DK1028737T3 - Humane mesenchymale stamceller fra perifert blod - Google Patents

Humane mesenchymale stamceller fra perifert blod

Info

Publication number
DK1028737T3
DK1028737T3 DK98935544T DK98935544T DK1028737T3 DK 1028737 T3 DK1028737 T3 DK 1028737T3 DK 98935544 T DK98935544 T DK 98935544T DK 98935544 T DK98935544 T DK 98935544T DK 1028737 T3 DK1028737 T3 DK 1028737T3
Authority
DK
Denmark
Prior art keywords
peripheral blood
stem cells
mesenchymal stem
human mesenchymal
individual
Prior art date
Application number
DK98935544T
Other languages
English (en)
Inventor
Mireya Fernandez
Jose J Minguell
Original Assignee
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
Application granted granted Critical
Publication of DK1028737T3 publication Critical patent/DK1028737T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98935544T 1997-07-03 1998-07-01 Humane mesenchymale stamceller fra perifert blod DK1028737T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5165197P 1997-07-03 1997-07-03
PCT/US1998/014001 WO1999001145A1 (en) 1997-07-03 1998-07-01 Human mesenchymal stem cells from peripheral blood

Publications (1)

Publication Number Publication Date
DK1028737T3 true DK1028737T3 (da) 2007-08-13

Family

ID=21972574

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98935544T DK1028737T3 (da) 1997-07-03 1998-07-01 Humane mesenchymale stamceller fra perifert blod

Country Status (11)

