ITMI991517A0 - Procedimento per ottenere nitrossimetil fenil esterni di derivati dell 'acido salicilico - Google Patents

Procedimento per ottenere nitrossimetil fenil esterni di derivati dell 'acido salicilico

Info

Publication number
ITMI991517A0
ITMI991517A0 IT99MI001517A ITMI991517A ITMI991517A0 IT MI991517 A0 ITMI991517 A0 IT MI991517A0 IT 99MI001517 A IT99MI001517 A IT 99MI001517A IT MI991517 A ITMI991517 A IT MI991517A IT MI991517 A0 ITMI991517 A0 IT MI991517A0
Authority
IT
Italy
Prior art keywords
nitroximethyl
phenyl
procedure
acid derivatives
salicylic acid
Prior art date
Application number
IT99MI001517A
Other languages
English (en)
Inventor
Graziano Castaldi
Francesca Benedini
Erminio Oldani
Gabriele Razzetti
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Priority to IT1999MI001517A priority Critical patent/ITMI991517A1/it
Publication of ITMI991517A0 publication Critical patent/ITMI991517A0/it
Priority to ES00942111T priority patent/ES2228551T3/es
Priority to MXPA02000245A priority patent/MXPA02000245A/es
Priority to EP00942111A priority patent/EP1194397B1/en
Priority to SI200030541T priority patent/SI1194397T1/xx
Priority to TR2002/00010T priority patent/TR200200010T2/xx
Priority to DK00942111T priority patent/DK1194397T3/da
Priority to PL352359A priority patent/PL193252B1/pl
Priority to HU0201766A priority patent/HUP0201766A3/hu
Priority to CA002377222A priority patent/CA2377222A1/en
Priority to AT00942111T priority patent/ATE276998T1/de
Priority to JP2001509694A priority patent/JP2003504352A/ja
Priority to KR1020027000057A priority patent/KR100671996B1/ko
Priority to PT00942111T priority patent/PT1194397E/pt
Priority to PCT/EP2000/005722 priority patent/WO2001004082A1/en
Priority to RU2002100083/04A priority patent/RU2235717C2/ru
Priority to CNB008100225A priority patent/CN1165511C/zh
Priority to IL14705400A priority patent/IL147054A0/xx
Priority to BR0012168-1A priority patent/BR0012168A/pt
Priority to DE60014088T priority patent/DE60014088T2/de
Priority to NZ516125A priority patent/NZ516125A/en
Priority to US10/019,316 priority patent/US6696591B1/en
Priority to AU56845/00A priority patent/AU775482B2/en
Publication of ITMI991517A1 publication Critical patent/ITMI991517A1/it
Priority to ZA200110276A priority patent/ZA200110276B/xx
Priority to NO20020052A priority patent/NO20020052D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT1999MI001517A 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico ITMI991517A1 (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico
AU56845/00A AU775482B2 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
KR1020027000057A KR100671996B1 (ko) 1999-07-09 2000-06-21 살리실산 유도체들의 (니트록시메틸)페닐에스테르들의수득방법
PCT/EP2000/005722 WO2001004082A1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
EP00942111A EP1194397B1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
SI200030541T SI1194397T1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
TR2002/00010T TR200200010T2 (tr) 1999-07-09 2000-06-21 Salisilik asit türevlerinin (nitroksimetil)fenil esterlerinin elde edilmesi için bir işlem
DK00942111T DK1194397T3 (da) 1999-07-09 2000-06-21 Fremgangsmåde til fremstilling af (nitroxymethyl)phenylestere af salicylderivater
PL352359A PL193252B1 (pl) 1999-07-09 2000-06-21 Sposób wytwarzania estrów (nitroksymetylo)fenylowych pochodnych kwasu salicylowego
HU0201766A HUP0201766A3 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl) phenyl esters of salicylic acid derivatives
CA002377222A CA2377222A1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
AT00942111T ATE276998T1 (de) 1999-07-09 2000-06-21 Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
JP2001509694A JP2003504352A (ja) 1999-07-09 2000-06-21 サリチル酸誘導体の（ニトロキシメチル）フェニルエステルを得るための方法
ES00942111T ES2228551T3 (es) 1999-07-09 2000-06-21 Procedimiento de obtencion de esteres (nitroximetil)fenilo de derivados de acidos salicilicos.
PT00942111T PT1194397E (pt) 1999-07-09 2000-06-21 Processo para a obtencao de esteres de (nitroximetil) fenil de derivados de acido salicilico
MXPA02000245A MXPA02000245A (es) 1999-07-09 2000-06-21 Un procedimiento para obtener esteres (nitroximetil) fenilicos de derivados de acido salicilico.
RU2002100083/04A RU2235717C2 (ru) 1999-07-09 2000-06-21 Способ получения (нитроксиметил)фенил эфиров производных салициловой кислоты
CNB008100225A CN1165511C (zh) 1999-07-09 2000-06-21 制得水杨酸衍生物(硝基氧甲基)苯基酯的方法
IL14705400A IL147054A0 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethy) phenyl esters of salicylic acid derivatives
BR0012168-1A BR0012168A (pt) 1999-07-09 2000-06-21 Processo para a obtenção de compostos
DE60014088T DE60014088T2 (de) 1999-07-09 2000-06-21 Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
NZ516125A NZ516125A (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
US10/019,316 US6696591B1 (en) 1999-07-09 2000-06-21 Process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
ZA200110276A ZA200110276B (en) 1999-07-09 2001-12-13 A process for obtaining (nitroxymethyl) phenyl esters of salicyclic acid derivatives.
NO20020052A NO20020052D0 (no) 1999-07-09 2002-01-07 Fremgangsmåte for fremstilling av nitroksymetylfenylestere av salisylsyrederivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico

Publications (2)

Publication Number Publication Date
ITMI991517A0 true ITMI991517A0 (it) 1999-07-09
ITMI991517A1 ITMI991517A1 (it) 2001-01-09

Family

ID=11383309

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico

Country Status (25)

Country Link
US (1) US6696591B1 (it)
EP (1) EP1194397B1 (it)
JP (1) JP2003504352A (it)
KR (1) KR100671996B1 (it)
CN (1) CN1165511C (it)
AT (1) ATE276998T1 (it)
AU (1) AU775482B2 (it)
BR (1) BR0012168A (it)
CA (1) CA2377222A1 (it)
DE (1) DE60014088T2 (it)
DK (1) DK1194397T3 (it)
ES (1) ES2228551T3 (it)
HU (1) HUP0201766A3 (it)
IL (1) IL147054A0 (it)
IT (1) ITMI991517A1 (it)
MX (1) MXPA02000245A (it)
NO (1) NO20020052D0 (it)
NZ (1) NZ516125A (it)
PL (1) PL193252B1 (it)
PT (1) PT1194397E (it)
RU (1) RU2235717C2 (it)
SI (1) SI1194397T1 (it)
TR (1) TR200200010T2 (it)
WO (1) WO2001004082A1 (it)
ZA (1) ZA200110276B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
CA2432642A1 (en) 2000-12-21 2002-08-08 Subhash P. Khanapure Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
EP1539134A4 (en) 2002-06-11 2007-04-11 Nitromed Inc SELECTIVE INHIBITORS OF CYCLOOXIGENASE-2 NITROSIS AND / OR NITROSYLES, COMPOSITIONS AND METHODS OF USE
US7163958B2 (en) 2002-07-03 2007-01-16 Nitromed Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US7244753B2 (en) 2002-07-29 2007-07-17 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
WO2006027711A2 (en) 2004-08-26 2006-03-16 Nicholas Piramal India Limited Prodrugs and codrugs containing bio- cleavable disulfide linkers
AU2007211508B2 (en) 2006-02-03 2012-08-23 Nicox Science Ireland Use of nitrooxyderivative of drug for the treatment of muscular dystrophies
EP2048129A1 (en) * 2007-10-12 2009-04-15 Lonza Ag Method for the preparation of organic nitrates
CN101973879B (zh) * 2010-09-27 2013-03-13 广安凯特医药化工有限公司 一种吉法酯的制备方法
WO2015044177A1 (en) 2013-09-24 2015-04-02 Universität Zu Köln Compounds useful in the treatment of neoplastic diseases
WO2015127374A1 (en) * 2014-02-24 2015-08-27 Natureworks Llc Process for making esters of 2-acetoxyalkanoic acids using a 3,6-dialkyl-1,4-dioxane-2,5-dione or poly-(alpha-hydroxyalkanoic acid) as a starting material
EP3110788B1 (en) * 2014-02-24 2019-02-06 NatureWorks LLC Process for making esters of 2-acetoxyalkanoic acids using an alpha-hydroxyalkanoic acid ester and an acetate ester as starting materials
CA2955408A1 (en) * 2014-07-18 2016-01-21 Biocogent, Llc Compositions and methods comprising salicylates and polysalicylates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
JP3646223B2 (ja) * 1992-06-16 2005-05-11 日本農薬株式会社 求電子反応による芳香族化合物の製造方法及び芳香族化合物
JP3775796B2 (ja) * 1993-10-06 2006-05-17 ニコックス エス エイ 抗炎症活性及び／又は鎮痛活性を有する硝酸エステル類及びそれらの製造方法
FR2724378B1 (fr) * 1994-09-09 1996-12-20 Rhone Poulenc Chimie Procede de preparation de l'acide picrique
DE19515970A1 (de) * 1995-05-02 1996-11-07 Bayer Ag Acetylsalicylsäurenitrate
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
EP1194397A1 (en) 2002-04-10
KR100671996B1 (ko) 2007-01-19
WO2001004082A1 (en) 2001-01-18
PL352359A1 (en) 2003-08-11
SI1194397T1 (en) 2005-02-28
KR20020024298A (ko) 2002-03-29
HUP0201766A3 (en) 2003-08-28
ES2228551T3 (es) 2005-04-16
AU5684500A (en) 2001-01-30
CA2377222A1 (en) 2001-01-18
BR0012168A (pt) 2002-03-19
RU2235717C2 (ru) 2004-09-10
HUP0201766A2 (en) 2002-10-28
PL193252B1 (pl) 2007-01-31
ATE276998T1 (de) 2004-10-15
DK1194397T3 (da) 2005-01-31
AU775482B2 (en) 2004-08-05
NZ516125A (en) 2004-06-25
IL147054A0 (en) 2002-08-14
NO20020052L (no) 2002-01-07
CN1360566A (zh) 2002-07-24
US6696591B1 (en) 2004-02-24
PT1194397E (pt) 2005-02-28
MXPA02000245A (es) 2004-09-10
EP1194397B1 (en) 2004-09-22
NO20020052D0 (no) 2002-01-07
DE60014088D1 (de) 2004-10-28
ITMI991517A1 (it) 2001-01-09
CN1165511C (zh) 2004-09-08
ZA200110276B (en) 2003-05-28
JP2003504352A (ja) 2003-02-04
TR200200010T2 (tr) 2002-09-23
DE60014088T2 (de) 2005-10-06

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