DE69502982D1 - Herstellung geschützter Aminothiazolylessigsäurederivate - Google Patents

Herstellung geschützter Aminothiazolylessigsäurederivate

Info

Publication number
DE69502982D1
DE69502982D1 DE69502982T DE69502982T DE69502982D1 DE 69502982 D1 DE69502982 D1 DE 69502982D1 DE 69502982 T DE69502982 T DE 69502982T DE 69502982 T DE69502982 T DE 69502982T DE 69502982 D1 DE69502982 D1 DE 69502982D1
Authority
DE
Germany
Prior art keywords
production
acid derivatives
aminothiazolylacetic acid
protected
protected aminothiazolylacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69502982T
Other languages
English (en)
Other versions
DE69502982T2 (de
Inventor
Yoshio Urawa
Ahihiko Shimotani
Takeo Kanai
Masahiko Tsujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Chemical Co Ltd filed Critical Eisai Chemical Co Ltd
Application granted granted Critical
Publication of DE69502982D1 publication Critical patent/DE69502982D1/de
Publication of DE69502982T2 publication Critical patent/DE69502982T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE69502982T 1994-03-30 1995-03-29 Herstellung geschützter Aminothiazolylessigsäurederivate Expired - Fee Related DE69502982T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8261994 1994-03-30
JP13991894 1994-06-22
JP6283543A JPH0867676A (ja) 1994-03-30 1994-11-17 保護アミノチアゾリル酢酸誘導体

Publications (2)

Publication Number Publication Date
DE69502982D1 true DE69502982D1 (de) 1998-07-23
DE69502982T2 DE69502982T2 (de) 1998-12-10

Family

ID=27303972

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69502982T Expired - Fee Related DE69502982T2 (de) 1994-03-30 1995-03-29 Herstellung geschützter Aminothiazolylessigsäurederivate

Country Status (7)

Country Link
US (3) US5665888A (de)
EP (1) EP0675116B1 (de)
JP (1) JPH0867676A (de)
KR (1) KR950032157A (de)
CN (1) CN1056371C (de)
CA (1) CA2145012A1 (de)
DE (1) DE69502982T2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812549B1 (fr) * 2000-08-03 2003-03-21 Aventis Pharma Sa Associations dalfopristine/quinupristine avec le cefpirome
US20100083415A1 (en) * 2008-10-07 2010-04-08 Dawn Beckford Driver arm shade
CN107987091A (zh) * 2017-11-07 2018-05-04 河北九派制药股份有限公司 一种盐酸头孢替安杂质3-甲基头孢替安盐酸盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3145727A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen
DE3374410D1 (en) * 1982-06-28 1987-12-17 Bristol Myers Co Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
JPS6153272A (ja) * 1984-08-24 1986-03-17 Shionogi & Co Ltd グルタル酸誘導体の製法
US4652644A (en) * 1985-04-29 1987-03-24 Bristol-Myers Company Process for preparation of N7 -amidino substituted mitomycin C derivatives
EP0210815A3 (de) * 1985-07-25 1988-04-20 Beecham Group Plc 6-Beta-(alpha-veräthertes oxyimino)-acylamino-Penicillansäure-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
DE69502982T2 (de) 1998-12-10
KR950032157A (ko) 1995-12-20
US5650518A (en) 1997-07-22
CN1114315A (zh) 1996-01-03
EP0675116B1 (de) 1998-06-17
CN1056371C (zh) 2000-09-13
EP0675116A1 (de) 1995-10-04
US5631378A (en) 1997-05-20
CA2145012A1 (en) 1995-10-01
JPH0867676A (ja) 1996-03-12
US5665888A (en) 1997-09-09

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: EISAI CO., LTD., TOKIO/TOKYO, JP

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee