FI823923L - Antifibrinolytiskt aktiva foereningar - Google Patents

Antifibrinolytiskt aktiva foereningar

Info

Publication number
FI823923L
FI823923L FI823923A FI823923A FI823923L FI 823923 L FI823923 L FI 823923L FI 823923 A FI823923 A FI 823923A FI 823923 A FI823923 A FI 823923A FI 823923 L FI823923 L FI 823923L
Authority
FI
Finland
Prior art keywords
carbon atoms
image
groups containing
antifibrinolytiskt
aktiva
Prior art date
Application number
FI823923A
Other languages
English (en)
Other versions
FI73969C (fi
FI73969B (fi
FI823923A0 (fi
Inventor
Carl Magnus Erik Svahn
Ferenc Merenyi
Lennart Elof Karlsson
Gunnar Hanshoff
Original Assignee
Kabivitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabivitrum Ab filed Critical Kabivitrum Ab
Publication of FI823923A0 publication Critical patent/FI823923A0/fi
Publication of FI823923L publication Critical patent/FI823923L/fi
Application granted granted Critical
Publication of FI73969B publication Critical patent/FI73969B/fi
Publication of FI73969C publication Critical patent/FI73969C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Lubricants (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Materials For Medical Uses (AREA)
  • Compression Or Coding Systems Of Tv Signals (AREA)
  • Fats And Perfumes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI823923A 1981-11-17 1982-11-16 Foerfarande foer framstaellning av terapeutiskt aktiva trans-4-aminometylcyklohexankarboxylsyraderivat. FI73969C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8106818 1981-11-17
SE8106818 1981-11-17

Publications (4)

Publication Number Publication Date
FI823923A0 FI823923A0 (fi) 1982-11-16
FI823923L true FI823923L (fi) 1983-05-18
FI73969B FI73969B (fi) 1987-08-31
FI73969C FI73969C (fi) 1987-12-10

Family

ID=20345052

Family Applications (1)

Application Number Title Priority Date Filing Date
FI823923A FI73969C (fi) 1981-11-17 1982-11-16 Foerfarande foer framstaellning av terapeutiskt aktiva trans-4-aminometylcyklohexankarboxylsyraderivat.

Country Status (10)

Country Link
US (1) US4483867A (fi)
EP (1) EP0079872B1 (fi)
JP (1) JPS5892611A (fi)
AT (1) ATE12224T1 (fi)
CA (1) CA1202637A (fi)
DE (1) DE3262698D1 (fi)
DK (1) DK159148C (fi)
FI (1) FI73969C (fi)
HK (1) HK49688A (fi)
NO (1) NO160778C (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL67445A (en) * 1982-12-09 1985-11-29 Teva Pharma Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
EP0168043B1 (de) * 1984-07-11 1990-11-07 MERCK PATENT GmbH Flüssigkristall-Phase
FR2657257B1 (fr) * 1990-01-19 1994-09-02 Rhone Poulenc Sante Procede de preparation de medicaments sous forme de perles.
JPH0725724B2 (ja) * 1992-06-23 1995-03-22 財団法人生産開発科学研究所 トラネキサム酸亜鉛化合物
SE9300013L (sv) * 1992-12-30 1994-07-01 Kabi Pharmacia Ab Nytt förfarande och mellanprodukter för framställning av pro- läkemedel
US5720948A (en) * 1995-11-07 1998-02-24 Helene Curtis Inc. Non-ionic surfactant emulsion vehicles and their use for deposition of drug into and across skin
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
DE19943635A1 (de) * 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
KR20110097942A (ko) 2003-08-20 2011-08-31 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
WO2005066122A2 (en) 2003-12-30 2005-07-21 Xenoport, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US20090215898A1 (en) * 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050244495A1 (en) 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
JP4938771B2 (ja) 2005-06-20 2012-05-23 ゼノポート,インコーポレーテッド トラネキサム酸のカルバミン酸アシルオキシアルキルプロドラッグ、合成法、および使用
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
US20110060040A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
US20110184060A1 (en) 2010-01-22 2011-07-28 Xenoport, Inc. Oral dosage forms having a high loading of a tranexamic acid prodrug
CA2917604C (en) 2012-07-18 2021-08-10 Josune Orbe Lopategui New antifibrinolytic compounds
CN110621771A (zh) 2017-05-17 2019-12-27 国立研究开发法人农业·食品产业技术综合研究机构 Vitrigel膜干燥体的制造方法以及制造装置
CN108976146B (zh) * 2017-05-31 2020-11-27 首都医科大学 氨基正己酰氨甲环酰氨基正己酰芳香氨基酸,其合成,活性和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB949512A (en) * 1961-05-15 1964-02-12 Mitsubishi Chem Ind Pharmaceutical compositions containing 4-(aminomethyl)-cyclohexane-1-carboxylic acid
US3939200A (en) * 1966-01-06 1976-02-17 Rohm And Haas Company Aliphatic acyl-containing amine hydrochlorides
CA929942A (en) * 1968-10-14 1973-07-10 Okano Atsuji Esters and their production
US3995055A (en) * 1975-02-28 1976-11-30 Daiichi Seiyaku Co., Ltd. Method for treating peptic ulcers
GB1580783A (en) * 1978-04-27 1980-12-03 Daiichi Seiyaku Co Process for producing 4' - (2 - carboxyethyl)phenyl trans - 4 - aminomethyl-cyclohexanecarboxylate or the acid-additsalts thereof and intermediates for producing the same

Also Published As

Publication number Publication date
DE3262698D1 (en) 1985-04-25
NO160778C (no) 1989-05-31
FI73969C (fi) 1987-12-10
FI73969B (fi) 1987-08-31
JPH0326183B2 (fi) 1991-04-10
NO823836L (no) 1983-05-18
EP0079872B1 (en) 1985-03-20
DK159148B (da) 1990-09-10
ATE12224T1 (de) 1985-04-15
US4483867A (en) 1984-11-20
JPS5892611A (ja) 1983-06-02
FI823923A0 (fi) 1982-11-16
NO160778B (no) 1989-02-20
CA1202637A (en) 1986-04-01
DK159148C (da) 1991-02-11
DK509382A (da) 1983-05-18
HK49688A (en) 1988-07-15
EP0079872A1 (en) 1983-05-25

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Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: PHARMACIA AB

MA Patent expired

Owner name: PHARMACIA AB