Country Link
US (1) US6261549B1 (da)
EP (1) EP1028737B1 (da)
AT (1) ATE358493T1 (da)
AU (1) AU8476698A (da)
CA (1) CA2294944A1 (da)
CY (1) CY1106798T1 (da)
DE (1) DE69837491T2 (da)
DK (1) DK1028737T3 (da)
ES (1) ES2285779T3 (da)
PT (1) PT1028737E (da)
WO (1) WO1999001145A1 (da)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822434D0 (en) * 1998-10-14 1998-12-09 Kennedy Rheumatology Inst Mesenchymal precursor cells
JP2002528398A (ja) * 1998-10-26 2002-09-03 フイラデルフイア・ヘルス・アンド・エデユケーシヨン・コーポレーシヨン ストローマ細胞の使用
US20050153442A1 (en) * 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
CN1352696A (zh) * 1999-03-10 2002-06-05 匹兹堡大学联邦制高等教育 脂肪来源的干细胞和网格
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
AUPQ147799A0 (en) * 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
US8062675B2 (en) * 1999-07-07 2011-11-22 Angioblast Systems, Inc. Mesenchymal precursor cell
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
EP3299452A1 (en) * 2000-12-06 2018-03-28 Anthrogenesis Corporation Method of collecting placental stem cells
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
EP2338983B1 (en) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
CA2438153C (en) * 2001-02-14 2015-06-02 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
FR2820979B1 (fr) * 2001-02-22 2004-03-12 Didier Pourquier Nouvelle application therapeutique du g-csf
US6814961B1 (en) * 2001-05-14 2004-11-09 Gitte S. Jensen Method for enhancing stem cell trafficking
US6723490B2 (en) 2001-11-15 2004-04-20 Kodak Polychrome Graphics Llc Minimization of ablation in thermally imageable elements
US20050095228A1 (en) * 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20050048036A1 (en) * 2001-12-07 2005-03-03 Hedrick Marc H. Methods of using regenerative cells in the treatment of inherited and acquired disorders of the bone, bone marrow, liver, and other tissues
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US8105580B2 (en) * 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US8404229B2 (en) * 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
DK1921133T3 (da) * 2001-12-07 2015-08-24 Cytori Therapeutics Inc System til forarbejdning af lipoaspiratceller
US20050008626A1 (en) * 2001-12-07 2005-01-13 Fraser John K. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20060204556A1 (en) * 2001-12-07 2006-09-14 Cytori Therapeutics, Inc. Cell-loaded prostheses for regenerative intraluminal applications
US7595043B2 (en) * 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US6830862B2 (en) 2002-02-28 2004-12-14 Kodak Polychrome Graphics, Llc Multi-layer imageable element with a crosslinked top layer
AU2003213666A1 (en) * 2002-03-02 2003-09-16 Board Of Regents, The University Of Texas System Local production and/or delivery of anti-cancer agents by stromal cell precursors
WO2003093433A2 (en) * 2002-05-02 2003-11-13 Regents Of The University Of Minnesota Fibrin-based biomatrix
EP1545219A4 (en) * 2002-07-23 2009-09-30 Boston Scient Ltd REGENERATION CELL THERAPY
US20040043009A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of repairing primate mammalian tissue
US20040076620A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of repairing primate mammalian tissue
US20040042997A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of regenerating human tissue
US20040076605A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of regenerating human tissue
US20040136969A1 (en) * 2002-10-02 2004-07-15 New York University Adult bone marrow derived stem cells
US20040101959A1 (en) * 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
WO2004047770A2 (en) 2002-11-26 2004-06-10 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
ATE482725T1 (de) * 2003-04-01 2010-10-15 Us Dept Of Veteran S Affaires Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen.
CN100377165C (zh) * 2003-04-24 2008-03-26 皇家飞利浦电子股份有限公司 无创式左心室的容积测定
EP1658853A4 (en) * 2003-06-27 2009-07-08 Renomedix Inst Inc MEDIUM FOR INTERNAL ADMINISTRATION FOR DISEASES OF NERVES IN THE HEAD WITH MESENCYCLES AS AN ACTIVE SUBSTANCE
US20060210544A1 (en) 2003-06-27 2006-09-21 Renomedix Institute, Inc. Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient
JP4965251B2 (ja) * 2003-07-09 2012-07-04 ウォーソー・オーソペディック・インコーポレーテッド 結合組織成長コンポーネントが豊富に含まれる骨髄画分の単離、及び結合組織の形成を促進するためのその使用
US20050265980A1 (en) * 2004-05-14 2005-12-01 Becton, Dickinson And Company Cell culture environments for the serum-free expansion of mesenchymal stem cells
WO2006004910A2 (en) * 2004-06-28 2006-01-12 Transtarget Inc. Improved bispecific antibodies
US8431397B2 (en) * 2004-09-14 2013-04-30 The Trustees Of Columbia University In The City Of New York Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair
ES2645012T3 (es) 2004-09-24 2017-12-01 Mesoblast, Inc. Método para potenciar la proliferación y/o supervivencia de las células precursoras mesenquimales (MPC)
US20060111778A1 (en) * 2004-10-29 2006-05-25 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
CA2586866A1 (en) * 2004-11-12 2006-05-18 Regents Of The University Of Minnesota A veinous occlusion device and methods of using
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
CA2512667A1 (en) * 2005-01-07 2006-07-07 Takahiro Ochiya Human hepatocyte-like cells and uses thereof
JP5138384B2 (ja) * 2005-01-10 2013-02-06 サイトリ セラピューティクス インコーポレイテッド 医療装置を監視し、管理し、サービスするための装置及び方法
