DE69514284T2 - Herstellung von Catechol-Estrogen-Derivaten - Google Patents

Herstellung von Catechol-Estrogen-Derivaten

Info

Publication number
DE69514284T2
DE69514284T2 DE69514284T DE69514284T DE69514284T2 DE 69514284 T2 DE69514284 T2 DE 69514284T2 DE 69514284 T DE69514284 T DE 69514284T DE 69514284 T DE69514284 T DE 69514284T DE 69514284 T2 DE69514284 T2 DE 69514284T2
Authority
DE
Germany
Prior art keywords
catechol
manufacture
estrogen derivatives
estrogen
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69514284T
Other languages
English (en)
Other versions
DE69514284D1 (de
Inventor
Takehiko Suzuki
Sadaaki Komura
Naoko Ishida
Nobuko Ohishi
Kunio Yagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST OF APPLIED BIOCHEMISTRY G
Original Assignee
INST OF APPLIED BIOCHEMISTRY G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3278973A external-priority patent/JP3034093B2/ja
Priority claimed from JP3293802A external-priority patent/JP3034095B2/ja
Priority claimed from JP29380191A external-priority patent/JPH05170790A/ja
Priority claimed from JP3303874A external-priority patent/JP3034098B2/ja
Priority claimed from JP04125472A external-priority patent/JP3128580B2/ja
Priority claimed from JP04125471A external-priority patent/JP3128579B2/ja
Application filed by INST OF APPLIED BIOCHEMISTRY G filed Critical INST OF APPLIED BIOCHEMISTRY G
Application granted granted Critical
Publication of DE69514284D1 publication Critical patent/DE69514284D1/de
Publication of DE69514284T2 publication Critical patent/DE69514284T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0019—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DE69514284T 1991-10-01 1992-09-29 Herstellung von Catechol-Estrogen-Derivaten Expired - Fee Related DE69514284T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP3278973A JP3034093B2 (ja) 1991-10-01 1991-10-01 カテコールエストロゲン配糖体及びその用途
JP3293802A JP3034095B2 (ja) 1991-10-15 1991-10-15 カテコールエストロゲン配糖体及びその用途
JP29380191A JPH05170790A (ja) 1991-10-15 1991-10-15 カテコールエストロゲンの製法
JP3303874A JP3034098B2 (ja) 1991-10-24 1991-10-24 ２−アセチルオキシ−３−オキシ置換−エストロゲンの製法
JP04125472A JP3128580B2 (ja) 1992-04-20 1992-04-20 ２−ベンジルオキシエストロゲン体の製法
JP04125471A JP3128579B2 (ja) 1992-04-20 1992-04-20 ２−ヒドロキシエストロゲン ３−グリコシドの製法

Publications (2)

Publication Number Publication Date
DE69514284D1 DE69514284D1 (de) 2000-02-10
DE69514284T2 true DE69514284T2 (de) 2000-05-31

Family

ID=27552674

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69514284T Expired - Fee Related DE69514284T2 (de) 1991-10-01 1992-09-29 Herstellung von Catechol-Estrogen-Derivaten
DE69220639T Expired - Fee Related DE69220639T2 (de) 1991-10-01 1992-09-29 Herstellung und Verwendung von neuen Glykosiden von Catechol-Östrogenen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69220639T Expired - Fee Related DE69220639T2 (de) 1991-10-01 1992-09-29 Herstellung und Verwendung von neuen Glykosiden von Catechol-Östrogenen

Country Status (4)

Country Link
US (2) US5405944A (de)
EP (2) EP0535595B1 (de)
CA (1) CA2078804C (de)
DE (2) DE69514284T2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen
ATE281170T1 (de) * 1996-05-09 2004-11-15 Amrad Operations Pty Ltd Verwendung von steroiden zur behandlung von asthma und atemwegerkrankungen
AUPO427196A0 (en) * 1996-12-19 1997-01-23 University Of Sydney, The A method for preventing or controlling cataract
US6051726A (en) * 1997-03-13 2000-04-18 Pharm-Eco Laboratories, Inc. Synthesis of 2-alkoxyestradiols
DE19723794A1 (de) * 1997-06-06 1998-12-10 Jenapharm Gmbh Nichtestrogene Derivate des Estradiols mit antioxidativer Aktivität
AUPQ342599A0 (en) * 1999-10-14 1999-11-04 University Of Melbourne, The Conjugates and uses thereof
MXPA04005771A (es) * 2001-12-14 2004-09-10 Matthias Rath Composicion de estrogeno y de otras hormonas con ascorbato, lisina, prolina y otras substancias.
US20070213310A1 (en) * 2002-04-01 2007-09-13 Laszlo Prokai Prodrugs for Use as Ophthalmic Agents
US7186707B2 (en) 2002-04-01 2007-03-06 University Of Florida Prodrugs for use as ophthalmic agents
WO2005110462A2 (en) * 2004-05-04 2005-11-24 Children's Medical Center Corporation Methods and compositions for treatment of preeclampsia
US7717368B2 (en) * 2005-06-07 2010-05-18 Urban Aeronautics Ltd. Apparatus for generating horizontal forces in aerial vehicles and related method
US8592166B2 (en) * 2006-11-21 2013-11-26 Beth Israel Deaconess Medical Center, Inc. Hypoxia related genes and proteins for the treatment and diagnosis of pregnancy related complications
WO2008121171A1 (en) * 2007-01-12 2008-10-09 Cornell Research Foundation, Inc. Adenylyl cyclases as novel targets for antibacterial interventions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216614A3 (de) * 1985-09-19 1988-06-08 The University Of Sheffield Synthese von Steroiden und Zwischenprodukte davon
US4876382A (en) * 1987-01-30 1989-10-24 Central Glass Company, Limited Process for making fluorobenzoic acid fluorophenylesters

Also Published As

Publication number Publication date
US5405944A (en) 1995-04-11
CA2078804C (en) 2003-02-25
EP0535595A2 (de) 1993-04-07
EP0688785A2 (de) 1995-12-27
EP0688785A3 (de) 1997-01-08
EP0535595B1 (de) 1997-07-02
DE69220639T2 (de) 1997-10-16
DE69220639D1 (de) 1997-08-07
EP0535595A3 (en) 1993-05-05
DE69514284D1 (de) 2000-02-10
US5739302A (en) 1998-04-14
CA2078804A1 (en) 1993-04-02
EP0688785B1 (de) 2000-01-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee