TW343976B - 17-substituted steroids useful in cancer treatment - Google Patents

17-substituted steroids useful in cancer treatment

Info

Publication number
TW343976B
TW343976B TW082102024A TW82102024A TW343976B TW 343976 B TW343976 B TW 343976B TW 082102024 A TW082102024 A TW 082102024A TW 82102024 A TW82102024 A TW 82102024A TW 343976 B TW343976 B TW 343976B
Authority
TW
Taiwan
Prior art keywords
androst
ene
androstan
dien
androsta
Prior art date
Application number
TW082102024A
Other languages
Chinese (zh)
Inventor
Elaine Barrie Susan
Jarman Michael
Andrew Potter Gerard
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Application granted granted Critical
Publication of TW343976B publication Critical patent/TW343976B/en

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  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of the formula (I) (formula I) in which R represents a hydrogen atom or an alkyl group of 1-4 carbon atoms, in the form of the free bases or pharmaceutically acceptable acid addition salts, but excluding 3β-methoxy-17-(3-pyridyl)-5α-androst-16-ene; X represents the residue selected from the group consisting of androstan-3α- or 3β-ol, androst-5-en-3α- or 3β-ol, androst-4-en-3-one, androst-2-ene, androst-4-ene, androst-5-ene, androsta-5,7-dien-3α or 3β-ol, androsta-1,4-dien-3-one, androsta-3,5-dien, estra-1,3,5[10]-triene, estra-1,3,5[10]-trien-3-ol, 5α-androstan-3-one, androst-4-ene-3,11-dione, 6-fluoroandrost-4-ene-3-one, androstan-4-ene-3,6-dione, androstan-3,5-dien-3-ol, each of which, where structurally permissible, can be further derivatised in one or more of the following ways: to form 3-esters to form 3-oximes to form desoxy derivatives to have one or more hydroxy, halo, trifluoro-methyl, C1-4 -acyloxy, oxo substituents in the A, B, or C-ring.
TW082102024A 1992-03-31 1993-03-19 17-substituted steroids useful in cancer treatment TW343976B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929207057A GB9207057D0 (en) 1992-03-31 1992-03-31 Steroids

Publications (1)

Publication Number Publication Date
TW343976B true TW343976B (en) 1998-11-01

Family

ID=10713204

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082102024A TW343976B (en) 1992-03-31 1993-03-19 17-substituted steroids useful in cancer treatment

Country Status (2)

Country Link
GB (1) GB9207057D0 (en)
TW (1) TW343976B (en)

Also Published As

Publication number Publication date
GB9207057D0 (en) 1992-05-13

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