CN102741395B - 人胚胎干细胞的分化 - Google Patents
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Abstract
Description
Claims (17)
Applications Claiming Priority (3)
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US61/289671 | 2009-12-23 | ||
PCT/US2010/060756 WO2011079017A2 (en) | 2009-12-23 | 2010-12-16 | Differentiation of human embryonic stem cells |
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CN102741395A CN102741395A (zh) | 2012-10-17 |
CN102741395B true CN102741395B (zh) | 2016-03-16 |
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JP (2) | JP6392496B2 (zh) |
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CN (1) | CN102741395B (zh) |
AU (2) | AU2010333839C1 (zh) |
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MX (1) | MX343786B (zh) |
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SG (2) | SG181687A1 (zh) |
WO (1) | WO2011079017A2 (zh) |
ZA (1) | ZA201205487B (zh) |
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US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
CA3207103A1 (en) | 2007-07-31 | 2009-02-05 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to pancreatic endocrine |
WO2009070592A2 (en) | 2007-11-27 | 2009-06-04 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
KR20170001727A (ko) | 2008-02-21 | 2017-01-04 | 얀센 바이오테크 인코포레이티드 | 세포 부착, 배양 및 탈리를 위한 방법, 표면 개질 플레이트 및 조성물 |
CN102159703B (zh) | 2008-06-30 | 2015-11-25 | 森托科尔奥索生物科技公司 | 多能干细胞的分化 |
US9012218B2 (en) | 2008-10-31 | 2015-04-21 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
RU2522001C2 (ru) | 2008-10-31 | 2014-07-10 | Сентокор Орто Байотек Инк. | Дифференцирование человеческих эмбриональных стволовых клеток в линию панкреатических эндокринных клеток |
ES2667493T3 (es) | 2008-11-14 | 2018-05-11 | Viacyte, Inc. | Encapsulación de células pancreáticas derivadas de células madre humanas pluripotentes |
MX2011005289A (es) | 2008-11-20 | 2011-06-01 | Centocor Ortho Biotech Inc | Metodos y composiciones para union y cultivo celular sobre sustratos planares. |
KR101774546B1 (ko) | 2008-11-20 | 2017-09-04 | 얀센 바이오테크 인코포레이티드 | 마이크로-캐리어 상의 만능 줄기 세포 배양 |
US10076544B2 (en) | 2009-07-20 | 2018-09-18 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
US9150833B2 (en) | 2009-12-23 | 2015-10-06 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
KR101928299B1 (ko) | 2010-03-01 | 2018-12-12 | 얀센 바이오테크 인코포레이티드 | 만능 줄기 세포로부터 유래된 세포의 정제 방법 |
BR112012028855A2 (pt) | 2010-05-12 | 2015-09-22 | Janssen Biotech Inc | diferenciação das células-tronco embrionárias humanas |
AU2015268659B2 (en) * | 2010-05-12 | 2017-12-21 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
EP3372672A1 (en) | 2010-08-31 | 2018-09-12 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
SG10201506852VA (en) | 2010-08-31 | 2015-10-29 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
CN110016463A (zh) | 2010-11-15 | 2019-07-16 | 艾克塞利瑞提德生物技术公司 | 由人类滋养层干细胞生成神经干细胞 |
EP2723852B1 (en) | 2011-06-21 | 2021-11-17 | Novo Nordisk A/S | Efficient induction of definitive endoderm from pluripotent stem cells |
US20140234269A1 (en) * | 2011-07-22 | 2014-08-21 | Yale University | Endometrial Derived Stem Cells and Their Methods of Use |
CN105143446B (zh) | 2011-12-22 | 2020-11-03 | 詹森生物科技公司 | 人胚胎干细胞分化成单一激素胰岛素阳性细胞 |
AU2013230020B2 (en) | 2012-03-07 | 2018-08-09 | Janssen Biotech, Inc. | Defined media for expansion and maintenance of pluripotent stem cells |
CN108004199B (zh) * | 2012-04-30 | 2022-03-18 | 大学健康网络 | 用于从hPSC生成胰腺祖细胞和功能性β细胞的方法和组合物 |
KR102285014B1 (ko) * | 2012-06-08 | 2021-08-03 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 췌장 내분비 세포로의 분화 |
EP2893000B1 (en) | 2012-09-03 | 2019-04-10 | Novo Nordisk A/S | Generation of pancreatic endoderm from pluripotent stem cells using small molecules |
CN113604423A (zh) | 2012-11-30 | 2021-11-05 | 艾克塞利瑞提德生物技术公司 | 通过调节mir-124分化干细胞的方法 |
RU2768963C2 (ru) * | 2012-12-31 | 2022-03-25 | Янссен Байотек, Инк. | Культивация эмбриональных стволовых клеток человека в воздушно-жидкостной зоне взаимодействия с целью их дифференцировки в панкреатические эндокринные клетки |
CN105705634A (zh) | 2012-12-31 | 2016-06-22 | 詹森生物科技公司 | 用于分化成胰腺内分泌细胞的人多能细胞的悬浮和群集 |
US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
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