SI1194397T1 - A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives - Google Patents

A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives

Info

Publication number
SI1194397T1
SI1194397T1 SI200030541T SI200030541T SI1194397T1 SI 1194397 T1 SI1194397 T1 SI 1194397T1 SI 200030541 T SI200030541 T SI 200030541T SI 200030541 T SI200030541 T SI 200030541T SI 1194397 T1 SI1194397 T1 SI 1194397T1
Authority
SI
Slovenia
Prior art keywords
salicylic acid
nitroxymethyl
obtaining
acid derivatives
phenyl esters
Prior art date
Application number
SI200030541T
Other languages
English (en)
Slovenian (sl)
Inventor
Graziano Castaldi
Erminio Oldani
Gabriele Razzetti
Francesca Benedini
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of SI1194397T1 publication Critical patent/SI1194397T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200030541T 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives SI1194397T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI001517A ITMI991517A1 (it) 1999-07-09 1999-07-09 Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico
PCT/EP2000/005722 WO2001004082A1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives
EP00942111A EP1194397B1 (de) 1999-07-09 2000-06-21 Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten

Publications (1)

Publication Number Publication Date
SI1194397T1 true SI1194397T1 (en) 2005-02-28

Family

ID=11383309

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030541T SI1194397T1 (en) 1999-07-09 2000-06-21 A process for obtaining (nitroxymethyl)phenyl esters of salicylic acid derivatives

Country Status (25)

Country Link
US (1) US6696591B1 (de)
EP (1) EP1194397B1 (de)
JP (1) JP2003504352A (de)
KR (1) KR100671996B1 (de)
CN (1) CN1165511C (de)
AT (1) ATE276998T1 (de)
AU (1) AU775482B2 (de)
BR (1) BR0012168A (de)
CA (1) CA2377222A1 (de)
DE (1) DE60014088T2 (de)
DK (1) DK1194397T3 (de)
ES (1) ES2228551T3 (de)
HU (1) HUP0201766A3 (de)
IL (1) IL147054A0 (de)
IT (1) ITMI991517A1 (de)
MX (1) MXPA02000245A (de)
NO (1) NO20020052L (de)
NZ (1) NZ516125A (de)
PL (1) PL193252B1 (de)
PT (1) PT1194397E (de)
RU (1) RU2235717C2 (de)
SI (1) SI1194397T1 (de)
TR (1) TR200200010T2 (de)
WO (1) WO2001004082A1 (de)
ZA (1) ZA200110276B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
JP4092203B2 (ja) 2000-12-21 2008-05-28 ニトロメッド，インク． 新規のシクロオキシゲナーゼ２選択的阻害剤としての置換アリール化合物、組成物、および使用方法
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004004648A2 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
EP1542972A4 (de) 2002-07-29 2008-01-23 Nitromed Inc Cyclooxygenase-2-selektive inhibitoren, zusammensetzung und anwendungsverfahren
AU2005281359A1 (en) 2004-08-26 2006-03-16 Apparao Satyam Prodrugs and codrugs containing novel bio-cleavable disulfide linkers
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
SI1978947T1 (sl) 2006-02-03 2014-12-31 Nicox Science Ireland Riverside One Nitrooksiderivati za uporabo pri zdravljenju mišičnih distrofij
EP2048129A1 (de) * 2007-10-12 2009-04-15 Lonza Ag Verfahren zur Herstellung organischer Nitrate
CN101973879B (zh) * 2010-09-27 2013-03-13 广安凯特医药化工有限公司 一种吉法酯的制备方法
WO2015044177A1 (en) 2013-09-24 2015-04-02 Universität Zu Köln Compounds useful in the treatment of neoplastic diseases
ES2714568T3 (es) * 2014-02-24 2019-05-29 Natureworks Llc Procedimiento para la preparación de ésteres de ácidos 2-acetoxialcanoicos utilizando un éster de ácido alfa-hidroxialcanoico y un éster acetato como sustancias de partida
ES2837835T3 (es) * 2014-02-24 2021-07-01 Natureworks Llc Procedimiento para preparar un éster 2-acetoxialcanoico
EP3201166A4 (de) * 2014-07-18 2018-06-27 Biocogent, LLC Zusammensetzungen und verfahren mit salicylaten und polysalicylaten

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
JP3646223B2 (ja) * 1992-06-16 2005-05-11 日本農薬株式会社 求電子反応による芳香族化合物の製造方法及び芳香族化合物
WO1995009831A1 (en) * 1993-10-06 1995-04-13 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
FR2724378B1 (fr) * 1994-09-09 1996-12-20 Rhone Poulenc Chimie Procede de preparation de l'acide picrique
DE19515970A1 (de) * 1995-05-02 1996-11-07 Bayer Ag Acetylsalicylsäurenitrate
IT1276071B1 (it) 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
AU5684500A (en) 2001-01-30
ATE276998T1 (de) 2004-10-15
PL193252B1 (pl) 2007-01-31
PT1194397E (pt) 2005-02-28
CA2377222A1 (en) 2001-01-18
HUP0201766A3 (en) 2003-08-28
ZA200110276B (en) 2003-05-28
ITMI991517A1 (it) 2001-01-09
IL147054A0 (en) 2002-08-14
DE60014088T2 (de) 2005-10-06
KR100671996B1 (ko) 2007-01-19
CN1360566A (zh) 2002-07-24
EP1194397B1 (de) 2004-09-22
DK1194397T3 (da) 2005-01-31
AU775482B2 (en) 2004-08-05
PL352359A1 (en) 2003-08-11
RU2235717C2 (ru) 2004-09-10
US6696591B1 (en) 2004-02-24
HUP0201766A2 (en) 2002-10-28
CN1165511C (zh) 2004-09-08
ES2228551T3 (es) 2005-04-16
JP2003504352A (ja) 2003-02-04
EP1194397A1 (de) 2002-04-10
WO2001004082A1 (en) 2001-01-18
TR200200010T2 (tr) 2002-09-23
NO20020052D0 (no) 2002-01-07
NO20020052L (no) 2002-01-07
MXPA02000245A (es) 2004-09-10
NZ516125A (en) 2004-06-25
BR0012168A (pt) 2002-03-19
DE60014088D1 (de) 2004-10-28
ITMI991517A0 (it) 1999-07-09
KR20020024298A (ko) 2002-03-29

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