DK0633893T3 - 17-Substituerede steroider, der er nyttige ved cancerbehandling - Google Patents

17-Substituerede steroider, der er nyttige ved cancerbehandling

Info

Publication number
DK0633893T3
DK0633893T3 DK93906670T DK93906670T DK0633893T3 DK 0633893 T3 DK0633893 T3 DK 0633893T3 DK 93906670 T DK93906670 T DK 93906670T DK 93906670 T DK93906670 T DK 93906670T DK 0633893 T3 DK0633893 T3 DK 0633893T3
Authority
DK
Denmark
Prior art keywords
carbon atoms
beta
hydrogen atom
pyridyl
alkyl
Prior art date
Application number
DK93906670T
Other languages
Danish (da)
English (en)
Inventor
Susan Elaine Barrie
Michael Jarman
Gerard Andrew Potter
Original Assignee
Btg Int Ltd
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26300621&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0633893(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB929207057A external-priority patent/GB9207057D0/en
Priority claimed from GB929224880A external-priority patent/GB9224880D0/en
Application filed by Btg Int Ltd, British Tech Group filed Critical Btg Int Ltd
Application granted granted Critical
Publication of DK0633893T3 publication Critical patent/DK0633893T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
DK93906670T 1992-03-31 1993-03-15 17-Substituerede steroider, der er nyttige ved cancerbehandling DK0633893T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929207057A GB9207057D0 (en) 1992-03-31 1992-03-31 Steroids
GB929224880A GB9224880D0 (en) 1992-11-27 1992-11-27 Steroids
PCT/GB1993/000531 WO1993020097A1 (en) 1992-03-31 1993-03-15 17-substituted steroids useful in cancer treatment

Publications (1)

Publication Number Publication Date
DK0633893T3 true DK0633893T3 (da) 2000-04-17

Family

ID=26300621

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93906670T DK0633893T3 (da) 1992-03-31 1993-03-15 17-Substituerede steroider, der er nyttige ved cancerbehandling

Country Status (16)

Country Link
EP (1) EP0633893B1 (ko)
JP (1) JP2742331B2 (ko)
KR (1) KR100235135B1 (ko)
AT (1) ATE186913T1 (ko)
AU (1) AU668144B2 (ko)
CA (1) CA2132449C (ko)
CZ (1) CZ287434B6 (ko)
DE (2) DE69327096T2 (ko)
DK (1) DK0633893T3 (ko)
ES (1) ES2138618T3 (ko)
GB (1) GB2265624B (ko)
IL (1) IL105078A (ko)
LU (1) LU91911I2 (ko)
MX (1) MX9301525A (ko)
NZ (1) NZ249911A (ko)
WO (1) WO1993020097A1 (ko)

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CN103059090B (zh) * 2011-10-20 2016-06-22 连云港润众制药有限公司 醋酸阿比特龙草酸盐以及醋酸阿比特龙的纯化方法
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CN103254265B (zh) 2012-02-21 2016-07-13 上海希迈医药科技有限公司 醋酸阿比特龙三氟乙酸盐及其制备方法和应用
CN102627681B (zh) * 2012-03-23 2016-04-13 山东新时代药业有限公司 一种醋酸阿比特龙的制备方法
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US9512169B2 (en) * 2012-07-10 2016-12-06 Bayer Pharma Aktiengesellschaft 3-substituted estra-1,3,5(10),16-tetraene derivatives, methods for the production thereof, pharmaceutical preparations containing same, and use thereof for the production of medicaments
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WO2014009436A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Nanosuspension of abiraterone acetate
WO2014009437A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Oxidation stability of abiraterone acetate
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WO2014058785A1 (en) 2012-10-10 2014-04-17 Novartis Ag Combination therapy
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WO2014071983A1 (en) 2012-11-09 2014-05-15 Synthon Bv Process for making the 17-triflate intermediate of abiraterone-3-acetate
WO2014071984A1 (en) 2012-11-09 2014-05-15 Synthon Bv Process for making abiraterone-3-acetate
TWI570131B (zh) * 2012-11-13 2017-02-11 賽克系統公司 製備17-經取代類固醇之方法
WO2014075978A1 (en) 2012-11-16 2014-05-22 Synthon B.V. Process for the production of abiraterone-3-acetate involving an enol trliflation reaction in the presence of an alkoxy-pyridine compound
CN103059091B (zh) * 2012-11-22 2017-04-19 常州靶点医药科技有限公司 一种避免重金属残留的醋酸阿比特龙的制备方法
CN103864878A (zh) * 2012-12-12 2014-06-18 天津大学 阿比特龙醋酸酯的制备方法
EP2938625B1 (en) 2012-12-31 2018-02-21 Hetero Research Foundation Process for the preparation of abiraterone acetate
US20160022606A1 (en) 2013-03-14 2016-01-28 Pellficure Pharmaceuticals Inc. Novel therapy for prostate carcinoma
BR112015023098A2 (pt) 2013-03-14 2017-07-18 Univ Jefferson agentes de infrarregulação do receptor de andrógeno e usos dos mesmos
ES2612780T3 (es) 2013-04-19 2017-05-18 Zach System Proceso para producir una forma sólida de acetato de abiraterona
EP3013844A4 (en) * 2013-06-24 2017-03-01 Sun Pharmaceutical Industries LTD Process for preparation of abiraterone acetate
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CN104558091B (zh) * 2013-10-16 2017-07-28 天津金耀集团有限公司 一种醋酸阿比特龙的合成方法
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Also Published As

Publication number Publication date
GB2265624A (en) 1993-10-06
CZ233794A3 (en) 1995-02-15
KR950700923A (ko) 1995-02-20
JP2742331B2 (ja) 1998-04-22
CA2132449A1 (en) 1993-10-14
NZ249911A (en) 1996-06-25
CA2132449C (en) 2002-09-10
AU668144B2 (en) 1996-04-26
ATE186913T1 (de) 1999-12-15
CZ287434B6 (en) 2000-11-15
GB9305269D0 (en) 1993-05-05
EP0633893B1 (en) 1999-11-24
JPH07505377A (ja) 1995-06-15
DE69327096T2 (de) 2000-06-21
IL105078A0 (en) 1993-07-08
DE122012000012I1 (de) 2012-06-14
ES2138618T3 (es) 2000-01-16
KR100235135B1 (ko) 2000-01-15
EP0633893A1 (en) 1995-01-18
DE69327096D1 (de) 1999-12-30
MX9301525A (es) 1994-02-28
AU3758493A (en) 1993-11-08
GB2265624B (en) 1995-04-19
IL105078A (en) 1997-11-20
WO1993020097A1 (en) 1993-10-14
LU91911I2 (fr) 2012-02-07

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