ATE373679T1 - Antimikrobiell wirksames oder endotoxin neutralisierendes polypeptid - Google Patents

Antimikrobiell wirksames oder endotoxin neutralisierendes polypeptid

Info

Publication number
ATE373679T1
ATE373679T1 AT00906569T AT00906569T ATE373679T1 AT E373679 T1 ATE373679 T1 AT E373679T1 AT 00906569 T AT00906569 T AT 00906569T AT 00906569 T AT00906569 T AT 00906569T AT E373679 T1 ATE373679 T1 AT E373679T1
Authority
AT
Austria
Prior art keywords
antimicrobial
present
patient
polypeptide
endotoxin
Prior art date
Application number
AT00906569T
Other languages
English (en)
Inventor
David Mann
Original Assignee
Agennix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agennix Inc filed Critical Agennix Inc
Application granted granted Critical
Publication of ATE373679T1 publication Critical patent/ATE373679T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00906569T 1999-02-05 2000-01-27 Antimikrobiell wirksames oder endotoxin neutralisierendes polypeptid ATE373679T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/245,527 US6399570B1 (en) 1999-02-05 1999-02-05 Antimicrobial/endotoxin neutralizing polypeptide

Publications (1)

Publication Number Publication Date
ATE373679T1 true ATE373679T1 (de) 2007-10-15

Family

ID=22927039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00906569T ATE373679T1 (de) 1999-02-05 2000-01-27 Antimikrobiell wirksames oder endotoxin neutralisierendes polypeptid

Country Status (12)

Country Link
US (2) US6399570B1 (de)
EP (1) EP1151009B1 (de)
JP (1) JP2002541066A (de)
CN (1) CN1362969A (de)
AT (1) ATE373679T1 (de)
AU (1) AU758150B2 (de)
CA (1) CA2362153C (de)
DE (1) DE60036456T2 (de)
DK (1) DK1151009T3 (de)
ES (1) ES2293892T3 (de)
MX (1) MXPA01007956A (de)
WO (1) WO2000049040A2 (de)

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US6399570B1 (en) 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
US7060677B1 (en) 1999-11-11 2006-06-13 Am-Pharma B.V. Antimicrobial activity of the first cationic cluster of human lactoferrin
CA2484656A1 (en) * 2002-05-10 2003-12-04 Agennix Incorporated Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
WO2003099207A2 (en) * 2002-05-24 2003-12-04 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
AU2003270690B2 (en) 2002-09-16 2009-07-30 Agennix Incorporated Lactoferrin compositions and methods of wound treatment
CA2508912A1 (en) * 2002-12-06 2004-06-24 Agennix Incorporated Oral lactoferrin in the treatment of sepsis
AU2003296447A1 (en) * 2002-12-10 2004-06-30 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
WO2004103285A2 (en) 2003-05-14 2004-12-02 Agennix Incorporated Lactoferrin in the treatment of diabetes mellitus
EP1635766A4 (de) * 2003-06-06 2009-09-30 Agennix Inc Lactoferrin als adjuvans in krebs-vakzinen
WO2005018542A2 (en) * 2003-07-10 2005-03-03 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
WO2005085287A1 (en) * 2004-03-03 2005-09-15 En-N-Tech, Inc. Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions
WO2006047744A2 (en) * 2004-10-26 2006-05-04 Agennix Incorporated Compositions of lactoferrin related peptides and uses thereof
KR101317100B1 (ko) 2005-12-30 2013-10-15 에보니크 룀 게엠베하 세포-침투성 펩티드로서 유용한 펩티드
EP2050461A1 (de) 2007-10-19 2009-04-22 PharmaSurgics in Sweden AB Peptide basierend auf der menschlichen Lactoferrinsequenz und ihre Verwendung
EP2060586A1 (de) 2007-11-14 2009-05-20 PharmaSurgics in Sweden AB Neue synthetische Arginin-substituierte Peptide und ihre Verwendung
US20090209486A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions of carbohydrates as dietary supplements
US20090209488A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions for the treatment of exercise induced asthma
US20090209487A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions of carbohydrates as dietary supplements
US20090208588A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown GERD carbohydrate compositions
US20090209489A1 (en) * 2008-02-19 2009-08-20 Roger Wayne Brown Compositions for the treatment of diabetis, system PH disorders, high blood pressure, and a cancer marker system
CN101294188B (zh) * 2008-06-20 2011-06-15 江南大学 乳铁蛋白抗菌肽及其制备方法与它们的用途
JP5177901B2 (ja) * 2009-12-02 2013-04-10 株式会社明治 栄養組成物
CN101798337B (zh) * 2010-01-29 2013-04-24 中国人民解放军第三军医大学第一附属医院 内毒素中和肽突变体及其应用
EP2481751A1 (de) * 2011-01-26 2012-08-01 PharmaSurgics in Sweden AB Humanem Lactoferrin abgeleitete Peptide
JP5763024B2 (ja) * 2012-09-07 2015-08-12 株式会社明治 栄養組成物
WO2014124047A1 (en) 2013-02-06 2014-08-14 Academia Sinica Antimicrobial peptides derived from hepatitis b virus core protein arginine-rich domain
CA2972397A1 (en) * 2014-10-08 2016-04-14 Nrl Pharma, Inc. Inhibitor of extracellular trap formation in leukocyte
US10308679B2 (en) * 2014-11-03 2019-06-04 Merck Patent Gmbh Soluble intein fusion proteins and methods for purifying biomolecules
AU2017270201A1 (en) * 2016-05-27 2018-11-29 Academia Sinica Modified antimicrobial peptide derived from an arginine-rich domain
CN105999236A (zh) * 2016-07-06 2016-10-12 方雅悯 一种治疗牛乳房炎的药剂及其应用

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US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
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US5766939A (en) 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
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CA2484656A1 (en) * 2002-05-10 2003-12-04 Agennix Incorporated Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
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Also Published As

Publication number Publication date
CN1362969A (zh) 2002-08-07
MXPA01007956A (es) 2004-08-19
DK1151009T3 (da) 2008-01-28
US20030105006A1 (en) 2003-06-05
AU2822600A (en) 2000-09-04
ES2293892T3 (es) 2008-04-01
CA2362153C (en) 2009-11-24
WO2000049040A3 (en) 2000-12-14
DE60036456T2 (de) 2008-06-19
JP2002541066A (ja) 2002-12-03
US7244706B2 (en) 2007-07-17
US6399570B1 (en) 2002-06-04
EP1151009B1 (de) 2007-09-19
EP1151009A2 (de) 2001-11-07
WO2000049040A2 (en) 2000-08-24
CA2362153A1 (en) 2000-08-24
DE60036456D1 (de) 2007-10-31
AU758150B2 (en) 2003-03-13

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