FR2452495A1 - 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation - Google Patents

2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation

Info

Publication number
FR2452495A1
FR2452495A1 FR8006886A FR8006886A FR2452495A1 FR 2452495 A1 FR2452495 A1 FR 2452495A1 FR 8006886 A FR8006886 A FR 8006886A FR 8006886 A FR8006886 A FR 8006886A FR 2452495 A1 FR2452495 A1 FR 2452495A1
Authority
FR
France
Prior art keywords
alkyl
fortimicins
epi
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8006886A
Other languages
English (en)
Other versions
FR2452495B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2452495A1 publication Critical patent/FR2452495A1/fr
Application granted granted Critical
Publication of FR2452495B1 publication Critical patent/FR2452495B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

2-EPI-FORTIMICINES A ET B ET DERIVES, LEUR PREPARATION ET LEURS UTILISATIONS THERAPEUTIQUES. CES COMPOSES REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE L'HYDROGENE OU UN GROUPE ALKYLE INFERIEUR; R REPRESENTE L'HYDROGENE OU UN GROUPE HYDROXY; R REPRESENTE UN GROUPE METHYLE OU UN ATOME D'HYDROGENE; R EST CHOISI DANS LE GROUPE FORME PAR LES ATOMES D'HYDROGENE, LES GROUPES ALKYLE INFERIEUR, AMINOALKYLE INFERIEUR, DIAMINO-(ALKYLE INFERIEUR), N-(ALKYL INFERIEUR)-AMINOALKYLE, N,N-DI-(ALKYL INFERIEUR)-AMINOALKYLE INFERIEUR, HYDROXYALKYLE INFERIEUR, AMINOHYDROXYALKYLE INFERIEUR, N-(ALKYL INFERIEUR)-AMINOHYDROXYALKYLE INFERIEUR, N,N-DI-(ALKYL INFERIEUR)-AMINOHYDROXYALKYLE
FR8006886A 1979-03-29 1980-03-27 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation Granted FR2452495A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2523679A 1979-03-29 1979-03-29
US06/079,130 US4331804A (en) 1979-03-29 1979-09-26 2-Epi-fortimicin A and derivatives

Publications (2)

Publication Number Publication Date
FR2452495A1 true FR2452495A1 (fr) 1980-10-24
FR2452495B1 FR2452495B1 (fr) 1983-04-08

Family

ID=26699483

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8006886A Granted FR2452495A1 (fr) 1979-03-29 1980-03-27 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation

Country Status (8)

Country Link
US (1) US4331804A (fr)
AU (1) AU5685280A (fr)
CA (1) CA1149814A (fr)
DE (1) DE3012209A1 (fr)
ES (1) ES8107249A1 (fr)
FR (1) FR2452495A1 (fr)
GB (1) GB2051041B (fr)
GR (1) GR67757B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134563A1 (fr) * 1983-08-18 1985-03-20 Kowa Company, Ltd. Dérivés d'amino glycosides et leurs sels d'additions acides et leurs procédés de préparation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418193A (en) * 1982-04-09 1983-11-29 Abbott Laboratories Method of producing 2-epi-fortimicin A

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2375250A1 (fr) * 1976-12-27 1978-07-21 Abbott Lab 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091032A (en) * 1976-09-23 1978-05-23 Abbott Laboratories 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4169198A (en) * 1977-12-21 1979-09-25 Abbott Laboratories 2-Deoxyfortimicin B

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2375250A1 (fr) * 1976-12-27 1978-07-21 Abbott Lab 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134563A1 (fr) * 1983-08-18 1985-03-20 Kowa Company, Ltd. Dérivés d'amino glycosides et leurs sels d'additions acides et leurs procédés de préparation

Also Published As

Publication number Publication date
GB2051041B (en) 1983-11-23
GB2051041A (en) 1981-01-14
ES490011A0 (es) 1981-10-01
GR67757B (fr) 1981-09-22
AU5685280A (en) 1980-10-02
US4331804A (en) 1982-05-25
DE3012209A1 (de) 1980-10-09
ES8107249A1 (es) 1981-10-01
FR2452495B1 (fr) 1983-04-08
CA1149814A (fr) 1983-07-12

Similar Documents

Publication Publication Date Title
DE3066827D1 (en) Piperidine derivatives, their preparation and pharmaceutical compositions containing them
DK202882A (da) Fremgangsmaade til fremstilling af 1-alkyl-2-aminotetralinderivater
ATE1814T1 (de) 9-hydroxyalkylpurine, verfahren zu ihrer herstellung und 9-hydroxyalkylpurine als aktive mittel enthaltende therapeutische zusammensetzung.
JPS5432460A (en) Cycloalkylidenemethylphenylacetic acid derivative and their preparation
RO93855A (fr) Procede pour la preparation des derives d'arylcyclobutylalkylamine
PT69618A (de) Neue imidazolderivate verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praparate
ES8504738A1 (es) Procedimiento para la obtencion de nuevos derivados de mercaptoimidazol
EP0132764A3 (en) New compounds derived from diphenyl-methylene-ethylamine
FR2386544A1 (fr) Procede pour la preparation de derives d'imidazodiazepine
DE3172757D1 (en) Imidazole derivatives, process for their preparation and their pharmaceutical compositions
KR910000711A (ko) 크로만 유도체
FR2456109A1 (fr) Nouveaux derives a substituants heterocycliques de 7-oximinoacetamido-cephalosporines, utiles notamment comme antibiotiques, et leur procede de preparation
KR940003953A (ko) 1. 4-벤조디옥산 유도체
FR2452495A1 (fr) 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation
DK287980A (da) Fremgangsmaade til fremstilling af anthracyclinglycosider
ES8707518A1 (es) Un procedimiento para preparar nuevos derivados del 1,3-ben-zoxatiol
FR2421181A1 (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
FR2369288A1 (fr) Procede de preparation de composes organiques d'etain
FR2424912A1 (fr) Derives de l'imidazole utilisables notamment pour le traitement de l'hypertension
FI843208A (fi) 7 -substituerade 3-oxo-17 -pregn-4-en -21,17-karbolaktoner, foerfaranden foer framstaellning av dem och farmaceutiska preparat innehaollande dem.
FR2455599A1 (fr) Derives de l'acide 2-hydroxy-5- (1-hydroxy-2 (4- (2-oxo-1-benzimidazolinyl)-piperidino)-ethyl) -benzoique, leur preparation et leurs utilisations comme spasmolytiques et anti-hypertenseurs
ES468293A1 (es) Procedimiento para preparar derivados de a-nor-androsta-3 (5),16-dien-2-ona.
FR2452494A1 (fr) 1-epi-fortimicine a et ses derives, utiles notamment comme antibiotiques
DE3175939D1 (en) Use of gamma-piperidino-butyrophenones for the preparation of medicaments for treating diarrhoea
BE902911A (fr) Derives n-imidazolyliques et leur preparation

Legal Events

Date Code Title Description
ST Notification of lapse