ES8707518A1 - Un procedimiento para preparar nuevos derivados del 1,3-ben-zoxatiol - Google Patents

Un procedimiento para preparar nuevos derivados del 1,3-ben-zoxatiol

Info

Publication number
ES8707518A1
ES8707518A1 ES550871A ES550871A ES8707518A1 ES 8707518 A1 ES8707518 A1 ES 8707518A1 ES 550871 A ES550871 A ES 550871A ES 550871 A ES550871 A ES 550871A ES 8707518 A1 ES8707518 A1 ES 8707518A1
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
alkyl group
alkoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550871A
Other languages
English (en)
Other versions
ES550871A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES550871A0 publication Critical patent/ES550871A0/es
Publication of ES8707518A1 publication Critical patent/ES8707518A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DEL 1,3-BENZOXATIOL, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), CON UN COMPUESTO DE FORMULA GENERAL (III), EN LAS QUE R1 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO; R2 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO O UN GRUPO ALQUENILO; R3 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO; R4 REPRESENTA UN GRUPO HIDROXI O UN GRUPO ACILOXI; R6 REPRESENTA UN ATOMO DE HIDROGENO; N ES 0, 1 O 2; Y Z ES UN RADICAL. DEL COMPUESTO OBTENIDO SE PUEDEN SEPARAR LOS GRUPOS PROTECTORES, OXIDAR EL AZUFRE Y SOMETER A REACCIONES DE INTERCAMBIO LOS GRUPOS SUSTITUYENTES Y SALIFICAR EL PRODUCTO OBTENIDO. DE APLICACION EN EL TRATAMIENTO DE TRASTORNOS CIRCULATORIOS Y ALERGIAS.
ES550871A 1984-03-28 1986-01-14 Un procedimiento para preparar nuevos derivados del 1,3-ben-zoxatiol Expired ES8707518A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59060198A JPS60226873A (ja) 1984-03-28 1984-03-28 １，３−ベンゾオキサチオ−ル誘導体及びその製法

Publications (2)

Publication Number Publication Date
ES550871A0 ES550871A0 (es) 1987-08-01
ES8707518A1 true ES8707518A1 (es) 1987-08-01

Family

ID=13135214

Family Applications (2)

Application Number Title Priority Date Filing Date
ES541698A Expired ES8701749A1 (es) 1984-03-28 1985-03-28 Un procedimiento para preparar nuevos derivados del 1,3-benzo-xatiol.
ES550871A Expired ES8707518A1 (es) 1984-03-28 1986-01-14 Un procedimiento para preparar nuevos derivados del 1,3-ben-zoxatiol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES541698A Expired ES8701749A1 (es) 1984-03-28 1985-03-28 Un procedimiento para preparar nuevos derivados del 1,3-benzo-xatiol.

Country Status (7)

Country Link
US (2) US4691027A (es)
EP (1) EP0157603B1 (es)
JP (1) JPS60226873A (es)
AT (1) ATE46156T1 (es)
CA (1) CA1243323A (es)
DE (1) DE3572814D1 (es)
ES (2) ES8701749A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016799D0 (en) * 1990-07-31 1990-09-12 Shell Int Research Pesticidal heterocyclic compounds
US5384411A (en) * 1991-06-20 1995-01-24 Hewlett-Packard Company Immobilization of PH-sensitive dyes to solid supports
CZ289317B6 (cs) * 1994-04-11 2002-01-16 Sankyo Company Limited Heterocyklická sloučenina, farmaceutický prostředek ji obsahující a její pouľití
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US20080258002A1 (en) * 2007-04-20 2008-10-23 Migliaccio Joseph J Hand Held Toilet Tissue Dispenser
KR20190015535A (ko) * 2016-06-09 2019-02-13 프라마나 파마슈티컬스 인크. 벤조[d][1,3]옥사티올, 벤조[d][1,3]옥사티올 3-옥사이드 또는 벤조[d][1,3]옥사티올 3,3-디옥사이드를 함유하는 화합물 및 Ｇ 단백질 커플링된 수용체 119의 작용제로서 이의 방법/용도
US11358956B2 (en) 2017-11-30 2022-06-14 Pramana Pharmaceuticals Inc. Compounds containing polysubstituted benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1259054A (es) * 1970-04-21 1972-01-05
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法

Also Published As

Publication number Publication date
EP0157603A3 (en) 1986-09-03
EP0157603A2 (en) 1985-10-09
JPS60226873A (ja) 1985-11-12
EP0157603B1 (en) 1989-09-06
ATE46156T1 (de) 1989-09-15
ES550871A0 (es) 1987-08-01
ES541698A0 (es) 1986-12-01
JPH0481589B2 (es) 1992-12-24
US4691027A (en) 1987-09-01
CA1243323A (en) 1988-10-18
ES8701749A1 (es) 1986-12-01
DE3572814D1 (en) 1989-10-12
US4871762A (en) 1989-10-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403