DK0642528T3 - Biologisk aktive forbindelser af phosphotriestertypen - Google Patents

Biologisk aktive forbindelser af phosphotriestertypen

Info

Publication number
DK0642528T3
DK0642528T3 DK93910147.3T DK93910147T DK0642528T3 DK 0642528 T3 DK0642528 T3 DK 0642528T3 DK 93910147 T DK93910147 T DK 93910147T DK 0642528 T3 DK0642528 T3 DK 0642528T3
Authority
DK
Denmark
Prior art keywords
biologically active
active compounds
radical
phosphotriester
type
Prior art date
Application number
DK93910147.3T
Other languages
English (en)
Inventor
Gilles Gosselin
Jean-Louis Imbach
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9206383A external-priority patent/FR2691463A1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0642528T3 publication Critical patent/DK0642528T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93910147.3T 1992-05-25 1993-05-24 Biologisk aktive forbindelser af phosphotriestertypen DK0642528T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206383A FR2691463A1 (fr) 1992-05-25 1992-05-25 Dérivés nucléotidiques, leur préparation et leur application en thérapeutique.
FR9304117A FR2692265B1 (fr) 1992-05-25 1993-04-07 Composes biologiquement actifs de type phosphotriesters.

Publications (1)

Publication Number Publication Date
DK0642528T3 true DK0642528T3 (da) 1997-07-21

Family

ID=26229484

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93910147.3T DK0642528T3 (da) 1992-05-25 1993-05-24 Biologisk aktive forbindelser af phosphotriestertypen

Country Status (11)

Country Link
US (2) US6399589B1 (da)
EP (1) EP0642528B1 (da)
JP (1) JP3628324B2 (da)
AT (1) ATE147750T1 (da)
CA (1) CA2136622C (da)
DE (1) DE69307506T2 (da)
DK (1) DK0642528T3 (da)
ES (1) ES2099436T3 (da)
FR (1) FR2692265B1 (da)
GR (1) GR3023130T3 (da)
WO (1) WO1993024510A1 (da)

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CA2136622A1 (fr) 1993-12-09
ES2099436T3 (es) 1997-05-16
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ATE147750T1 (de) 1997-02-15
US6399589B1 (en) 2002-06-04
US20020037873A1 (en) 2002-03-28
EP0642528B1 (fr) 1997-01-15
JP3628324B2 (ja) 2005-03-09
DE69307506T2 (de) 1997-07-03
FR2692265A1 (fr) 1993-12-17
DE69307506D1 (de) 1997-02-27
WO1993024510A1 (fr) 1993-12-09
EP0642528A1 (fr) 1995-03-15
CA2136622C (fr) 2006-01-03
US6555676B2 (en) 2003-04-29
JPH07507068A (ja) 1995-08-03
FR2692265B1 (fr) 1996-11-08

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