DE69837491D1 - Menschliche mesenchymale stammzellen aus peripherem blut - Google Patents

Menschliche mesenchymale stammzellen aus peripherem blut

Info

Publication number
DE69837491D1
DE69837491D1 DE69837491T DE69837491T DE69837491D1 DE 69837491 D1 DE69837491 D1 DE 69837491D1 DE 69837491 T DE69837491 T DE 69837491T DE 69837491 T DE69837491 T DE 69837491T DE 69837491 D1 DE69837491 D1 DE 69837491D1
Authority
DE
Germany
Prior art keywords
mesenchymal stem
peripheral blood
stem cells
human mesenchymal
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837491T
Other languages
English (en)
Other versions
DE69837491T2 (de
Inventor
Mireya Fernandez
Jose J Minguell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osiris Therapeutics Inc
Original Assignee
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
Publication of DE69837491D1 publication Critical patent/DE69837491D1/de
Application granted granted Critical
Publication of DE69837491T2 publication Critical patent/DE69837491T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69837491T 1997-07-03 1998-07-01 Menschliche mesenchymale stammzellen aus peripherem blut Expired - Lifetime DE69837491T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5165197P 1997-07-03 1997-07-03
US51651P 1997-07-03
PCT/US1998/014001 WO1999001145A1 (en) 1997-07-03 1998-07-01 Human mesenchymal stem cells from peripheral blood

Publications (2)

Publication Number Publication Date
DE69837491D1 true DE69837491D1 (de) 2007-05-16
DE69837491T2 DE69837491T2 (de) 2008-01-17

Family

ID=21972574

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837491T Expired - Lifetime DE69837491T2 (de) 1997-07-03 1998-07-01 Menschliche mesenchymale stammzellen aus peripherem blut

Country Status (11)

Country Link
US (1) US6261549B1 (de)
EP (1) EP1028737B1 (de)
AT (1) ATE358493T1 (de)
AU (1) AU8476698A (de)
CA (1) CA2294944A1 (de)
CY (1) CY1106798T1 (de)
DE (1) DE69837491T2 (de)
DK (1) DK1028737T3 (de)
ES (1) ES2285779T3 (de)
PT (1) PT1028737E (de)
WO (1) WO1999001145A1 (de)

