ATE177751T1 - Delta 16 ungesättigtes c17 heterocyclische steroide zur verwendung als steroid c17-20 lyase inhibitoren - Google Patents

Delta 16 ungesättigtes c17 heterocyclische steroide zur verwendung als steroid c17-20 lyase inhibitoren

Info

Publication number
ATE177751T1
ATE177751T1 AT94929935T AT94929935T ATE177751T1 AT E177751 T1 ATE177751 T1 AT E177751T1 AT 94929935 T AT94929935 T AT 94929935T AT 94929935 T AT94929935 T AT 94929935T AT E177751 T1 ATE177751 T1 AT E177751T1
Authority
AT
Austria
Prior art keywords
steroid
delta
unsaturated
lyase inhibitors
steroids
Prior art date
Application number
AT94929935T
Other languages
English (en)
Inventor
Norton P Peet
Joseph P Burkhart
Cynthia P Gates
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE177751T1 publication Critical patent/ATE177751T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94929935T 1993-10-27 1994-09-29 Delta 16 ungesättigtes c17 heterocyclische steroide zur verwendung als steroid c17-20 lyase inhibitoren ATE177751T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14367993A 1993-10-27 1993-10-27

Publications (1)

Publication Number Publication Date
ATE177751T1 true ATE177751T1 (de) 1999-04-15

Family

ID=22505119

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929935T ATE177751T1 (de) 1993-10-27 1994-09-29 Delta 16 ungesättigtes c17 heterocyclische steroide zur verwendung als steroid c17-20 lyase inhibitoren

Country Status (19)

Country Link
US (3) US5677293A (de)
EP (1) EP0724591B1 (de)
JP (1) JPH09511214A (de)
KR (1) KR960705838A (de)
CN (1) CN1046736C (de)
AT (1) ATE177751T1 (de)
AU (2) AU684844B2 (de)
CA (1) CA2173729C (de)
DE (1) DE69417248T2 (de)
DK (1) DK0724591T3 (de)
ES (1) ES2133582T3 (de)
FI (1) FI961792A7 (de)
GR (1) GR3030263T3 (de)
HU (1) HUT73855A (de)
IL (1) IL111364A0 (de)
NO (1) NO961693L (de)
NZ (1) NZ274694A (de)
WO (1) WO1995011914A1 (de)
ZA (1) ZA948310B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
WO2001005364A1 (en) * 1999-07-15 2001-01-25 The Procter & Gamble Company Nitrogen-containing steroid compounds and their use to regulate hair growth
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US6562457B1 (en) 2001-10-31 2003-05-13 E. I. Du Pont De Nemours And Company Polyether ester elastomer comprising polytrimethylene ether ester soft segment and tetramethylene ester hard segment
US8569275B2 (en) * 2002-08-28 2013-10-29 Harbor Therapeutics, Inc. Steroids having 7-oxgen and 17-heteroaryl substitution
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
SG175896A1 (en) 2009-05-06 2011-12-29 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20110178065A1 (en) * 2010-01-15 2011-07-21 Biomarin Pharmaceutical Inc. Novel cyp17 inhibitors
CN103124563B (zh) 2010-08-04 2016-08-10 佩尔菲丘尔制药有限公司 用于前列腺癌治疗的联合治疗
CN102746358B (zh) * 2011-04-22 2016-02-10 天津金耀集团有限公司 一种合成孕甾21位溴化物的工艺
CN102898495B (zh) * 2012-11-12 2014-11-26 浙江神洲药业有限公司 醋酸阿比特龙酯的制备方法
CN103059091B (zh) * 2012-11-22 2017-04-19 常州靶点医药科技有限公司 一种避免重金属残留的醋酸阿比特龙的制备方法
US20160022606A1 (en) 2013-03-14 2016-01-28 Pellficure Pharmaceuticals Inc. Novel therapy for prostate carcinoma
EP3191087A1 (de) 2014-09-12 2017-07-19 Pellficure Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur behandlung von prostatakrebs
HUP1500055A1 (hu) 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Abirateron acetát komplexei, eljárás elõállításukra, és az azokat tartalmazó gyógyászati készítmények
WO2018080933A1 (en) 2016-10-24 2018-05-03 Pellficure Pharmaceuticals Inc. Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione
CN106866773A (zh) * 2017-02-14 2017-06-20 西北农林科技大学 一组具有抗癌活性吡唑基甾体衍生物的制备方法及应用
CN116621905B (zh) * 2023-06-06 2025-07-15 西北农林科技大学 双烯噻唑类衍生物及其合成方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1081647A (en) * 1965-04-01 1967-08-31 Shionogi & Co Furan compounds
AT253975B (de) * 1965-06-15 1967-05-10 Carinthia Elektrogeraete Ges M Trockenrasierapparat
US3398138A (en) * 1966-05-24 1968-08-20 American Home Prod Novel cardenolides and derivatives
US3436390A (en) * 1966-05-24 1969-04-01 American Home Prod 4,4-dihydroxy-2-butenoic acid lactones
US4259240A (en) * 1979-09-28 1981-03-31 Advance Biofactures Corporation Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom
US4380624A (en) * 1981-07-31 1983-04-19 Advance Biofactures Corp. Novel isomers of bufalin and resibufogenin and their preparation
US4523917A (en) * 1983-12-27 1985-06-18 Dana Corporation Variable pitch diameter torque sensing pulley assembly
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
ES2138618T3 (es) * 1992-03-31 2000-01-16 Btg Int Ltd Esteroides 17-sustituidos utiles en el tratamiento del cancer.
DE4221636C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate

Also Published As

Publication number Publication date
FI961792A0 (fi) 1996-04-26
US5977094A (en) 1999-11-02
NZ274694A (en) 1998-01-26
CN1046736C (zh) 1999-11-24
AU695341B2 (en) 1998-08-13
WO1995011914A1 (en) 1995-05-04
FI961792L (fi) 1996-04-26
NO961693D0 (no) 1996-04-26
DK0724591T3 (da) 1999-09-27
EP0724591A1 (de) 1996-08-07
CA2173729A1 (en) 1995-05-04
DE69417248T2 (de) 1999-08-19
CN1133596A (zh) 1996-10-16
DE69417248D1 (de) 1999-04-22
AU3993097A (en) 1998-01-08
US5965548A (en) 1999-10-12
HU9601113D0 (en) 1996-07-29
GR3030263T3 (en) 1999-08-31
ZA948310B (en) 1995-06-14
AU684844B2 (en) 1998-01-08
AU7922394A (en) 1995-05-22
US5677293A (en) 1997-10-14
HUT73855A (en) 1996-09-30
JPH09511214A (ja) 1997-11-11
FI961792A7 (fi) 1996-04-26
CA2173729C (en) 2001-05-15
KR960705838A (ko) 1996-11-08
EP0724591B1 (de) 1999-03-17
IL111364A0 (en) 1994-12-29
ES2133582T3 (es) 1999-09-16
NO961693L (no) 1996-04-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee