DK1151009T3 - Antimikrobielt/endotoksin-neutraliserende polypeptid - Google Patents

Antimikrobielt/endotoksin-neutraliserende polypeptid

Info

Publication number
DK1151009T3
DK1151009T3 DK00906569T DK00906569T DK1151009T3 DK 1151009 T3 DK1151009 T3 DK 1151009T3 DK 00906569 T DK00906569 T DK 00906569T DK 00906569 T DK00906569 T DK 00906569T DK 1151009 T3 DK1151009 T3 DK 1151009T3
Authority
DK
Denmark
Prior art keywords
antimicrobial
present
patient
polypeptide
endotoxin
Prior art date
Application number
DK00906569T
Other languages
English (en)
Inventor
David M Mann
Original Assignee
Agennix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agennix Inc filed Critical Agennix Inc
Application granted granted Critical
Publication of DK1151009T3 publication Critical patent/DK1151009T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DK00906569T 1999-02-05 2000-01-27 Antimikrobielt/endotoksin-neutraliserende polypeptid DK1151009T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/245,527 US6399570B1 (en) 1999-02-05 1999-02-05 Antimicrobial/endotoxin neutralizing polypeptide
PCT/IB2000/000271 WO2000049040A2 (en) 1999-02-05 2000-01-27 Antimicrobial/endotoxin neutralizing polypeptide

Publications (1)

Publication Number Publication Date
DK1151009T3 true DK1151009T3 (da) 2008-01-28

Family

ID=22927039

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00906569T DK1151009T3 (da) 1999-02-05 2000-01-27 Antimikrobielt/endotoksin-neutraliserende polypeptid

Country Status (12)

Country Link
US (2) US6399570B1 (da)
EP (1) EP1151009B1 (da)
JP (1) JP2002541066A (da)
CN (1) CN1362969A (da)
AT (1) ATE373679T1 (da)
AU (1) AU758150B2 (da)
CA (1) CA2362153C (da)
DE (1) DE60036456T2 (da)
DK (1) DK1151009T3 (da)
ES (1) ES2293892T3 (da)
MX (1) MXPA01007956A (da)
WO (1) WO2000049040A2 (da)

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IL94183A (en) * 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US6399570B1 (en) 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
US7060677B1 (en) 1999-11-11 2006-06-13 Am-Pharma B.V. Antimicrobial activity of the first cationic cluster of human lactoferrin
WO2003094952A1 (en) * 2002-05-10 2003-11-20 Agennix Incorporated Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
AU2003233583A1 (en) * 2002-05-24 2003-12-12 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
WO2004024180A1 (en) 2002-09-16 2004-03-25 Agennix Incorporated Lactoferrin compositions and methods of wound treatment
AU2003298906A1 (en) * 2002-12-06 2004-06-30 Agennix Incorporated Oral lactoferrin in the treatment of sepsis
AU2003296447A1 (en) * 2002-12-10 2004-06-30 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
US7034126B2 (en) 2003-05-14 2006-04-25 Agennix, Inc. Lactoferrin in the treatment of diabetes mellitus
WO2005046571A2 (en) * 2003-06-06 2005-05-26 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
US20050075277A1 (en) * 2003-07-10 2005-04-07 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
US7125963B2 (en) * 2004-03-03 2006-10-24 En N Tech Inc Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions
WO2006047744A2 (en) * 2004-10-26 2006-05-04 Agennix Incorporated Compositions of lactoferrin related peptides and uses thereof
MX2008008548A (es) 2005-12-30 2008-09-10 Evonik Roehm Gmbh Peptidos utiles como petidos penetradores de celulas.
EP2050461A1 (en) 2007-10-19 2009-04-22 PharmaSurgics in Sweden AB Peptides based on the sequence of human lactoferrin and their use
EP2060586A1 (en) 2007-11-14 2009-05-20 PharmaSurgics in Sweden AB New synthetic arginine substituted peptides and their use
US20090209489A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions for the treatment of diabetis, system PH disorders, high blood pressure, and a cancer marker system
US20090209487A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions of carbohydrates as dietary supplements
US20090209486A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions of carbohydrates as dietary supplements
US20090209488A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions for the treatment of exercise induced asthma
US20090208588A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown GERD carbohydrate compositions
CN101294188B (zh) * 2008-06-20 2011-06-15 江南大学 乳铁蛋白抗菌肽及其制备方法与它们的用途
JP5177901B2 (ja) * 2009-12-02 2013-04-10 株式会社明治 栄養組成物
CN101798337B (zh) * 2010-01-29 2013-04-24 中国人民解放军第三军医大学第一附属医院 内毒素中和肽突变体及其应用
EP2481751A1 (en) 2011-01-26 2012-08-01 PharmaSurgics in Sweden AB Human lactoferrin derived peptides
JP5763024B2 (ja) * 2012-09-07 2015-08-12 株式会社明治 栄養組成物
WO2014124047A1 (en) * 2013-02-06 2014-08-14 Academia Sinica Antimicrobial peptides derived from hepatitis b virus core protein arginine-rich domain
WO2016056665A1 (ja) * 2014-10-08 2016-04-14 学校法人慶應義塾 白血球の細胞外トラップ形成の阻害剤
SI3215614T1 (sl) 2014-11-03 2019-11-29 Merck Patent Gmbh Topni fuzijski proteini inteina in postopki za čiščenje biomolekul
JP7161263B6 (ja) * 2016-05-27 2023-03-20 アカデミア シニカ アルギニンリッチドメインに由来する改変抗微生物ペプチド
CN105999236A (zh) * 2016-07-06 2016-10-12 方雅悯 一种治疗牛乳房炎的药剂及其应用

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US6020015A (en) * 1988-09-22 2000-02-01 Gaull; Gerald E. Infant formula compositions and nutrition containing genetically engineered human milk proteins
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US6100054A (en) 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
US5571697A (en) 1989-05-05 1996-11-05 Baylor College Of Medicine Texas Medical Center Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
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WO2003094952A1 (en) 2002-05-10 2003-11-20 Agennix Incorporated Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
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Also Published As

Publication number Publication date
ATE373679T1 (de) 2007-10-15
CA2362153A1 (en) 2000-08-24
CA2362153C (en) 2009-11-24
JP2002541066A (ja) 2002-12-03
EP1151009A2 (en) 2001-11-07
EP1151009B1 (en) 2007-09-19
US7244706B2 (en) 2007-07-17
WO2000049040A3 (en) 2000-12-14
DE60036456T2 (de) 2008-06-19
US6399570B1 (en) 2002-06-04
CN1362969A (zh) 2002-08-07
US20030105006A1 (en) 2003-06-05
AU758150B2 (en) 2003-03-13
MXPA01007956A (es) 2004-08-19
DE60036456D1 (de) 2007-10-31
ES2293892T3 (es) 2008-04-01
AU2822600A (en) 2000-09-04
WO2000049040A2 (en) 2000-08-24

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