DE69327096D1 - 17-substituierte steroide, verwendbar bei behandlung von krebs - Google Patents

17-substituierte steroide, verwendbar bei behandlung von krebs

Info

Publication number
DE69327096D1
DE69327096D1 DE69327096T DE69327096T DE69327096D1 DE 69327096 D1 DE69327096 D1 DE 69327096D1 DE 69327096 T DE69327096 T DE 69327096T DE 69327096 T DE69327096 T DE 69327096T DE 69327096 D1 DE69327096 D1 DE 69327096D1
Authority
DE
Germany
Prior art keywords
carbon atoms
beta
hydrogen atom
pyridyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69327096T
Other languages
English (en)
Other versions
DE69327096T2 (de
Inventor
Susan Elaine Barrie
Michael Jarman
Gerard Andrew Potter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
BTG International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26300621&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69327096(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB929207057A external-priority patent/GB9207057D0/en
Priority claimed from GB929224880A external-priority patent/GB9224880D0/en
Application filed by BTG International Ltd filed Critical BTG International Ltd
Application granted granted Critical
Publication of DE69327096D1 publication Critical patent/DE69327096D1/de
Publication of DE69327096T2 publication Critical patent/DE69327096T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69327096T 1992-03-31 1993-03-15 17-substituierte steroide, verwendbar bei behandlung von krebs Expired - Lifetime DE69327096T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929207057A GB9207057D0 (en) 1992-03-31 1992-03-31 Steroids
GB929224880A GB9224880D0 (en) 1992-11-27 1992-11-27 Steroids
PCT/GB1993/000531 WO1993020097A1 (en) 1992-03-31 1993-03-15 17-substituted steroids useful in cancer treatment

Publications (2)

Publication Number Publication Date
DE69327096D1 true DE69327096D1 (de) 1999-12-30
DE69327096T2 DE69327096T2 (de) 2000-06-21

Family

ID=26300621

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69327096T Expired - Lifetime DE69327096T2 (de) 1992-03-31 1993-03-15 17-substituierte steroide, verwendbar bei behandlung von krebs
DE201212000012 Pending DE122012000012I1 (de) 1992-03-31 2012-01-12 17-Substituierte steroide, verwendbar bei behandlung von krebs.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE201212000012 Pending DE122012000012I1 (de) 1992-03-31 2012-01-12 17-Substituierte steroide, verwendbar bei behandlung von krebs.

Country Status (16)

Country Link
EP (1) EP0633893B1 (de)
JP (1) JP2742331B2 (de)
KR (1) KR100235135B1 (de)
AT (1) ATE186913T1 (de)
AU (1) AU668144B2 (de)
CA (1) CA2132449C (de)
CZ (1) CZ287434B6 (de)
DE (2) DE69327096T2 (de)
DK (1) DK0633893T3 (de)
ES (1) ES2138618T3 (de)
GB (1) GB2265624B (de)
IL (1) IL105078A (de)
LU (1) LU91911I2 (de)
MX (1) MX9301525A (de)
NZ (1) NZ249911A (de)
WO (1) WO1993020097A1 (de)

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EP1344777B1 (de) 2000-11-20 2011-03-16 Takeda Pharmaceutical Company Limited Imidazolderivate, verfahren zu deren herstellung und deren verwendung
EP1348706B1 (de) 2000-12-08 2009-08-19 Takeda Pharmaceutical Company Limited Substituierte thiazolderivate mit 3-pyridylgruppen, verfahren zu deren herstellung und deren verwendung
CA2470214A1 (en) * 2001-12-13 2003-06-26 Abbott Laboratories 3-(phenyl-alkoxy)-5-(phenyl)-pyridine derivatives and related compounds as kinase inhibitors for the treatment of cancer
EP2298315A1 (de) * 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutische Behandlungsmethoden
US8569275B2 (en) 2002-08-28 2013-10-29 Harbor Therapeutics, Inc. Steroids having 7-oxgen and 17-heteroaryl substitution
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TWI570131B (zh) * 2012-11-13 2017-02-11 賽克系統公司 製備１７－經取代類固醇之方法
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Also Published As

Publication number Publication date
EP0633893A1 (de) 1995-01-18
CZ233794A3 (en) 1995-02-15
CZ287434B6 (en) 2000-11-15
IL105078A0 (en) 1993-07-08
DK0633893T3 (da) 2000-04-17
KR100235135B1 (ko) 2000-01-15
GB9305269D0 (en) 1993-05-05
JPH07505377A (ja) 1995-06-15
JP2742331B2 (ja) 1998-04-22
GB2265624A (en) 1993-10-06
ES2138618T3 (es) 2000-01-16
AU668144B2 (en) 1996-04-26
EP0633893B1 (de) 1999-11-24
MX9301525A (es) 1994-02-28
CA2132449C (en) 2002-09-10
NZ249911A (en) 1996-06-25
KR950700923A (ko) 1995-02-20
DE69327096T2 (de) 2000-06-21
AU3758493A (en) 1993-11-08
WO1993020097A1 (en) 1993-10-14
CA2132449A1 (en) 1993-10-14
DE122012000012I1 (de) 2012-06-14
GB2265624B (en) 1995-04-19
IL105078A (en) 1997-11-20
LU91911I2 (fr) 2012-02-07
ATE186913T1 (de) 1999-12-15

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