ES8505917A1 - Procedimiento para preparar derivados del acido acrilico - Google Patents

Procedimiento para preparar derivados del acido acrilico

Info

Publication number
ES8505917A1
ES8505917A1 ES535566A ES535566A ES8505917A1 ES 8505917 A1 ES8505917 A1 ES 8505917A1 ES 535566 A ES535566 A ES 535566A ES 535566 A ES535566 A ES 535566A ES 8505917 A1 ES8505917 A1 ES 8505917A1
Authority
ES
Spain
Prior art keywords
oxygen
acrylic acid
therapeutic
new compounds
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535566A
Other languages
English (en)
Other versions
ES535566A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19249/83A external-priority patent/IT1193615B/it
Priority claimed from IT22647/83A external-priority patent/IT1169782B/it
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES535566A0 publication Critical patent/ES535566A0/es
Publication of ES8505917A1 publication Critical patent/ES8505917A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEIDMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO ACRILICO Y DE SUS SALES ALCALINAS, ALCALINOTERREAS O AMONICAS, EN LAS FORMAS ESTEREOISOMERAS POSIBLES O DE MEZCLAS, DE FORMULA (I), EN LA QUE A Y B FORMAN UN DOBLE ENLACE C-C; Y R Y RK PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA RH, EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON ANHIDRIDO MALEICO. LA REACCION SE EFECTUA EN PRESENCIA DE CLORURO DE ALUMINIO COMO CATALIZADOR.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIULCEROSA, ANTISECRETORA GASTRICA Y CITOPROTECTORA.
ES535566A 1983-01-24 1984-08-31 Procedimiento para preparar derivados del acido acrilico Expired ES8505917A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19249/83A IT1193615B (it) 1983-01-24 1983-01-24 Derivati dell'acido acrilico che comprendono un eterociclo contenente ossigeno quali medicinali,prodotti industriali e procedimento di preparazione
IT22647/83A IT1169782B (it) 1983-08-25 1983-08-25 Derivati dell'acido acrilico che contengono un ciclo ossazolico oppure isossazolico, loro procedimento di preparazione e loro applicazione come farmaco

Publications (2)

Publication Number Publication Date
ES535566A0 ES535566A0 (es) 1985-06-16
ES8505917A1 true ES8505917A1 (es) 1985-06-16

Family

ID=26327109

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529073A Granted ES529073A0 (es) 1983-01-24 1984-01-23 Procedimiento para preparar derivados del acido acrilico
ES535566A Expired ES8505917A1 (es) 1983-01-24 1984-08-31 Procedimiento para preparar derivados del acido acrilico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529073A Granted ES529073A0 (es) 1983-01-24 1984-01-23 Procedimiento para preparar derivados del acido acrilico

Country Status (12)

Country Link
US (2) US4694019A (es)
CA (1) CA1244040A (es)
CH (1) CH661510A5 (es)
DE (1) DE3402313A1 (es)
ES (2) ES529073A0 (es)
FI (1) FI81793C (es)
FR (1) FR2546888B1 (es)
GB (1) GB2139216B (es)
HU (1) HU187982B (es)
LU (1) LU85178A1 (es)
NL (1) NL8400217A (es)
SE (1) SE454355B (es)

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB532822A (en) * 1939-08-11 1941-01-31 John David Kendall Improvements in and relating to the production of ª‡-coumarilyl and ª‡-thionaphthenoyl-acetic acid esters
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
NL6717403A (es) * 1966-12-30 1968-07-01
GR37790B (el) * 1966-12-30 1969-07-15 F. Hoffmann - La Roche & Co. Aktiengesellschaft Μεθοδος δια την παρασκευην παραγωγων του αρουλακρυλικου οξεος.
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
CH591415A5 (en) * 1972-09-13 1977-09-15 Takeda Chemical Industries Ltd 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder
FR2270856B1 (es) * 1974-01-17 1978-07-21 Screen
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
JPS5536434A (en) * 1978-09-07 1980-03-14 Sankyo Co Ltd 4-phenyl-4-oxo-2-butenoic acid derivative and its preparation
CA1156236A (en) * 1979-10-25 1983-11-01 George C. Rovnyak Mercaptoacyldihydropyrazole carboxylic acid derivatives
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique
IT1171604B (it) * 1981-10-22 1987-06-10 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione

Also Published As

Publication number Publication date
SE454355B (sv) 1988-04-25
GB8401739D0 (en) 1984-02-29
FI81793B (fi) 1990-08-31
CH661510A5 (fr) 1987-07-31
ES535566A0 (es) 1985-06-16
US4694019A (en) 1987-09-15
FR2546888B1 (fr) 1987-01-23
US4814348A (en) 1989-03-21
SE8306884L (sv) 1984-07-25
FI840269A (fi) 1984-07-25
SE8306884D0 (sv) 1983-12-13
HU187982B (en) 1986-03-28
FI81793C (fi) 1990-12-10
DE3402313A1 (de) 1984-07-26
FI840269A0 (fi) 1984-01-23
GB2139216A (en) 1984-11-07
ES8507560A1 (es) 1985-09-01
CA1244040A (fr) 1988-11-01
LU85178A1 (fr) 1984-10-24
NL8400217A (nl) 1984-08-16
GB2139216B (en) 1986-07-16
ES529073A0 (es) 1985-09-01
FR2546888A1 (fr) 1984-12-07

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506