WO2006093857A2 (en) * 2005-02-28 2006-09-08 Regenetech, Inc. Method of providing readily available cellular material derived from peripheral blood and a composition thereof
WO2006121445A2 (en) * 2005-05-10 2006-11-16 United States Of America Department Of Veteran's Affairs Therapy of kidney diseases and multiorgan failure with mesenchymal stem cells and mesenchymal stem cell conditioned media
AU2006202209B2 (en) * 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
EP1888123B1 (en) * 2005-06-08 2013-01-09 Janssen Biotech, Inc. A cellular therapy for ocular degeneration
MX2007016268A (es) * 2005-06-30 2009-02-23 Anthrogenesis Corp Reparacion de membrana timpanica utilizando biotela de colageno derivado de placenta.
EP1919500A2 (en) * 2005-07-13 2008-05-14 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
US7531355B2 (en) 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
MX343814B (es) 2005-10-13 2016-11-24 Anthrogenesis Corp Inmunomodulación usando celulas madre de la placenta.
WO2007059010A2 (en) * 2005-11-14 2007-05-24 Enterprise Partners Venture Capital Stem cell factor therapy for tissue injury
KR20080081088A (ko) 2005-12-29 2008-09-05 안트로제네시스 코포레이션 태반 줄기세포와 제2 세포원으로부터 얻은 줄기세포의 공동배양
DK2471903T3 (da) 2005-12-29 2018-05-28 Anthrogenesis Corp Placentastamcellepopulationer
US8741643B2 (en) * 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
AU2007243221A1 (en) * 2006-04-28 2007-11-08 Tulane University Health Sciences Center Methods for treating diabetes
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
WO2007146106A2 (en) * 2006-06-05 2007-12-21 Cryo- Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
JP2009539378A (ja) * 2006-06-09 2009-11-19 アントフロゲネシス コーポレーション 胎盤環境及び幹細胞を培養するためのその使用
CA2655990A1 (en) * 2006-06-22 2007-12-27 Tai June Yoo Restoration of hearing loss
US20100015104A1 (en) * 2006-07-26 2010-01-21 Cytori Therapeutics, Inc Generation of adipose tissue and adipocytes
EP2617428A1 (en) 2006-08-15 2013-07-24 Agency for Science, Technology and Research Mesenchymal stem cell conditioned medium
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372399B2 (en) * 2006-08-31 2013-02-12 Cardiac Pacemakers, Inc. Bispecific antibodies and agents to enhance stem cell homing
US20080058922A1 (en) * 2006-08-31 2008-03-06 Cardiac Pacemakers, Inc. Methods and devices employing vap-1 inhibitors
US8636995B2 (en) * 2006-08-31 2014-01-28 Cardiac Pacemakers, Inc. Methods and devices to regulate stem cell homing
US20080131522A1 (en) * 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
ZA200902485B (en) * 2006-10-06 2010-07-28 Anthrogenesis Corp Native (telopeptide) placental collagen compositions
US20080124286A1 (en) * 2006-11-28 2008-05-29 Lisson Jerold B Algae supplement and treatment method
US20080124318A1 (en) * 2006-11-28 2008-05-29 Jerold Lisson Algae supplement and treatment method
JP5829377B2 (ja) * 2007-02-06 2015-12-09 ジュン ヨー,タイ 遺伝子治療を使用する神経変性疾患の治療および予防
SI2120977T1 (sl) 2007-02-12 2014-01-31 Anthrogenesis Coroporation Zdravljenje vnetnih bolezni z uporabo placentarnih matičnih celic
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
EP2185693B1 (en) 2007-07-31 2019-07-03 Lifescan, Inc. Differentiation of human embryonic stem cells
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
ES2326772B1 (es) * 2007-09-26 2010-07-26 Fundacion Progreso Y Salud Procedimiento de obtencion de celulas madre mesenquimales con capacidad pluripotente.
NZ617412A (en) 2007-09-28 2015-06-26 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
ATE523585T1 (de) * 2007-11-27 2011-09-15 Lifescan Inc Differenzierung menschlicher embryonaler stammzellen
CA2959401C (en) 2008-02-21 2021-12-07 Centocor Ortho Biotech Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
WO2009116951A2 (en) 2008-03-17 2009-09-24 Agency For Science, Technology And Research Microcarriers for stem cell culture
US8623648B2 (en) 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
CN102159703B (zh) 2008-06-30 2015-11-25 森托科尔奥索生物科技公司 多能干细胞的分化
RU2011103183A (ru) * 2008-06-30 2012-08-10 Сентокор Орто Байотек Инк. (Us) Дифференцирование плюрипотентных стволовых клеток
US20100028307A1 (en) * 2008-07-31 2010-02-04 O'neil John J Pluripotent stem cell differentiation
WO2010021993A1 (en) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
AU2009283216B2 (en) 2008-08-20 2015-04-02 Celularity Inc. Improved cell composition and methods of making the same
EP2331679B1 (en) 2008-09-12 2017-04-19 Cryopraxis Criobiologia LTDA. Ischemic tissue cell therapy
EP2346988B1 (en) 2008-10-31 2017-05-31 Janssen Biotech, Inc. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
US9012218B2 (en) 2008-10-31 2015-04-21 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
BRPI0922184A2 (pt) 2008-11-19 2020-08-18 Anthrogenesis Corporation célula isolada, população isolada de células, matriz ou estrutura sintética permanente ou decelularizada degradável, e , método para tratar um indivíduo
EP3260534A1 (en) 2008-11-20 2017-12-27 Janssen Biotech, Inc. Pluripotent stem cell culture on micro-carriers
BRPI0921996A2 (pt) * 2008-11-20 2015-08-18 Centocor Ortho Biotech Inc Métodos e composições para cultura e ligação de células em substratos planos.
US8790638B2 (en) * 2009-02-04 2014-07-29 Stemedica Cell Technologies, Inc. Compositions of stem cells and stem cell factors and methods for their use and manufacture
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
KR101738324B1 (ko) 2009-05-01 2017-05-19 비미니 테크놀로지스 엘엘씨 조직 및 세포 부유화 이식편의 최적화 시스템, 방법 및 조성물
KR101786735B1 (ko) * 2009-07-20 2017-10-18 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
CA2768644A1 (en) * 2009-07-20 2011-01-27 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
SG177481A1 (en) 2009-07-20 2012-02-28 Janssen Biotech Inc Differentiation of human embryonic stem cells
US20110104805A1 (en) * 2009-10-29 2011-05-05 Centocor Ortho Biotech Inc. Pluripotent Stem Cells
SG181822A1 (en) * 2009-12-23 2012-08-30 Centocor Ortho Biotech Inc Differentiation of human embryonic stem cells
RU2701335C2 (ru) * 2009-12-23 2019-09-25 Янссен Байотек, Инк. Способ получения популяции панкреатических эндокринных клеток, соэкспрессирующих nkx6.1 и инсулин, и способ лечения диабета
BR112012022145A2 (pt) 2010-03-01 2020-10-06 Janssen Biotech, Inc. métodos para purificar células derivadas de células-tronco pluripotentes
KR20220015489A (ko) 2010-04-07 2022-02-08 셀룰래리티 인코포레이티드 태반 줄기 세포를 사용한 혈관신생
CN102933221A (zh) 2010-04-08 2013-02-13 人类起源公司 使用胎盘干细胞治疗结节病
KR101903562B1 (ko) 2010-05-12 2018-10-02 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
WO2013106655A1 (en) 2012-01-11 2013-07-18 The Gid Group, Inc. Method for processing adipose tissue and processing apparatus
US9296984B2 (en) 2010-07-09 2016-03-29 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
BR112013000605B1 (pt) 2010-07-09 2021-11-09 The Gid Group, Inc. Aparelho utilizável para a coleta de material biológico humano e processamento póscoleta do material coletado, conjunto e método para processar material biológico humano
US9206387B2 (en) 2010-07-09 2015-12-08 The Gid Group, Inc. Method and apparatus for processing adipose tissue
BR112013000822B1 (pt) 2010-07-13 2021-02-23 Anthrogenesis Corporation Método in vitro em duas etapas para a produção de uma população decélulas exterminadoras naturais (nk) ativadas
ES2585028T3 (es) 2010-08-31 2016-10-03 Janssen Biotech, Inc. Diferenciación de células madre pluripotentes
EP2853589B1 (en) 2010-08-31 2017-12-27 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
KR101851956B1 (ko) 2010-08-31 2018-04-25 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
ES2384790B1 (es) * 2010-12-10 2013-05-20 Instituto De Salud Carlos Iii Células madre mesenquimales aisladas a partir de sangre periférica.
EP2658557A1 (en) 2010-12-31 2013-11-06 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
US9164079B2 (en) 2011-03-17 2015-10-20 Greyledge Technologies Llc Systems for autologous biological therapeutics
CN104220081A (zh) 2011-06-01 2014-12-17 人类起源公司 利用胎盘干细胞治疗疼痛
MY185016A (en) 2011-07-06 2021-04-30 Cell Therapy Ltd Progenitor cells of mesodermal lineage
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
EP2773746A4 (en) * 2011-11-01 2015-08-05 Neostem Inc COMPOSITIONS OF ADULT MESENCHYMAL STEM CELLS (MSC) AND PREPARATION METHODS THEREOF
KR102203056B1 (ko) 2011-12-22 2021-01-14 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화
US9434920B2 (en) 2012-03-07 2016-09-06 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
CN108103005A (zh) 2012-06-08 2018-06-01 詹森生物科技公司 人胚胎干细胞向胰腺内分泌细胞的分化
BR112015004003B1 (pt) 2012-09-06 2020-05-19 The Gid Group Inc aparelho para processar material biológico humano contendo tecido fibroso e método para processar tecido adiposo
CN105073979B (zh) 2012-12-31 2020-03-06 詹森生物科技公司 使用hb9调节子使人胚胎干细胞分化为胰腺内分泌细胞的方法
JP6529440B2 (ja) 2012-12-31 2019-06-12 ヤンセン バイオテツク,インコーポレーテツド 膵内分泌細胞への分化のためのヒト多能性細胞の懸濁及びクラスタリング
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
CN105008518B (zh) 2012-12-31 2020-08-07 詹森生物科技公司 在空气-液体界面处培养人胚胎干细胞以用于分化成胰腺内分泌细胞
CN115282165A (zh) 2013-02-05 2022-11-04 细胞结构公司 来自胎盘的自然杀伤细胞
WO2015035221A1 (en) 2013-09-05 2015-03-12 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
US20150093367A1 (en) * 2013-09-27 2015-04-02 Global Health Solutions Research Trust Acupoint injection therapy using an enriched cellular mixture
US9617506B2 (en) 2013-11-16 2017-04-11 Terumo Bct, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
BR112016025266A2 (pt) 2014-05-02 2017-08-15 Lifecell Corp instrumentos cirúrgicos, e, método de transplante de tecido adiposo
MX2016015004A (es) 2014-05-16 2017-06-27 Janssen Biotech Inc Uso de moleculas pequeñas para mejorar la expresion de mafa en celulas endocrinas pancreaticas.
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US10286122B2 (en) 2015-10-21 2019-05-14 Lifecell Corporation Systems and methods for tube management
BR112018008059A2 (pt) 2015-10-21 2018-10-23 Lifecell Corp sistemas e métodos para controle de dispositivo médico
CA3008035A1 (en) 2015-12-22 2017-06-29 Lifecell Corporation Syringe filling device for fat transfer
WO2017177002A1 (en) * 2016-04-06 2017-10-12 University Of Florida Research Foundation, Inc. Therapeutic use of electroacupuncture-induced mesenchymal stem cells
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
JP2019526342A (ja) 2016-08-30 2019-09-19 ライフセル コーポレーションLifeCell Corporation 医療用装置を制御するためのシステム及び方法
USD851777S1 (en) 2017-01-30 2019-06-18 Lifecell Corporation Canister-type device for tissue processing
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
JPWO2018207918A1 (ja) * 2017-05-12 2020-03-26 国立大学法人 東京医科歯科大学 移植効率を向上させる間葉系幹細胞の純化方法
US11732233B2 (en) 2017-07-18 2023-08-22 Gid Bio, Inc. Adipose tissue digestion system and tissue processing method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5199942A (en) 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation

Also Published As

Publication number Publication date
ATE358493T1 (de) 2007-04-15
EP1028737A4 (en) 2002-12-04
DE69837491D1 (de) 2007-05-16
CA2294944A1 (en) 1999-01-14
AU8476698A (en) 1999-01-25
EP1028737B1 (en) 2007-04-04
EP1028737A1 (en) 2000-08-23
CY1106798T1 (el) 2012-05-23
WO1999001145A1 (en) 1999-01-14
US6261549B1 (en) 2001-07-17
ES2285779T3 (es) 2007-11-16
DE69837491T2 (de) 2008-01-17
PT1028737E (pt) 2007-07-11

Similar Documents

Publication Publication Date Title
DK1028737T3 (da) Humane mesenchymale stamceller fra perifert blod
NO20001509L (no) Dannelse av hematopoetiske celler fra multipotente neurale stam-celler
WO1999046366A8 (en) Uses for humane non-autologous mesenchymal stem cells
BRPI0418326A (pt) método de regeneração de tecidos
EP0871414A4 (en) TREATED TISSUE FOR IMPLANTATION AND MANUFACTURING METHOD
MXPA02007137A (es) Fuente de tejido hepatico.
NO20035637D0 (no) Karbonmonoksyd forbedrer resultatene av vev og organ transplantater og undertrykker apoptose
DE69941903D1 (de) Behandlung von patienten die eine knochenmarktransplantation oder eine transplantation peripherer blutstammzellen erhalten mit anti-cd20 antikörpern
ATE300310T1 (de) Verfahren zur steigerung von hematopoietischen zellen
DK0946199T3 (da) TGF betal 1-responsive celler fra knoglemarv
WO2004011631A3 (en) Methods and compositions for treating tissue defects using pulsed electromagnetic field stimulus
HK1023599A1 (en) Cells for preventing graft rejection in transplantation and their uses.
IL123642A0 (en) Compositions and methods of use of mononuclear phagocytes to promote axonal regeneration
Werner et al. Muscular and nervous systems of the cubopolyp (Cnidaria)
NO912621L (no) Fremgangsmaate for innfoering av dna i animalske celler.
ATE306278T1 (de) Behandlung von knochenleiden mit adrenomedullin
DE50004024D1 (de) Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation
EP1728857A3 (en) Liver tissue source
NO984175L (no) FremgangsmÕte til Õ drepe mÕlceller i h°stede cellepopulasjoner med en eller flere immunotoksiner
MX9705612A (es) Induccion dirigida por linaje de la diferenciacion de celulas mesenquimatosas humanas de origen.
WO1994006447A3 (en) 60a protein-induced morphogenesis
UA69988A (en) Method for treating complicated choledocholithiasis