MX2018007840A - Materiales y metodos para el tratamiento de la esclerosis lateral amiotrofica y/o la degeneracion lobar frontotemporal. - Google Patents

Materiales y metodos para el tratamiento de la esclerosis lateral amiotrofica y/o la degeneracion lobar frontotemporal.

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Publication number
MX2018007840A
MX2018007840A MX2018007840A MX2018007840A MX2018007840A MX 2018007840 A MX2018007840 A MX 2018007840A MX 2018007840 A MX2018007840 A MX 2018007840A MX 2018007840 A MX2018007840 A MX 2018007840A MX 2018007840 A MX2018007840 A MX 2018007840A
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Mexico
Prior art keywords
methods
lateral sclerosis
amyotrophic lateral
materials
treatment
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MX2018007840A
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English (en)
Inventor
Albert Cowan Chad
sven lundberg Ante
Meda Kabadi Ami
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Crispr Therapeutics Ag
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Publication date
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Publication of MX2018007840A publication Critical patent/MX2018007840A/es

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
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Abstract

La presente solicitud proporciona materiales y métodos para tratar a un paciente con esclerosis lateral amiotrófica (ALS) y/o degeneración lobar frontotemporal (FTLD), ambas ex vivo e in vivo. Además, la presente solicitud proporciona materiales y métodos para la edición para modular la expresión, función o actividad del gen C9ORF72 en una célula mediante edición genómica.
MX2018007840A 2015-12-23 2016-12-22 Materiales y metodos para el tratamiento de la esclerosis lateral amiotrofica y/o la degeneracion lobar frontotemporal. MX2018007840A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562387424P 2015-12-23 2015-12-23
US201662324281P 2016-04-18 2016-04-18
PCT/IB2016/057958 WO2017109757A1 (en) 2015-12-23 2016-12-22 Materials and methods for treatment of amyotrophic lateral sclerosis and/or frontal temporal lobular degeneration

Publications (1)

Publication Number Publication Date
MX2018007840A true MX2018007840A (es) 2019-05-02

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MX2018007840A MX2018007840A (es) 2015-12-23 2016-12-22 Materiales y metodos para el tratamiento de la esclerosis lateral amiotrofica y/o la degeneracion lobar frontotemporal.

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Country Link
US (1) US20210260219A1 (es)
EP (1) EP3394260B1 (es)
JP (1) JP6947729B2 (es)
KR (1) KR20180118111A (es)
CN (1) CN109312339B (es)
AU (1) AU2016376191A1 (es)
BR (1) BR112018012894A2 (es)
CA (1) CA3009308A1 (es)
MX (1) MX2018007840A (es)
SG (1) SG11201805320XA (es)
WO (1) WO2017109757A1 (es)

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