IT1171604B - Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione - Google Patents

Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione

Info

Publication number
IT1171604B
IT1171604B IT49547/81A IT4954781A IT1171604B IT 1171604 B IT1171604 B IT 1171604B IT 49547/81 A IT49547/81 A IT 49547/81A IT 4954781 A IT4954781 A IT 4954781A IT 1171604 B IT1171604 B IT 1171604B
Authority
IT
Italy
Prior art keywords
ossobuten
fenyl
acid derivatives
pharmacological properties
preparation procedure
Prior art date
Application number
IT49547/81A
Other languages
English (en)
Other versions
IT8149547A0 (it
IT8149547A1 (it
Inventor
Mario Bianchi
Fernando Barzaghi
Original Assignee
Roussel Maestretti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti Spa filed Critical Roussel Maestretti Spa
Publication of IT8149547A0 publication Critical patent/IT8149547A0/it
Priority to IT49547/81A priority Critical patent/IT1171604B/it
Priority to SE8205867A priority patent/SE453831B/sv
Priority to US06/435,464 priority patent/US4500731A/en
Priority to NL8204062A priority patent/NL8204062A/nl
Priority to CH6132/82A priority patent/CH655924A5/fr
Priority to BE0/209294A priority patent/BE894765A/fr
Priority to CA000413892A priority patent/CA1189520A/fr
Priority to LU84428A priority patent/LU84428A1/fr
Priority to FR8217620A priority patent/FR2515175B1/fr
Priority to JP57184809A priority patent/JPS5879950A/ja
Priority to AT0388682A priority patent/AT391689B/de
Priority to GB08230213A priority patent/GB2107714B/en
Priority to DE19823239156 priority patent/DE3239156A1/de
Publication of IT8149547A1 publication Critical patent/IT8149547A1/it
Application granted granted Critical
Publication of IT1171604B publication Critical patent/IT1171604B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
IT49547/81A 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione IT1171604B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT49547/81A IT1171604B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione
SE8205867A SE453831B (sv) 1981-10-22 1982-10-15 Nya 4-fenyl-4-oxo-2-butensyraderivat, deras salter, framstellning derav samt farmaceutiska kompositioner innehallande dem
US06/435,464 US4500731A (en) 1981-10-22 1982-10-20 Derivatives of 4-phenyl-4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and therapeutic uses for them
CA000413892A CA1189520A (fr) 1981-10-22 1982-10-21 Procede de preparation de nouveaux derives de l'acide 4-phenyl-4-oxo-2-butenoique et de leurs sels
CH6132/82A CH655924A5 (fr) 1981-10-22 1982-10-21 Derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, medicaments et compositions les renfermant.
BE0/209294A BE894765A (fr) 1981-10-22 1982-10-21 Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant
NL8204062A NL8204062A (nl) 1981-10-22 1982-10-21 Derivaten van 4-fenyl-4-oxo-2-buteenzuur en zouten daarvan, farmaceutische preparaten op basis daarvan en werkwijze voor het bereiden van een en ander.
LU84428A LU84428A1 (fr) 1981-10-22 1982-10-21 Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique,leurs sels,leur preparation,leur application comme medicaments et les compositions les renfermant
FR8217620A FR2515175B1 (fr) 1981-10-22 1982-10-21 Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant
JP57184809A JPS5879950A (ja) 1981-10-22 1982-10-22 ４−フエニル−４−オキソ−２−ブテン酸の新誘導体及びそれらの塩、これらの製造法、薬剤としての使用並びにそれを含有する組成物
AT0388682A AT391689B (de) 1981-10-22 1982-10-22 Verfahren zur herstellung von neuen 4-phenyl-4-oxo-2-butensaeurederivaten und von deren salzen
GB08230213A GB2107714B (en) 1981-10-22 1982-10-22 Phenyl ketones
DE19823239156 DE3239156A1 (de) 1981-10-22 1982-10-22 Neue 4-phenyl-4-oxo-2-butensaeure-derivate, deren salze, deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden zusammensetzungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49547/81A IT1171604B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione

Publications (3)

Publication Number Publication Date
IT8149547A0 IT8149547A0 (it) 1981-10-22
IT8149547A1 IT8149547A1 (it) 1983-04-22
IT1171604B true IT1171604B (it) 1987-06-10

Family

ID=11270988

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49547/81A IT1171604B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione

Country Status (13)

Country Link
US (1) US4500731A (it)
JP (1) JPS5879950A (it)
AT (1) AT391689B (it)
BE (1) BE894765A (it)
CA (1) CA1189520A (it)
CH (1) CH655924A5 (it)
DE (1) DE3239156A1 (it)
FR (1) FR2515175B1 (it)
GB (1) GB2107714B (it)
IT (1) IT1171604B (it)
LU (1) LU84428A1 (it)
NL (1) NL8204062A (it)
SE (1) SE453831B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454355B (sv) * 1983-01-24 1988-04-25 Roussel Uclaf Akrylsyraderivat innehallande en furyl-, pyranyl-, bensofuranyl-, oxazolyl- eller isoxazolylgrupp, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat
JPH0641440B2 (ja) * 1985-06-05 1994-06-01 鐘淵化学工業株式会社 トランス−β−ベンゾイルアクリル酸エステルの製造法
IL79280A (en) * 1985-07-05 1990-07-12 Smith Kline French Lab 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them
IT1190340B (it) * 1986-06-06 1988-02-16 Roussel Maestretti Spa Derivati dell'acido 4-fenil 4-osso 2-butenoico,loro procedimento di preparazione e loro impiego come prodotti medicinali
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater
US5216024A (en) * 1987-07-28 1993-06-01 Baylor College Of Medicine Cell growth inhibitors and methods of treating cancer and cell proliferative diseases
HU198292B (en) * 1987-09-25 1989-09-28 Richter Gedeon Vegyeszet Process for producing salicilates and pharmaceutical compositions comprising such active ingredient
JPH04235142A (ja) * 1991-01-09 1992-08-24 Kanegafuchi Chem Ind Co Ltd トランス−β−アロイルアクリル酸エステル類の製造法
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent
KR101059776B1 (ko) * 2001-06-12 2011-08-26 웰스테트 테라퓨틱스 코포레이션 대사 질환의 치료용 화합물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6717403A (it) * 1966-12-30 1968-07-01
BE758462A (fr) * 1969-11-04 1971-05-04 Basf Ag Procede pour l'obtention de composes carbonyles beta-hydroxy etalpha-non satures
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
CH591415A5 (en) * 1972-09-13 1977-09-15 Takeda Chemical Industries Ltd 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder
FR2300551A2 (fr) * 1975-02-17 1976-09-10 Fabre Sa Pierre Nouveaux
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique
FR2504005A2 (fr) * 1980-04-24 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide 4-phenyl 4-oxo-2-butenoique

Also Published As

Publication number Publication date
NL8204062A (nl) 1983-05-16
SE8205867D0 (sv) 1982-10-15
CH655924A5 (fr) 1986-05-30
GB2107714A (en) 1983-05-05
AT391689B (de) 1990-11-12
IT8149547A0 (it) 1981-10-22
IT8149547A1 (it) 1983-04-22
JPS5879950A (ja) 1983-05-13
FR2515175A1 (fr) 1983-04-29
CA1189520A (fr) 1985-06-25
DE3239156A1 (de) 1983-05-05
SE453831B (sv) 1988-03-07
BE894765A (fr) 1983-04-21
US4500731A (en) 1985-02-19
GB2107714B (en) 1985-04-03
SE8205867L (sv) 1983-04-23
FR2515175B1 (fr) 1985-08-23
LU84428A1 (fr) 1983-06-13
ATA388682A (de) 1990-05-15

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Effective date: 19931012