DK1194397T3 - Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater - Google Patents

Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater

Info

Publication number
DK1194397T3
DK1194397T3 DK00942111T DK00942111T DK1194397T3 DK 1194397 T3 DK1194397 T3 DK 1194397T3 DK 00942111 T DK00942111 T DK 00942111T DK 00942111 T DK00942111 T DK 00942111T DK 1194397 T3 DK1194397 T3 DK 1194397T3
Authority
DK
Denmark
Prior art keywords
nitroxymethyl
phenyl esters
preparation
acid
derivatives
Prior art date
Application number
DK00942111T
Other languages
Danish (da)
English (en)
Inventor
Graziano Castaldi
Francesca Benedini
Erminio Oldani
Gabriele Razzetti
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of DK1194397T3 publication Critical patent/DK1194397T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK00942111T 1999-07-09 2000-06-21 Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater DK1194397T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico
PCT/EP2000/005722 WO2001004082A1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
EP00942111A EP1194397B1 (de) 1999-07-09 2000-06-21 Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten

Publications (1)

Publication Number Publication Date
DK1194397T3 true DK1194397T3 (da) 2005-01-31

Family

ID=11383309

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00942111T DK1194397T3 (da) 1999-07-09 2000-06-21 Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater

Country Status (25)

Country Link
US (1) US6696591B1 (de)
EP (1) EP1194397B1 (de)
JP (1) JP2003504352A (de)
KR (1) KR100671996B1 (de)
CN (1) CN1165511C (de)
AT (1) ATE276998T1 (de)
AU (1) AU775482B2 (de)
BR (1) BR0012168A (de)
CA (1) CA2377222A1 (de)
DE (1) DE60014088T2 (de)
DK (1) DK1194397T3 (de)
ES (1) ES2228551T3 (de)
HU (1) HUP0201766A3 (de)
IL (1) IL147054A0 (de)
IT (1) ITMI991517A1 (de)
MX (1) MXPA02000245A (de)
NO (1) NO20020052D0 (de)
NZ (1) NZ516125A (de)
PL (1) PL193252B1 (de)
PT (1) PT1194397E (de)
RU (1) RU2235717C2 (de)
SI (1) SI1194397T1 (de)
TR (1) TR200200010T2 (de)
WO (1) WO2001004082A1 (de)
ZA (1) ZA200110276B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
CA2577490A1 (en) 2004-08-26 2006-03-16 Nicholas Piramal India Limited Prodrugs containing alkyldisulfide linker groups
ES2520893T3 (es) 2006-02-03 2014-11-12 Nicox Science Ireland Derivados de nitrooxi para usar en el tratamiento de distrofias musculares
EP2048129A1 (de) * 2007-10-12 2009-04-15 Lonza Ag Verfahren zur Herstellung organischer Nitrate
CN101973879B (zh) * 2010-09-27 2013-03-13 广安凯特医药化工有限公司 一种吉法酯的制备方法
EP3049386B9 (de) 2013-09-24 2020-11-18 Universität zu Köln Verbindungen zur behandlung neoplastischer erkrankungen
US10294188B2 (en) * 2014-02-24 2019-05-21 Natureworks Llc Process for making esters of 2-acetoxyalkanoic acids using an α-hydroxyalkanoic acid ester and an acetate ester as starting materials
ES2837835T3 (es) * 2014-02-24 2021-07-01 Natureworks Llc Procedimiento para preparar un éster 2-acetoxialcanoico
CA2955408A1 (en) * 2014-07-18 2016-01-21 Biocogent, Llc Compositions and methods comprising salicylates and polysalicylates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
JP3646223B2 (ja) * 1992-06-16 2005-05-11 日本農薬株式会社 求電子反応による芳香族化合物の製造方法及び芳香族化合物
AU678063B2 (en) * 1993-10-06 1997-05-15 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
FR2724378B1 (fr) * 1994-09-09 1996-12-20 Rhone Poulenc Chimie Procede de preparation de l'acide picrique
DE19515970A1 (de) * 1995-05-02 1996-11-07 Bayer Ag Acetylsalicylsäurenitrate
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
NZ516125A (en) 2004-06-25
ITMI991517A0 (it) 1999-07-09
TR200200010T2 (tr) 2002-09-23
ITMI991517A1 (it) 2001-01-09
WO2001004082A1 (en) 2001-01-18
HUP0201766A3 (en) 2003-08-28
MXPA02000245A (es) 2004-09-10
US6696591B1 (en) 2004-02-24
EP1194397B1 (de) 2004-09-22
ATE276998T1 (de) 2004-10-15
DE60014088D1 (de) 2004-10-28
JP2003504352A (ja) 2003-02-04
NO20020052L (no) 2002-01-07
NO20020052D0 (no) 2002-01-07
KR100671996B1 (ko) 2007-01-19
CN1360566A (zh) 2002-07-24
CN1165511C (zh) 2004-09-08
AU5684500A (en) 2001-01-30
RU2235717C2 (ru) 2004-09-10
BR0012168A (pt) 2002-03-19
SI1194397T1 (en) 2005-02-28
PT1194397E (pt) 2005-02-28
HUP0201766A2 (en) 2002-10-28
ZA200110276B (en) 2003-05-28
PL352359A1 (en) 2003-08-11
AU775482B2 (en) 2004-08-05
EP1194397A1 (de) 2002-04-10
CA2377222A1 (en) 2001-01-18
ES2228551T3 (es) 2005-04-16
KR20020024298A (ko) 2002-03-29
PL193252B1 (pl) 2007-01-31
DE60014088T2 (de) 2005-10-06
IL147054A0 (en) 2002-08-14

Similar Documents

Publication Publication Date Title
DK1194397T3 (da) Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater
CY1105197T1 (el) Μεθοδος παραγωγης σουλφοναμιδο-υποκατεστημενων ιμιδαζοτριαζινονων
DK1877384T3 (da) Fremgangsmåde til fremstilling af eventuelt 2-substituerede 1,6-dihydro-6-oxo-4-pyrimidincarboxylsyrer
HRP20120031T1 (hr) Postupak kemijskog spajanja sa derivatom fenil boronske kiseline
ATE422200T1 (de) Verfahren zur herstellung substituierter nikotinsäureester
DK1124817T3 (da) Fremgangsmåde til fremstilling af delta-9-tetrahydrocannabinolestere
EP1160236A3 (de) Herstellung von gemischten Säureanhydriden und Amidverbindungen
ATE539071T1 (de) Verfahren zur herstellung von s-(-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-ca bonsäure
ATE417815T1 (de) Verfahren zur herstellung von sorbitan- fettsäureester
EA200100894A1 (ru) Новый способ получения алендроновой кислоты
EP1010701A4 (de) Verfahren zur herstellung von 3-cephemderivaten
JP6289177B2 (ja) 含窒素複素環化合物の製造方法
DK1265837T3 (da) Fremgangsmåde til fremstilling af o-chlormethylbenzoesyrechlorider
ATE288441T1 (de) Beta-ketophosphonaten
TR200200307T2 (tr) Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi
ATE414071T1 (de) Verbessertes verfahren zur herstellung von 4- hydroxypyran-2-onderivaten
AR041057A1 (es) Sintesis y purificacacion de nateglinida
ATE288439T1 (de) Verfahren zur herstellung von formylphenylboronsäuren
ID29954A (id) Stabilitas anhidrida
SU660970A1 (ru) Способ получени 1-адамантилмалоновой кислоты
DK1833790T3 (da) Fremgangsmåde til fremstilling af alkyl 5-(dicarboximid)levulinat og alkyl 4-oxo-pentenoat
HUP0204456A2 (hu) Eljárás (S)-2-acetil-tio-3-fenil-propionsav előállítására
DK1230238T3 (da) Fremgangsmåde til fremstillingen af fumagillin
DK1220867T3 (da) Fremgangsmåde til fremstilling af androst-4-en-17-carboxylsyre
DK1163257T3 (da) Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden