FR2515175B1 - Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant - Google Patents

Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant

Info

Publication number
FR2515175B1
FR2515175B1 FR8217620A FR8217620A FR2515175B1 FR 2515175 B1 FR2515175 B1 FR 2515175B1 FR 8217620 A FR8217620 A FR 8217620A FR 8217620 A FR8217620 A FR 8217620A FR 2515175 B1 FR2515175 B1 FR 2515175B1
Authority
FR
France
Prior art keywords
medicaments
oxo
phenyl
salts
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8217620A
Other languages
English (en)
Other versions
FR2515175A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of FR2515175A1 publication Critical patent/FR2515175A1/fr
Application granted granted Critical
Publication of FR2515175B1 publication Critical patent/FR2515175B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FR8217620A 1981-10-22 1982-10-21 Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant Expired FR2515175B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49547/81A IT1171604B (it) 1981-10-22 1981-10-22 Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione

Publications (2)

Publication Number Publication Date
FR2515175A1 FR2515175A1 (fr) 1983-04-29
FR2515175B1 true FR2515175B1 (fr) 1985-08-23

Family

ID=11270988

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8217620A Expired FR2515175B1 (fr) 1981-10-22 1982-10-21 Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant

Country Status (13)

Country Link
US (1) US4500731A (fr)
JP (1) JPS5879950A (fr)
AT (1) AT391689B (fr)
BE (1) BE894765A (fr)
CA (1) CA1189520A (fr)
CH (1) CH655924A5 (fr)
DE (1) DE3239156A1 (fr)
FR (1) FR2515175B1 (fr)
GB (1) GB2107714B (fr)
IT (1) IT1171604B (fr)
LU (1) LU84428A1 (fr)
NL (1) NL8204062A (fr)
SE (1) SE453831B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454355B (sv) * 1983-01-24 1988-04-25 Roussel Uclaf Akrylsyraderivat innehallande en furyl-, pyranyl-, bensofuranyl-, oxazolyl- eller isoxazolylgrupp, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat
JPH0641440B2 (ja) * 1985-06-05 1994-06-01 鐘淵化学工業株式会社 トランス−β−ベンゾイルアクリル酸エステルの製造法
IL79280A (en) * 1985-07-05 1990-07-12 Smith Kline French Lab 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them
IT1190340B (it) * 1986-06-06 1988-02-16 Roussel Maestretti Spa Derivati dell'acido 4-fenil 4-osso 2-butenoico,loro procedimento di preparazione e loro impiego come prodotti medicinali
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater
US5216024A (en) * 1987-07-28 1993-06-01 Baylor College Of Medicine Cell growth inhibitors and methods of treating cancer and cell proliferative diseases
HU198292B (en) * 1987-09-25 1989-09-28 Richter Gedeon Vegyeszet Process for producing salicilates and pharmaceutical compositions comprising such active ingredient
JPH04235142A (ja) * 1991-01-09 1992-08-24 Kanegafuchi Chem Ind Co Ltd トランス−β−アロイルアクリル酸エステル類の製造法
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent
US7101910B2 (en) * 2001-06-12 2006-09-05 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6717403A (fr) * 1966-12-30 1968-07-01
BE758462A (fr) * 1969-11-04 1971-05-04 Basf Ag Procede pour l'obtention de composes carbonyles beta-hydroxy etalpha-non satures
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
CH591415A5 (en) * 1972-09-13 1977-09-15 Takeda Chemical Industries Ltd 3-(Tri-substd. benzoyl) propionic acids - as relaxants or spasmolytics for the gall bladder
FR2300551A2 (fr) * 1975-02-17 1976-09-10 Fabre Sa Pierre Nouveaux
FR2504005A2 (fr) * 1980-04-24 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide 4-phenyl 4-oxo-2-butenoique
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique

Also Published As

Publication number Publication date
ATA388682A (de) 1990-05-15
SE453831B (sv) 1988-03-07
NL8204062A (nl) 1983-05-16
CH655924A5 (fr) 1986-05-30
CA1189520A (fr) 1985-06-25
AT391689B (de) 1990-11-12
SE8205867L (sv) 1983-04-23
JPS5879950A (ja) 1983-05-13
FR2515175A1 (fr) 1983-04-29
SE8205867D0 (sv) 1982-10-15
IT1171604B (it) 1987-06-10
IT8149547A0 (it) 1981-10-22
GB2107714A (en) 1983-05-05
LU84428A1 (fr) 1983-06-13
US4500731A (en) 1985-02-19
BE894765A (fr) 1983-04-21
GB2107714B (en) 1985-04-03
DE3239156A1 (de) 1983-05-05

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Legal Events

Date Code Title Description
ST Notification of lapse