Families Citing this family (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822434D0 (en) * 1998-10-14 1998-12-09 Kennedy Rheumatology Inst Mesenchymal precursor cells
WO2000024261A1 (en) * 1998-10-26 2000-05-04 Philadelphia Health & Education Corporation Stromal cell use
CA2366078C (en) * 1999-03-10 2015-09-01 University Of Pittsburgh Of The Commonwealth System Of Higher Education Adipose-derived stem cells and lattices
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
US20030082152A1 (en) * 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
US20050153442A1 (en) * 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
AUPQ147799A0 (en) * 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
US8062675B2 (en) * 1999-07-07 2011-11-22 Angioblast Systems, Inc. Mesenchymal precursor cell
ES2522890T3 (es) 2000-12-06 2014-11-19 Anthrogenesis Corporation Método para recolectar células troncales placentarias
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
ES2522526T3 (es) * 2001-02-14 2014-11-14 Anthrogenesis Corporation Placenta post-parto de mamíferos, su uso y células troncales placentarias de la misma
EP2336299A1 (de) 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen
FR2820979B1 (fr) * 2001-02-22 2004-03-12 Didier Pourquier Nouvelle application therapeutique du g-csf
US6814961B1 (en) * 2001-05-14 2004-11-09 Gitte S. Jensen Method for enhancing stem cell trafficking
US6723490B2 (en) 2001-11-15 2004-04-20 Kodak Polychrome Graphics Llc Minimization of ablation in thermally imageable elements
US7595043B2 (en) * 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
KR100930139B1 (ko) 2001-12-07 2009-12-07 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
US20050095228A1 (en) * 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US8404229B2 (en) * 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
US20050008626A1 (en) * 2001-12-07 2005-01-13 Fraser John K. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US7514075B2 (en) * 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US20060204556A1 (en) * 2001-12-07 2006-09-14 Cytori Therapeutics, Inc. Cell-loaded prostheses for regenerative intraluminal applications
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20050048036A1 (en) * 2001-12-07 2005-03-03 Hedrick Marc H. Methods of using regenerative cells in the treatment of inherited and acquired disorders of the bone, bone marrow, liver, and other tissues
US6830862B2 (en) 2002-02-28 2004-12-14 Kodak Polychrome Graphics, Llc Multi-layer imageable element with a crosslinked top layer
CA2477411A1 (en) * 2002-03-02 2003-09-12 Board Of Regents, The University Of Texas Local production and/or delivery of anti-cancer agents by stromal cell precursors
AU2003228808A1 (en) * 2002-05-02 2003-11-17 Regents Of The University Of Minnesota Fibrin-based biomatrix
US20040018174A1 (en) * 2002-07-23 2004-01-29 Boston Scientific Corporation Cell therapy for regeneration
US20040042997A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of regenerating human tissue
US20040076620A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of repairing primate mammalian tissue
US20040043009A1 (en) * 2002-09-03 2004-03-04 Donnie Rudd Method of repairing primate mammalian tissue
US20040076605A1 (en) * 2002-09-03 2004-04-22 Donnie Rudd Method of regenerating human tissue
US20040136969A1 (en) * 2002-10-02 2004-07-15 New York University Adult bone marrow derived stem cells
US20040101959A1 (en) * 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
US20040171147A1 (en) 2002-11-26 2004-09-02 Hariri Robert J. Cytotherapeutics, cytotherapeutic units and methods for treatments using them
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
DE602004029337D1 (de) * 2003-04-01 2010-11-11 Us Dept Of Veteran S Affaires Auf stammzellen, vorläuferzellen oder targetzellen basierende behandlung von multiorganversagen.
WO2004097720A1 (en) * 2003-04-24 2004-11-11 Koninklijke Philips Electronics N.V. Non-invasive left ventricular volume determination
EP1658853A4 (de) * 2003-06-27 2009-07-08 Renomedix Inst Inc Mittel zur inneren verabreichung gegen erkrankungen von nerven im kopf mit mesenchymzellen als wirkstoff
US20060210544A1 (en) 2003-06-27 2006-09-21 Renomedix Institute, Inc. Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient
KR101099315B1 (ko) * 2003-07-09 2011-12-26 워쏘우 오르쏘페딕 인코포레이티드 결합조직 성장 성분이 풍부한 골수 분절의 분리 및 결합조직의 형성을 촉진하기 위한 그 용도
JP2007536936A (ja) * 2004-05-14 2007-12-20 ベクトン・ディキンソン・アンド・カンパニー 幹細胞集団および使用方法
WO2006004910A2 (en) * 2004-06-28 2006-01-12 Transtarget Inc. Improved bispecific antibodies
US8431397B2 (en) * 2004-09-14 2013-04-30 The Trustees Of Columbia University In The City Of New York Differentiation of human mesenchymal stem cells to cardiac progenitor cells that promote cardiac repair
EP2361970A1 (de) 2004-09-24 2011-08-31 Angioblast Systems Incorporated Verfahren zur Verbesserung der Vermehrung und/oder des Überlebens von Mesenchymalvorläuferzellen (MPC)
WO2006050213A2 (en) * 2004-10-29 2006-05-11 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
US20090131866A1 (en) * 2004-11-12 2009-05-21 Regents Of The University Of Minnesota Veinous Occlusion Device and Methods of Using
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
CA2512667A1 (en) * 2005-01-07 2006-07-07 Takahiro Ochiya Human hepatocyte-like cells and uses thereof
EP1844434A4 (de) * 2005-01-10 2013-11-13 Cytori Therapeutics Inc Einrichtungen und verfahren zum überwachen, verwalten und warten medizinischer einrichtungen
CA2599274A1 (en) * 2005-02-28 2006-09-08 Regenetech, Inc. Method of providing readily available cellular material derived from peripheral blood and a composition thereof
BRPI0520280A2 (pt) * 2005-05-10 2009-04-28 Us Of America Dept Of Veteran terapia de disfunÇÕes renais e falÊncia méltipla de àrgços com cÉlulas-tronco mesenquimais e meio condicionado por exposiÇço a cÉlulas-tronco mesenquimais
AU2006202209B2 (en) * 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
US9074189B2 (en) * 2005-06-08 2015-07-07 Janssen Biotech, Inc. Cellular therapy for ocular degeneration
JP2008544818A (ja) * 2005-06-30 2008-12-11 アントフロゲネシス コーポレーション 胎盤由来コラーゲンバイオ線維を用いた鼓膜の修復
EP1919500A2 (de) * 2005-07-13 2008-05-14 Anthrogenesis Corporation Behandlung von beingeschwüren mit kollagen-biogewebe aus plazenta
US7531355B2 (en) 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
WO2007047468A2 (en) * 2005-10-13 2007-04-26 Anthrogenesis Corporation Immunomodulation using placental stem cells
AU2006315601A1 (en) * 2005-11-14 2007-05-24 Enterprise Partners Venture Capital Stem cell factor therapy for tissue injury
KR20190104428A (ko) 2005-12-29 2019-09-09 안트로제네시스 코포레이션 태반 줄기 세포 집단
US8455250B2 (en) 2005-12-29 2013-06-04 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
AU2007243221A1 (en) * 2006-04-28 2007-11-08 Tulane University Health Sciences Center Methods for treating diabetes
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
WO2007146106A2 (en) * 2006-06-05 2007-12-21 Cryo- Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
EP2035552A2 (de) * 2006-06-09 2009-03-18 Anthrogenesis Corporation Plazentare nische und ihre verwendung zur züchtung von stammzellen
CA2655990A1 (en) * 2006-06-22 2007-12-27 Tai June Yoo Restoration of hearing loss
US20100015104A1 (en) * 2006-07-26 2010-01-21 Cytori Therapeutics, Inc Generation of adipose tissue and adipocytes
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
EP2617428A1 (de) 2006-08-15 2013-07-24 Agency for Science, Technology and Research Mit mesenchymalen Stammzellen konditioniertes Medium
US8372399B2 (en) * 2006-08-31 2013-02-12 Cardiac Pacemakers, Inc. Bispecific antibodies and agents to enhance stem cell homing
US20080058922A1 (en) * 2006-08-31 2008-03-06 Cardiac Pacemakers, Inc. Methods and devices employing vap-1 inhibitors
US8636995B2 (en) * 2006-08-31 2014-01-28 Cardiac Pacemakers, Inc. Methods and devices to regulate stem cell homing
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
JP5769925B2 (ja) 2006-10-06 2015-08-26 アントフロゲネシス コーポレーション ヒト胎盤コラーゲン組成物、並びにそれらの製造方法及び使用方法
US20080124286A1 (en) * 2006-11-28 2008-05-29 Lisson Jerold B Algae supplement and treatment method
US20080124318A1 (en) * 2006-11-28 2008-05-29 Jerold Lisson Algae supplement and treatment method
