en) 2001-02-22
WO2001012833A2 (en) 2001-02-22
BRPI0013315B8 (pt) 2018-02-27
DE60029971D1 (de) 2006-09-21
HK1051055A1 (en) 2003-07-18
US7452710B2 (en) 2008-11-18
US7067300B2 (en) 2006-06-27
CA2733616A1 (en) 2001-02-22
CA2733616C (en) 2016-09-27
EP1204755A2 (en) 2002-05-15
JP4716634B2 (ja) 2011-07-06
US20060121588A1 (en) 2006-06-08
US20060148053A1 (en) 2006-07-06
KR20020059364A (ko) 2002-07-12
CN1379818A (zh) 2002-11-13
HK1044963A1 (en) 2002-11-08
CN1298852C (zh) 2007-02-07
EP1204755B1 (en) 2006-08-09
DE60029971T2 (de) 2007-05-16
CN101024843A (zh) 2007-08-29
JP2003507022A (ja) 2003-02-25
CA2380616C (en) 2011-05-24
US20090253192A1 (en) 2009-10-08
US20030157674A1 (en) 2003-08-21
US7504250B2 (en) 2009-03-17
WO2001012833A3 (en) 2001-08-30
BR0013315B1 (pt) 2013-06-25
KR100785997B1 (ko) 2007-12-14
BR0013315A (pt) 2002-04-02
US6514733B1 (en) 2003-02-04
ATE335823T1 (de) 2006-09-15
PT1204755E (pt) 2006-11-30
HK1044963B (zh) 2007-01-19

Similar Documents

Publication Publication Date Title
DK1204755T3 (da) Proces til biologisk produktion af 1,3-propandiol
Servinsky et al. Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum
DE69831813T2 (de) Herstellungsmethode von glycerin mittels rekombinanten organismen
WO1998021341B1 (en) Method for the recombinant production of 1,3-propanediol
Rajesh et al. Bioengineering advancements, innovations and challenges on green synthesis of 2, 5-furan dicarboxylic acid
IL129722A0 (en) Method for the production of 1,3-propanediol by recombinant organisms
KR970703427A (ko) 식물, 진균류 및 미생물에서 선형 α-1,4 글루칸의 합성을 용이하게 할 수 있는 효소를 코딩하는 DNA 서열(DNA SEQUENCES CODING FOR ENZYMES CAPABLE OF FACILITATING THE SYNTHESIS OF LINEAR α-1,4 GLUCANS IN PLANTS, FUNGI AND MICROORGANISMS)
KR900702042A (ko) 유전공학처리 미생물에 의한 에탄올 생성
CN111094557A (zh) 醇脱氢酶突变体及其在双芳基手性醇合成中的应用
CN111433357A (zh) 醇脱氢酶突变体及其在双芳基手性醇合成中的应用
CN106636020A (zh) 短链脱氢酶的突变体、重组表达载体、基因工程菌和应用
US20130224804A1 (en) Expression of steady state metabolic pathways
DE19523269A1 (de) Verfahren zur Gewinnung von Acyloinen, dafür geeignete Pyruvat-decarboxylase sowie deren Herstellung und DNA-Sequenz des für dieses kodierenden PDC-Gens
Linder A genomic survey of nitrogen assimilation pathways in budding yeasts (sub‐phylum Saccharomycotina)
Shimizu et al. Chiral alcohol synthesis with microbial carbonyl reductases in a water‐organic solvent two‐phase system
CN105593368A (zh) 2,3-丁二醇的生成能力得到增加的重组微生物及利用其的2,3-丁二醇的生产方法
US20210317492A1 (en) A method for production of sugar alcohol from red algae
Bergel et al. First attempts in bioelectrochemical engineering
Eriksen et al. Pathway engineering as an enabling synthetic biology tool
Fiamenghi et al. Comparative Genomics of Firmicutes reveals probable adaptations for xylose fermentation in Thermoanaerobacterium saccharolyticum
Sheldon Sustainability, Green Chemistry and White Biotechnology
KR20070121282A (ko) 1,２―프로판디올 고생성능을 가지는 변이체 및 이를이용한 1,２―프로판디올의 제조방법
Wissinger et al. Duplicated sequence elements and their function in plant mitochondria
KR100531671B1 (ko) 서로 다른 두 개의 유기체의 공동배양을 통한 발효가능한탄소원으로부터 1,3-프로판디올의 생산방법
Tani et al. Thermostable NADP+-Dependent Medium-Chain Alcohol Dehydrogenase from Acinetobacter sp. Strain M-1: Purification an Characterization and Gene Expression in Escherichia coli