DK0935660T3 - Infektiöse kloner af RNA-virusser og vacciner og deraf afledte diagnostiske assays - Google Patents
Infektiöse kloner af RNA-virusser og vacciner og deraf afledte diagnostiske assaysInfo
- Publication number
- DK0935660T3 DK0935660T3 DK97954491T DK97954491T DK0935660T3 DK 0935660 T3 DK0935660 T3 DK 0935660T3 DK 97954491 T DK97954491 T DK 97954491T DK 97954491 T DK97954491 T DK 97954491T DK 0935660 T3 DK0935660 T3 DK 0935660T3
- Authority
- DK
- Denmark
- Prior art keywords
- vaccines
- diagnostic assays
- rna viruses
- genome
- infectious clones
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title abstract 5
- 241001493065 dsRNA viruses Species 0.000 title abstract 4
- 230000002458 infectious effect Effects 0.000 title abstract 4
- 238000003556 assay Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96203024A EP0839912A1 (fr) | 1996-10-30 | 1996-10-30 | Clones infectieux de virus à ARN, vaccins et essais diagnostiques |
PCT/NL1997/000593 WO1998018933A1 (fr) | 1996-10-30 | 1997-10-29 | Clones infectieux de virus a arn et vaccins et titrages de diagnostics derives de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0935660T3 true DK0935660T3 (da) | 2007-10-29 |
Family
ID=8224533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97954491T DK0935660T3 (da) | 1996-10-30 | 1997-10-29 | Infektiöse kloner af RNA-virusser og vacciner og deraf afledte diagnostiske assays |
Country Status (23)
Country | Link |
---|---|
US (5) | US6268199B1 (fr) |
EP (2) | EP0839912A1 (fr) |
JP (1) | JP3921552B2 (fr) |
KR (1) | KR100437254B1 (fr) |
CN (1) | CN1138859C (fr) |
AT (1) | ATE366314T1 (fr) |
AU (1) | AU719991B2 (fr) |
BR (1) | BR9712592A (fr) |
CA (1) | CA2272046C (fr) |
CZ (1) | CZ294781B6 (fr) |
DE (1) | DE69737886T2 (fr) |
DK (1) | DK0935660T3 (fr) |
ES (1) | ES2290973T3 (fr) |
HU (1) | HUP9903829A3 (fr) |
ID (1) | ID22208A (fr) |
MY (1) | MY117686A (fr) |
PL (1) | PL191258B1 (fr) |
PT (1) | PT935660E (fr) |
SI (1) | SI0935660T1 (fr) |
SK (1) | SK286231B6 (fr) |
UA (1) | UA72433C2 (fr) |
WO (1) | WO1998018933A1 (fr) |
ZA (1) | ZA979732B (fr) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0839912A1 (fr) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Clones infectieux de virus à ARN, vaccins et essais diagnostiques |
US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
EP0974660A1 (fr) * | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Clones infectieux du virus de la maladie de Newcastle, vaccins et analyses diagnostiqués |
CA2440933A1 (fr) | 1998-12-22 | 2000-06-22 | Pfizer Products Inc. | Un clone d'adnc infectieux du virus nord-americain du syndrome dysgenesique respiratoire porcin (sdrp) et ses utilisations |
US7618797B2 (en) | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
US7132106B2 (en) * | 1998-12-22 | 2006-11-07 | Pfizer Inc. | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
US7691389B2 (en) | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
CA2366072C (fr) | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Vaccins contre le virus du syndrome dysgenesique respiratoire porcin (srdp) |
CA2650236C (fr) | 1999-04-22 | 2016-01-12 | United States Of America, As Represented By The Secretary Of Agriculture | Vaccin contre le syndrome dysgenesique respiratoire porcin base sur l'isolat ja-142 |
KR20030032910A (ko) * | 2000-01-26 | 2003-04-26 | 베링거 인겔하임 베트메디카 게엠베하 | Prrsv의 재조합 약독화 |
EP1156111A1 (fr) * | 2000-05-19 | 2001-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Particules chimériques de type arterivirus |
DE50214200D1 (de) | 2001-06-05 | 2010-03-25 | Curevac Gmbh | Stabilisierte Tumorantigen-mRNA mit erhöhtem G/C-Gehalt |
DE10162480A1 (de) | 2001-12-19 | 2003-08-07 | Ingmar Hoerr | Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen |
US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
DE10229872A1 (de) * | 2002-07-03 | 2004-01-29 | Curevac Gmbh | Immunstimulation durch chemisch modifizierte RNA |
DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
RU2007101725A (ru) | 2004-06-18 | 2008-07-27 | Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) | Идентификация инфицированных вирусом и вакцинированных вирусом организмов |
KR100872840B1 (ko) | 2004-07-09 | 2008-12-22 | (주)씨아이디 | 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도 |
US20060020227A1 (en) * | 2004-07-20 | 2006-01-26 | Moore Thomas E | Collection means and a method for collecting cord blood |
US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
CN101189027A (zh) | 2005-01-13 | 2008-05-28 | 贝林格尔·英格海姆维特梅迪卡有限公司 | 改良的prrs疫苗 |
RU2381035C2 (ru) * | 2005-02-25 | 2010-02-10 | Пфайзер Продактс Инк. | Композиция для защиты свиней от инфекции ррсс-вируса (варианты) и вакцина, содержащая указанную композицию (варианты) |