RU2471487C2 (ru) * 2007-02-06 2013-01-10 Тай Джун ЙОО Лечение и предупреждение нейродегенеративных заболеваний с использованием генной терапии
MX349225B (es) 2007-02-12 2017-07-19 Anthrogenesis Corp Uso de celulas madre placentarias para preparar medicamentos utiles en el tratamiento de padecimientos inflamatorios.
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
KR101617243B1 (ko) 2007-07-31 2016-05-02 라이프스캔, 인코포레이티드 인간 배아 줄기 세포의 분화
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
ES2326772B1 (es) * 2007-09-26 2010-07-26 Fundacion Progreso Y Salud Procedimiento de obtencion de celulas madre mesenquimales con capacidad pluripotente.
KR20210022148A (ko) 2007-09-28 2021-03-02 안트로제네시스 코포레이션 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법
EP2229434B1 (de) 2007-11-27 2011-09-07 Lifescan, Inc. Differenzierung menschlicher embryonaler stammzellen
CN102046779A (zh) 2008-02-21 2011-05-04 森托科尔奥索生物科技公司 用于细胞粘附、培养和分离的方法、表面改性培养板和组合物
SG188918A1 (de) 2008-03-17 2013-04-30 Agency Science Tech & Res
US8623648B2 (en) 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
RU2011103183A (ru) * 2008-06-30 2012-08-10 Сентокор Орто Байотек Инк. (Us) Дифференцирование плюрипотентных стволовых клеток
PL2310492T3 (pl) 2008-06-30 2015-12-31 Janssen Biotech Inc Różnocowanie pluripotencjalnych komórek macierzystych
US20100028307A1 (en) * 2008-07-31 2010-02-04 O'neil John J Pluripotent stem cell differentiation
WO2010021993A1 (en) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
EP3539380A3 (de) 2008-08-20 2019-12-18 Celularity, Inc. Verbesserte zellzusammensetzung und verfahren zur herstellung davon
WO2010031006A1 (en) 2008-09-12 2010-03-18 Cryopraxis Criobiologia Ltda. Ischemic tissue cell therapy
KR102025158B1 (ko) 2008-10-31 2019-09-25 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 췌장 내분비 계통으로의 분화
AU2009308967C1 (en) 2008-10-31 2017-04-20 Janssen Biotech, Inc. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
DK2367932T3 (da) 2008-11-19 2019-09-23 Celularity Inc Amnion-afledte adhærente celler
AU2009316583B2 (en) * 2008-11-20 2016-04-21 Janssen Biotech, Inc. Methods and compositions for cell attachment and cultivation on planar substrates
MX356756B (es) 2008-11-20 2018-06-11 Centocor Ortho Biotech Inc Células madre pluripotentes en microportadores.
US8790638B2 (en) * 2009-02-04 2014-07-29 Stemedica Cell Technologies, Inc. Compositions of stem cells and stem cell factors and methods for their use and manufacture
AU2010242780B2 (en) 2009-05-01 2016-04-21 Puregraft Llc Systems, methods and compositions for optimizing tissue and cell enriched grafts
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
EP2456862A4 (de) 2009-07-20 2013-02-27 Janssen Biotech Inc Differenzierung menschlicher embryonischer stammzellen
AU2010276440B2 (en) * 2009-07-20 2014-07-03 Janssen Biotech Inc. Differentiation of human embryonic stem cells
SG177416A1 (en) * 2009-07-20 2012-02-28 Janssen Biotech Inc Differentiation of human embryonic stem cells
CN107058389A (zh) * 2009-10-29 2017-08-18 詹森生物科技公司 多能干细胞
CN102712902B (zh) * 2009-12-23 2019-01-08 詹森生物科技公司 人胚胎干细胞的分化
CN102741395B (zh) * 2009-12-23 2016-03-16 詹森生物科技公司 人胚胎干细胞的分化
RU2702198C2 (ru) 2010-03-01 2019-10-04 Янссен Байотек, Инк. Способы очистки клеток, производных от плюрипотентных стволовых клеток
HUE029144T2 (hu) 2010-04-07 2017-02-28 Anthrogenesis Corp Angiogenezis méhlepény õssejtek használatával
CA2795401A1 (en) 2010-04-08 2011-10-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
RU2587634C2 (ru) 2010-05-12 2016-06-20 Янссен Байотек, Инк. Дифференцирование эмбриональных стволовых клеток человека
US9296984B2 (en) 2010-07-09 2016-03-29 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
US9260697B2 (en) 2010-07-09 2016-02-16 The Gid Group, Inc. Apparatus and methods relating to collecting and processing human biological material containing adipose
WO2013106655A1 (en) 2012-01-11 2013-07-18 The Gid Group, Inc. Method for processing adipose tissue and processing apparatus
US9206387B2 (en) 2010-07-09 2015-12-08 The Gid Group, Inc. Method and apparatus for processing adipose tissue
EP2593542B1 (de) 2010-07-13 2018-01-03 Anthrogenesis Corporation Verfahren zur erzeugung von natürlichen killerzellen
