DK1163354T3 - Sammensætninger og fremgangsmåder til hjælpevirusfri produktion af rekombinante adenoassocierede virus - Google Patents

Sammensætninger og fremgangsmåder til hjælpevirusfri produktion af rekombinante adenoassocierede virus

Info

Publication number
DK1163354T3
DK1163354T3 DK00910334T DK00910334T DK1163354T3 DK 1163354 T3 DK1163354 T3 DK 1163354T3 DK 00910334 T DK00910334 T DK 00910334T DK 00910334 T DK00910334 T DK 00910334T DK 1163354 T3 DK1163354 T3 DK 1163354T3
Authority
DK
Denmark
Prior art keywords
virus
aav
raav
recombinant adeno
hybrid
Prior art date
Application number
DK00910334T
Other languages
English (en)
Inventor
Guang-Ping Gao
James M Wilson
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/005870 external-priority patent/WO1999047691A1/en
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of DK1163354T3 publication Critical patent/DK1163354T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R31/00Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
    • G01R31/26Testing of individual semiconductor devices
    • G01R31/27Testing of devices without physical removal from the circuit of which they form part, e.g. compensating for effects surrounding elements
    • G01R31/275Testing of devices without physical removal from the circuit of which they form part, e.g. compensating for effects surrounding elements for testing individual semiconductor components within integrated circuits
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R31/00Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
    • G01R31/28Testing of electronic circuits, e.g. by signal tracer
    • G01R31/316Testing of analog circuits
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R31/00Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
    • G01R31/01Subjecting similar articles in turn to test, e.g. "go/no-go" tests in mass production; Testing objects at points as they pass through a testing station
    • G01R31/013Testing passive components

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  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK00910334T 1999-03-18 2000-02-24 Sammensætninger og fremgangsmåder til hjælpevirusfri produktion af rekombinante adenoassocierede virus DK1163354T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US1999/005870 WO1999047691A1 (en) 1998-03-20 1999-03-18 Compositions and methods for helper-free production of recombinant adeno-associated viruses
US09/404,555 US6258595B1 (en) 1999-03-18 1999-09-23 Compositions and methods for helper-free production of recombinant adeno-associated viruses
PCT/US2000/004755 WO2000055342A1 (en) 1999-03-18 2000-02-24 Compositions and methods for helper-free production of recombinant adeno-associated viruses

Publications (1)

Publication Number Publication Date
DK1163354T3 true DK1163354T3 (da) 2007-05-14

Family

ID=26795484

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00910334T DK1163354T3 (da) 1999-03-18 2000-02-24 Sammensætninger og fremgangsmåder til hjælpevirusfri produktion af rekombinante adenoassocierede virus

Country Status (10)

Country Link
US (1) US6258595B1 (da)
EP (1) EP1163354B1 (da)
AT (1) ATE349542T1 (da)
AU (1) AU767269B2 (da)
CA (1) CA2366861C (da)
DE (1) DE60032586T2 (da)
DK (1) DK1163354T3 (da)
ES (1) ES2277829T3 (da)
PT (1) PT1163354E (da)
WO (1) WO2000055342A1 (da)

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US6258595B1 (en) 2001-07-10
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EP1163354B1 (en) 2006-12-27
DE60032586T2 (de) 2008-01-31
DE60032586D1 (de) 2007-02-08
ATE349542T1 (de) 2007-01-15
ES2277829T3 (es) 2007-08-01
AU767269B2 (en) 2003-11-06
EP1163354A1 (en) 2001-12-19
CA2366861A1 (en) 2000-09-21
CA2366861C (en) 2010-11-16
AU3244600A (en) 2000-10-04

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