SI1904631T1 (sl) | 2005-06-24 | 2012-09-28 | Univ Minnesota | Virusi PRRS, infekciozni kloni, njihovi mutanti in postopki uporabe |
KR20080064813A (ko) * | 2005-08-30 | 2008-07-09 | 보드 오브 리젠츠 오브 디 유니버시티 오브 네브라스카 | 면역원성이 증강된 prrsv 항원을 사용하는 동물의백신화 방법 및 조성물 |
DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
AU2007280690C1 (en) | 2006-07-31 | 2012-08-23 | Curevac Gmbh | Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant |
US7666585B2 (en) | 2007-06-15 | 2010-02-23 | Protatek International, Inc. | Construction of chimera PRRSV, compositions and vaccine preparations |
CN101454442A (zh) * | 2007-06-15 | 2009-06-10 | 普泰克国际有限公司 | 嵌合体prrsv的构建,组合物及疫苗的制备 |
CN101848995A (zh) * | 2007-06-25 | 2010-09-29 | 南达科他州立大学 | 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法 |
WO2009030254A1 (fr) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes d'arn et de peptides cationiques pour transfection et immunostimulation |
MX2010008468A (es) | 2008-01-31 | 2010-08-30 | Curevac Gmbh | Acidos nucleicos de la formula (i) (nug1xmgnnv)a y derivados de los mismos como un agente/adyuvante inmunoestimulante. |
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US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
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UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
JP2014506795A (ja) | 2011-02-17 | 2014-03-20 | ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング | Prrsvの工業規模の製造方法 |
UA117272C2 (uk) | 2011-02-17 | 2018-07-10 | Бьорінгер Інгельхайм Ветмедіка Гмбх | Новий європейський штам prrsv |
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WO2015062738A1 (fr) | 2013-11-01 | 2015-05-07 | Curevac Gmbh | Arn modifié à propriétés immunostimulantes réduites |
WO2015092058A1 (fr) | 2013-12-20 | 2015-06-25 | Boehringer Ingelheim Vetmedica Gmbh | Variant de virus de sdrp, clone d'adnc de virus de sdrp européen et leurs utilisations |
CA2936286A1 (fr) | 2014-04-01 | 2015-10-08 | Curevac Ag | Complexe cargo de support polymere a utiliser comme agent immunostimulant ou comme adjuvant |
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WO2016128060A1 (fr) | 2015-02-12 | 2016-08-18 | Biontech Ag | Prédiction des épitopes de lymphocytes t utiles pour la vaccination |
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WO2017059902A1 (fr) | 2015-10-07 | 2017-04-13 | Biontech Rna Pharmaceuticals Gmbh | Séquences utr 3' permettant la stabilisation d'arn |
EP3389706A1 (fr) | 2015-12-14 | 2018-10-24 | Boehringer Ingelheim Vetmedica, Inc. | Vaccins pour félins à noyaux hybrides |
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JP7129978B2 (ja) | 2016-12-14 | 2022-09-02 | ゾエティス・サービシーズ・エルエルシー | 豚繁殖・呼吸障害症候群(prrs)ウイルスの欧州株に対抗する離乳前の効果的なワクチン接種 |
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-
1996
- 1996-10-30 EP EP96203024A patent/EP0839912A1/fr not_active Withdrawn
-
1997
- 1997-10-29 AU AU58828/98A patent/AU719991B2/en not_active Expired
- 1997-10-29 ID IDW990271A patent/ID22208A/id unknown
- 1997-10-29 SI SI9730768T patent/SI0935660T1/sl unknown
- 1997-10-29 DK DK97954491T patent/DK0935660T3/da active
- 1997-10-29 MY MYPI97005141A patent/MY117686A/en unknown
- 1997-10-29 WO PCT/NL1997/000593 patent/WO1998018933A1/fr active IP Right Grant
- 1997-10-29 ZA ZA9709732A patent/ZA979732B/xx unknown
- 1997-10-29 CA CA2272046A patent/CA2272046C/fr not_active Expired - Lifetime
- 1997-10-29 EP EP97954491A patent/EP0935660B1/fr not_active Expired - Lifetime
- 1997-10-29 US US09/297,535 patent/US6268199B1/en not_active Expired - Lifetime
- 1997-10-29 PL PL333070A patent/PL191258B1/pl not_active IP Right Cessation
- 1997-10-29 PT PT97954491T patent/PT935660E/pt unknown
- 1997-10-29 JP JP52032198A patent/JP3921552B2/ja not_active Expired - Lifetime
- 1997-10-29 CN CNB97180706XA patent/CN1138859C/zh not_active Expired - Lifetime
- 1997-10-29 ES ES97954491T patent/ES2290973T3/es not_active Expired - Lifetime
- 1997-10-29 AT AT97954491T patent/ATE366314T1/de active
- 1997-10-29 HU HU9903829A patent/HUP9903829A3/hu unknown
- 1997-10-29 CZ CZ19991564A patent/CZ294781B6/cs not_active IP Right Cessation
- 1997-10-29 KR KR10-1999-7003788A patent/KR100437254B1/ko not_active IP Right Cessation
- 1997-10-29 UA UA99052951A patent/UA72433C2/uk unknown
- 1997-10-29 BR BR9712592-0A patent/BR9712592A/pt not_active Application Discontinuation
- 1997-10-29 DE DE69737886T patent/DE69737886T2/de not_active Expired - Lifetime
- 1997-10-29 SK SK547-99A patent/SK286231B6/sk not_active IP Right Cessation
-
2001
- 2001-06-05 US US09/874,626 patent/US20020098573A1/en not_active Abandoned
-
2003
- 2003-12-30 US US10/750,410 patent/US20040197872A1/en not_active Abandoned
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2005
- 2005-09-29 US US11/239,529 patent/US8546124B2/en not_active Expired - Fee Related
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