ZA200110276B - A process for obtaining (nitroxymethyl) phenyl esters of salicyclic acid derivatives. - Google Patents

A process for obtaining (nitroxymethyl) phenyl esters of salicyclic acid derivatives.

Info

Publication number
ZA200110276B
ZA200110276B ZA200110276A ZA200110276A ZA200110276B ZA 200110276 B ZA200110276 B ZA 200110276B ZA 200110276 A ZA200110276 A ZA 200110276A ZA 200110276 A ZA200110276 A ZA 200110276A ZA 200110276 B ZA200110276 B ZA 200110276B
Authority
ZA
South Africa
Prior art keywords
nitroxymethyl
obtaining
acid derivatives
phenyl esters
salicyclic acid
Prior art date
Application number
ZA200110276A
Other languages
English (en)
Inventor
Graziano Castaldi
Erminio Oldani
Gabriele Razzetti
Francesca Benedini
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of ZA200110276B publication Critical patent/ZA200110276B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200110276A 1999-07-09 2001-12-13 A process for obtaining (nitroxymethyl) phenyl esters of salicyclic acid derivatives. ZA200110276B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico

Publications (1)

Publication Number Publication Date
ZA200110276B true ZA200110276B (en) 2003-05-28

Family

ID=11383309

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200110276A ZA200110276B (en) 1999-07-09 2001-12-13 A process for obtaining (nitroxymethyl) phenyl esters of salicyclic acid derivatives.

Country Status (25)

Country Link
US (1) US6696591B1 (xx)
EP (1) EP1194397B1 (xx)
JP (1) JP2003504352A (xx)
KR (1) KR100671996B1 (xx)
CN (1) CN1165511C (xx)
AT (1) ATE276998T1 (xx)
AU (1) AU775482B2 (xx)
BR (1) BR0012168A (xx)
CA (1) CA2377222A1 (xx)
DE (1) DE60014088T2 (xx)
DK (1) DK1194397T3 (xx)
ES (1) ES2228551T3 (xx)
HU (1) HUP0201766A3 (xx)
IL (1) IL147054A0 (xx)
IT (1) ITMI991517A1 (xx)
MX (1) MXPA02000245A (xx)
NO (1) NO20020052D0 (xx)
NZ (1) NZ516125A (xx)
PL (1) PL193252B1 (xx)
PT (1) PT1194397E (xx)
RU (1) RU2235717C2 (xx)
SI (1) SI1194397T1 (xx)
TR (1) TR200200010T2 (xx)
WO (1) WO2001004082A1 (xx)
ZA (1) ZA200110276B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
CA2577490A1 (en) 2004-08-26 2006-03-16 Nicholas Piramal India Limited Prodrugs containing alkyldisulfide linker groups
ES2520893T3 (es) 2006-02-03 2014-11-12 Nicox Science Ireland Derivados de nitrooxi para usar en el tratamiento de distrofias musculares
EP2048129A1 (en) * 2007-10-12 2009-04-15 Lonza Ag Method for the preparation of organic nitrates
CN101973879B (zh) * 2010-09-27 2013-03-13 广安凯特医药化工有限公司 一种吉法酯的制备方法
EP3049386B9 (en) 2013-09-24 2020-11-18 Universität zu Köln Compounds useful in the treatment of neoplastic diseases
US10294188B2 (en) * 2014-02-24 2019-05-21 Natureworks Llc Process for making esters of 2-acetoxyalkanoic acids using an α-hydroxyalkanoic acid ester and an acetate ester as starting materials
ES2837835T3 (es) * 2014-02-24 2021-07-01 Natureworks Llc Procedimiento para preparar un éster 2-acetoxialcanoico
CA2955408A1 (en) * 2014-07-18 2016-01-21 Biocogent, Llc Compositions and methods comprising salicylates and polysalicylates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
JP3646223B2 (ja) * 1992-06-16 2005-05-11 日本農薬株式会社 求電子反応による芳香族化合物の製造方法及び芳香族化合物
AU678063B2 (en) * 1993-10-06 1997-05-15 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
FR2724378B1 (fr) * 1994-09-09 1996-12-20 Rhone Poulenc Chimie Procede de preparation de l'acide picrique
DE19515970A1 (de) * 1995-05-02 1996-11-07 Bayer Ag Acetylsalicylsäurenitrate
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
NZ516125A (en) 2004-06-25
ITMI991517A0 (it) 1999-07-09
TR200200010T2 (tr) 2002-09-23
ITMI991517A1 (it) 2001-01-09
WO2001004082A1 (en) 2001-01-18
HUP0201766A3 (en) 2003-08-28
MXPA02000245A (es) 2004-09-10
US6696591B1 (en) 2004-02-24
EP1194397B1 (en) 2004-09-22
ATE276998T1 (de) 2004-10-15
DE60014088D1 (de) 2004-10-28
JP2003504352A (ja) 2003-02-04
NO20020052L (no) 2002-01-07
NO20020052D0 (no) 2002-01-07
KR100671996B1 (ko) 2007-01-19
DK1194397T3 (da) 2005-01-31
CN1360566A (zh) 2002-07-24
CN1165511C (zh) 2004-09-08
AU5684500A (en) 2001-01-30
RU2235717C2 (ru) 2004-09-10
BR0012168A (pt) 2002-03-19
SI1194397T1 (en) 2005-02-28
PT1194397E (pt) 2005-02-28
HUP0201766A2 (en) 2002-10-28
PL352359A1 (en) 2003-08-11
AU775482B2 (en) 2004-08-05
EP1194397A1 (en) 2002-04-10
CA2377222A1 (en) 2001-01-18
ES2228551T3 (es) 2005-04-16
KR20020024298A (ko) 2002-03-29
PL193252B1 (pl) 2007-01-31
DE60014088T2 (de) 2005-10-06
IL147054A0 (en) 2002-08-14

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