SI1194397T1 - A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives - Google Patents

A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives

Info

Publication number
SI1194397T1
SI1194397T1 SI200030541T SI200030541T SI1194397T1 SI 1194397 T1 SI1194397 T1 SI 1194397T1 SI 200030541 T SI200030541 T SI 200030541T SI 200030541 T SI200030541 T SI 200030541T SI 1194397 T1 SI1194397 T1 SI 1194397T1
Authority
SI
Slovenia
Prior art keywords
salicylic acid
nitroxymethyl
obtaining
acid derivatives
phenyl esters
Prior art date
Application number
SI200030541T
Other languages
English (en)
Slovenian (sl)
Inventor
Graziano Castaldi
Erminio Oldani
Gabriele Razzetti
Francesca Benedini
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of SI1194397T1 publication Critical patent/SI1194397T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200030541T 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives SI1194397T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico
PCT/EP2000/005722 WO2001004082A1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
EP00942111A EP1194397B1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives

Publications (1)

Publication Number Publication Date
SI1194397T1 true SI1194397T1 (en) 2005-02-28

Family

ID=11383309

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030541T SI1194397T1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives

Country Status (25)

Country Link
US (1) US6696591B1 (xx)
EP (1) EP1194397B1 (xx)
JP (1) JP2003504352A (xx)
KR (1) KR100671996B1 (xx)
CN (1) CN1165511C (xx)
AT (1) ATE276998T1 (xx)
AU (1) AU775482B2 (xx)
BR (1) BR0012168A (xx)
CA (1) CA2377222A1 (xx)
DE (1) DE60014088T2 (xx)
DK (1) DK1194397T3 (xx)
ES (1) ES2228551T3 (xx)
HU (1) HUP0201766A3 (xx)
IL (1) IL147054A0 (xx)
IT (1) ITMI991517A1 (xx)
MX (1) MXPA02000245A (xx)
NO (1) NO20020052D0 (xx)
NZ (1) NZ516125A (xx)
PL (1) PL193252B1 (xx)
PT (1) PT1194397E (xx)
RU (1) RU2235717C2 (xx)
SI (1) SI1194397T1 (xx)
TR (1) TR200200010T2 (xx)
WO (1) WO2001004082A1 (xx)
ZA (1) ZA200110276B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
CA2577490A1 (en) 2004-08-26 2006-03-16 Nicholas Piramal India Limited Prodrugs containing alkyldisulfide linker groups
ES2520893T3 (es) 2006-02-03 2014-11-12 Nicox Science Ireland Derivados de nitrooxi para usar en el tratamiento de distrofias musculares
EP2048129A1 (en) * 2007-10-12 2009-04-15 Lonza Ag Method for the preparation of organic nitrates
CN101973879B (zh) * 2010-09-27 2013-03-13 广安凯特医药化工有限公司 一种吉法酯的制备方法
EP3049386B9 (en) 2013-09-24 2020-11-18 Universität zu Köln Compounds useful in the treatment of neoplastic diseases
US10294188B2 (en) * 2014-02-24 2019-05-21 Natureworks Llc Process for making esters of 2-acetoxyalkanoic acids using an α-hydroxyalkanoic acid ester and an acetate ester as starting materials
ES2837835T3 (es) * 2014-02-24 2021-07-01 Natureworks Llc Procedimiento para preparar un éster 2-acetoxialcanoico
CA2955408A1 (en) * 2014-07-18 2016-01-21 Biocogent, Llc Compositions and methods comprising salicylates and polysalicylates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
JP3646223B2 (ja) * 1992-06-16 2005-05-11 日本農薬株式会社 求電子反応による芳香族化合物の製造方法及び芳香族化合物
AU678063B2 (en) * 1993-10-06 1997-05-15 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
FR2724378B1 (fr) * 1994-09-09 1996-12-20 Rhone Poulenc Chimie Procede de preparation de l'acide picrique
DE19515970A1 (de) * 1995-05-02 1996-11-07 Bayer Ag Acetylsalicylsäurenitrate
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
NZ516125A (en) 2004-06-25
ITMI991517A0 (it) 1999-07-09
TR200200010T2 (tr) 2002-09-23
ITMI991517A1 (it) 2001-01-09
WO2001004082A1 (en) 2001-01-18
HUP0201766A3 (en) 2003-08-28
MXPA02000245A (es) 2004-09-10
US6696591B1 (en) 2004-02-24
EP1194397B1 (en) 2004-09-22
ATE276998T1 (de) 2004-10-15
DE60014088D1 (de) 2004-10-28
JP2003504352A (ja) 2003-02-04
NO20020052L (no) 2002-01-07
NO20020052D0 (no) 2002-01-07
KR100671996B1 (ko) 2007-01-19
DK1194397T3 (da) 2005-01-31
CN1360566A (zh) 2002-07-24
CN1165511C (zh) 2004-09-08
AU5684500A (en) 2001-01-30
RU2235717C2 (ru) 2004-09-10
BR0012168A (pt) 2002-03-19
PT1194397E (pt) 2005-02-28
HUP0201766A2 (en) 2002-10-28
ZA200110276B (en) 2003-05-28
PL352359A1 (en) 2003-08-11
AU775482B2 (en) 2004-08-05
EP1194397A1 (en) 2002-04-10
CA2377222A1 (en) 2001-01-18
ES2228551T3 (es) 2005-04-16
KR20020024298A (ko) 2002-03-29
PL193252B1 (pl) 2007-01-31
DE60014088T2 (de) 2005-10-06
IL147054A0 (en) 2002-08-14

Similar Documents

Publication Publication Date Title
IL147054A0 (en) A process for obtaining (nitroxymethy) phenyl esters of salicylic acid derivatives
CA2400919A1 (en) Method for the preparation of fluticasone and related 17beta-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods
MXPA03010183A (es) Proceso para preparar acidos carboxilicos y derivados de los mismos.
NZ598172A (en) Synthesis of boronic ester and acid compounds
TW200610747A (en) Synthesis of unsymmetric anthracene compounds
EP1637523A4 (en) PROCESS FOR PRODUCING A PYRIMIDIN-4-ONE COMPOUND
DE60106204D1 (de) Verfahren zum Herstellen von halogenierten Estern
FI881872A (fi) Menetelmä terapeuttisesti käyttökelpoisten 7-substituoitujen asetamido-3-alkenyyli-3-kefeemijohdannaisten valmistamiseksi
MXPA03005429A (es) Procedimiento para preparacion de imidazotriazinonas sustituidas con sulfonamida.
NO20011999D0 (no) Fremgangsmåte ved fremstilling av <delta>-9- tetrahydrocannabinalestere under anvendelse av et 4-amino-substituert pyridin
DE69803734T2 (de) Verfahren zum Herstellen von Zimtsäureestern
EP1160236A3 (en) Production of mixed acid anhydride and amine compound
DE69937988D1 (de) Verfahren zur herstellung von 3-cephemderivaten
ATE259771T1 (de) Verfahren zur oxidation von xylolderivate
NO20011031D0 (no) FremgangsmÕte for fremstilling av N-beskyttede azetidin-2- karboksylsyrer (AzeOHs)
BR0011490A (pt) Processo para a preparação de ésteres de 1,8-dissubstituìdos-1,3,4,9-tetrahidropirano (3,4-b)-indol-1-ácido acético em um solvente hidroxìlico
GB0123202D0 (en) Beta-ketophosphonates
ATE256100T1 (de) Verfahren zum herstellen von pivaloylessigsäureester
ATE159519T1 (de) Verfahren zur herstellung von n-phenyl-n-(4- piperidinyl)amid-derivaten
HK1078876A1 (en) Method for producing formylphenylboronic acids
BR0013025A (pt) Processo para preparar ácidos via ésteres alfa-cloroepóxi
DE602004017784D1 (de) Verbessertes verfahren zur herstellung von 4-hydroxypyran-2-onderivaten
DE60003871D1 (de) Verfahren zum Herstellen eines tert-Alkylesters einer Carbonsäure
ID29954A (id) Stabilitas anhidrida
CA2389595A1 (en) Improved synthesis of n,n-disubstituted-p-phenylenediamine