KR101851956B1 (ko) 2010-08-31 2018-04-25 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
BR112013004614A2 (pt) 2010-08-31 2024-01-16 Janssen Biotech Inc Diferenciação de células-tronco pluripotentes
WO2012030539A2 (en) 2010-08-31 2012-03-08 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
EP2625577B1 (de) 2010-10-08 2019-06-26 Terumo BCT, Inc. Anpassbares verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem
ES2384790B1 (es) * 2010-12-10 2013-05-20 Instituto De Salud Carlos Iii Células madre mesenquimales aisladas a partir de sangre periférica.
WO2012092485A1 (en) 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
US9164079B2 (en) 2011-03-17 2015-10-20 Greyledge Technologies Llc Systems for autologous biological therapeutics
EP3443968A1 (de) 2011-06-01 2019-02-20 Celularity, Inc. Schmerzbehandlung mithilfe von stammzellen aus der plazenta
CN104508124B (zh) 2011-07-06 2017-11-17 细胞治疗有限公司 中胚层谱系祖细胞
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
US20140341863A1 (en) * 2011-11-01 2014-11-20 Neostem, Inc. Adult mesenchymal stem cell (msc) compositions and methods for preparing the same
KR102203056B1 (ko) 2011-12-22 2021-01-14 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화
SG11201405052RA (en) 2012-03-07 2014-10-30 Janssen Biotech Inc Defined media for expansion and maintenance of pluripotent stem cells
CN108034633B (zh) 2012-06-08 2022-08-02 詹森生物科技公司 人胚胎干细胞向胰腺内分泌细胞的分化
BR112015004003B1 (pt) 2012-09-06 2020-05-19 The Gid Group Inc aparelho para processar material biológico humano contendo tecido fibroso e método para processar tecido adiposo
BR112015015714A2 (pt) 2012-12-31 2017-07-11 Janssen Biotech Inc suspensão e aglomeração de células pluripotentes humanas para diferenciação em célu-las endócrinas pancreáticas
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
EP2938724B1 (de) 2012-12-31 2020-10-28 Janssen Biotech, Inc. Kultivierung von menschlichen embryonalen stammzellen an der luft-flüssigkeitsgrenze zur differenzierung in endokrine pankreaszellen
AU2013368224B2 (en) 2012-12-31 2018-09-27 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into pancreatic endocrine cells using HB9 regulators
CN105142651A (zh) 2013-02-05 2015-12-09 人类起源公司 来自胎盘的自然杀伤细胞
EP3038629B1 (de) 2013-09-05 2020-11-18 GID BIO, Inc. Verfahren zur verarbeitung von fettgewebe
US20150093367A1 (en) * 2013-09-27 2015-04-02 Global Health Solutions Research Trust Acupoint injection therapy using an enriched cellular mixture
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
US10092711B2 (en) 2014-05-02 2018-10-09 Lifecell Corporation Injection sensor with feedback mechanism
EP3143127B1 (de) 2014-05-16 2021-07-14 Janssen Biotech, Inc. Verwendung kleiner moleküle zur verstärkung der mafa-expression in endokrinen pankreaszellen
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
BR112018008059A2 (pt) 2015-10-21 2018-10-23 Lifecell Corp sistemas e métodos para controle de dispositivo médico
AU2016342002A1 (en) 2015-10-21 2018-05-10 Lifecell Corporation Systems and methods for tube management
CA3008035A1 (en) 2015-12-22 2017-06-29 Lifecell Corporation Syringe filling device for fat transfer
EP3439610A4 (de) 2016-04-06 2019-12-18 University of Florida Research Foundation, Inc. Therapeutische verwendung von elektroakupunkturinduzierten mesenchymalen stammzellen
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CA3035193A1 (en) 2016-08-30 2018-03-08 Lifecell Corporation Systems and methods for medical device control
USD851777S1 (en) 2017-01-30 2019-06-18 Lifecell Corporation Canister-type device for tissue processing
EP3656841A1 (de) 2017-03-31 2020-05-27 Terumo BCT, Inc. Zellexpansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11613733B2 (en) * 2017-05-12 2023-03-28 Medical & Biological Laboratories Co., Ltd. Method for purifying mesenchymal stem cells to improve transplantation efficiency
EP3655518A4 (de) 2017-07-18 2021-07-14 GID Bio, Inc. System zur verdauung von fettgewebe und gewebeverarbeitungsverfahren
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5199942A (en) 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation

Also Published As

Publication number Publication date
EP1028737B1 (de) 2007-04-04
CA2294944A1 (en) 1999-01-14
WO1999001145A1 (en) 1999-01-14
EP1028737A4 (de) 2002-12-04
AU8476698A (en) 1999-01-25
US6261549B1 (en) 2001-07-17
EP1028737A1 (de) 2000-08-23
DE69837491T2 (de) 2008-01-17
CY1106798T1 (el) 2012-05-23
PT1028737E (pt) 2007-07-11
ES2285779T3 (es) 2007-11-16
DK1028737T3 (da) 2007-08-13
ATE358493T1 (de) 2007-04-15

Similar Documents

Publication Publication Date Title
DE69837491D1 (de) Menschliche mesenchymale stammzellen aus peripherem blut
NO20001509L (no) Dannelse av hematopoetiske celler fra multipotente neurale stam-celler
WO1999046366A8 (en) Uses for humane non-autologous mesenchymal stem cells
DE3887375D1 (de) Pflanzengewebe-Transformation.
ATE469654T1 (de) Verwendung des erythropoietins zur regeneration von lebergewebe
EP0871414A4 (de) Behandeltes gewebe zur implantation, sowie herstellungsverfahren
DE69941903D1 (de) Behandlung von patienten die eine knochenmarktransplantation oder eine transplantation peripherer blutstammzellen erhalten mit anti-cd20 antikörpern
MXPA02007137A (es) Fuente de tejido hepatico.
ES8704546A1 (es) Metodo de produccion de una proteina con actividad procoagu-lante del tipo de factor viii:c humano
ES2147720T3 (es) Factor de celulas madre.
ATE296875T1 (de) Verfahren zur herstellung von genetisch modifizierten cd34-negativen, adhärent wachsenden hämatopoietischen stammzellen
ATE300310T1 (de) Verfahren zur steigerung von hematopoietischen zellen
ATE397461T1 (de) Auf tgf-beta 1 ansprechende knochenmarkzellen
ATE348876T1 (de) Verfahren zur vermehrung von natürlichen killerzellen
PT941329E (pt) Metodo para prevenir a rejeicao de enxertos em transplantacao e para produzir uma celula-hospedeiro para terapia genetica universal utilizando activacao de linfocitos (lag-3)
WO2004011631A3 (en) Methods and compositions for treating tissue defects using pulsed electromagnetic field stimulus
ATE521696T1 (de) Verfahren zur herstellung von zelltransplantaten
ATE15693T1 (de) Zellkultur-verfahren.
PT1198557E (pt) Cultura melhorada de queeratinocito e suas utilizacoes
NO961031D0 (no) Fremgangsmåte til å drepe uönskede målceller
ATE191501T1 (de) Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen
ES8604774A1 (es) Procedimiento de preparar agentes cosmeticos para el trata- miento de la piel
DE3272969D1 (en) Anaerobic method for preserving whole blood, tissue and components containing living mammalian cells
DE69734349D1 (de) Behandlung von knochenleiden mit adrenomedullin
NO20022109D0 (no) Anvendelse av treosulfan for behandling av pasienter för benmargs- eller blodstamcelletansplantasjon

Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: DR. VOLKER VOSSIUS, CORINNA VOSSIUS, TILMAN VOSSIU

8364 No opposition during term of opposition