DK0579939T3 - Phospholipidderivater - Google Patents

Phospholipidderivater

Info

Publication number
DK0579939T3
DK0579939T3 DK93108904T DK93108904T DK0579939T3 DK 0579939 T3 DK0579939 T3 DK 0579939T3 DK 93108904 T DK93108904 T DK 93108904T DK 93108904 T DK93108904 T DK 93108904T DK 0579939 T3 DK0579939 T3 DK 0579939T3
Authority
DK
Denmark
Prior art keywords
phospholipid
medicaments
preparation processes
phospholipid derivatives
processes therefor
Prior art date
Application number
DK93108904T
Other languages
Danish (da)
English (en)
Inventor
Juergen Prof Engel
Wolfgang Dr Schumacher
Gerhard Dr Noessner
Bernhard Dr Kutscher
Peter Dr Hilgard
Jurij Dr Stekar
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Application granted granted Critical
Publication of DK0579939T3 publication Critical patent/DK0579939T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532Seven-(or more) membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK93108904T 1992-07-11 1993-06-03 Phospholipidderivater DK0579939T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (de) 1992-07-11 1992-07-11 Neue Phospholipidderivate

Publications (1)

Publication Number Publication Date
DK0579939T3 true DK0579939T3 (da) 1999-09-20

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93108904T DK0579939T3 (da) 1992-07-11 1993-06-03 Phospholipidderivater

Country Status (31)

Country Link
EP (1) EP0579939B1 (sl)
JP (1) JP3311431B2 (sl)
KR (1) KR100297180B1 (sl)
CN (1) CN1039012C (sl)
AT (1) ATE176477T1 (sl)
AU (1) AU664101B2 (sl)
BR (1) BR9302809A (sl)
CA (2) CA2100228C (sl)
CZ (1) CZ290863B6 (sl)
DE (2) DE4222910A1 (sl)
DK (1) DK0579939T3 (sl)
EE (1) EE03140B1 (sl)
ES (1) ES2129053T3 (sl)
FI (1) FI111262B (sl)
GR (1) GR3029602T3 (sl)
HR (1) HRP931046B1 (sl)
HU (1) HU218783B (sl)
IL (1) IL106289A (sl)
LT (1) LT3113B (sl)
LV (1) LV10870B (sl)
MX (1) MX9304133A (sl)
NO (1) NO306468B1 (sl)
PL (3) PL177811B1 (sl)
RU (1) RU2108336C1 (sl)
SG (1) SG46249A1 (sl)
SI (1) SI9300365B (sl)
SK (1) SK283827B6 (sl)
TW (1) TW304956B (sl)
UA (1) UA40567C2 (sl)
YU (1) YU49079B (sl)
ZA (1) ZA934971B (sl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007008810A (es) 2005-01-21 2007-11-21 Astex Therapeutics Ltd Compuestos farmaceuticos.
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
JP5232009B2 (ja) 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用
EP1869981A1 (de) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3164332D1 (en) * 1980-10-21 1984-07-26 Boehringer Mannheim Gmbh Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
DE3530767A1 (de) * 1985-08-28 1987-03-12 Max Planck Gesellschaft Mittel gegen multiple sklerose
CA1338627C (en) * 1985-12-04 1996-10-01 Hansjorg Eibl Pharmaceuticals based on phosphoric acid esters for use in tumor therapy, and process for their preparation
ES2036210T3 (es) * 1986-07-14 1993-05-16 Nippon Chemiphar Co., Ltd. Un procedimiento para la preparacion de un derivado de glicerol.
US4962096A (en) * 1987-03-24 1990-10-09 Nippon Chemiphar Co., Ltd. Heterocyclic glycerol derivatives and their use as anti-hypertensive agents
DE3906952A1 (de) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
HU218783B (hu) 2000-12-28
LV10870A (lv) 1995-10-20
EP0579939A1 (de) 1994-01-26
AU4186493A (en) 1994-01-13
SI9300365B (sl) 2002-02-28
CN1084175A (zh) 1994-03-23
SK67093A3 (en) 1995-03-08
CN1039012C (zh) 1998-07-08
CA2511753A1 (en) 1994-01-12
DE59309355D1 (de) 1999-03-18
CA2511753C (en) 2007-09-25
SK283827B6 (sk) 2004-02-03
DE4222910A1 (de) 1994-01-13
NO932502L (no) 1994-01-12
UA40567C2 (uk) 2001-08-15
LV10870B (en) 1996-06-20
ZA934971B (en) 1994-02-01
EP0579939B1 (de) 1999-02-03
PL177811B1 (pl) 2000-01-31
FI933165A0 (fi) 1993-07-09
GR3029602T3 (en) 1999-06-30
YU47393A (sh) 1997-08-22
PL173388B1 (pl) 1998-02-27
LTIP620A (en) 1994-07-15
IL106289A0 (en) 1994-04-12
KR940002265A (ko) 1994-02-17
LT3113B (en) 1994-12-27
JPH0733791A (ja) 1995-02-03
CZ124993A3 (en) 1995-03-15
CZ290863B6 (cs) 2002-11-13
YU49079B (sh) 2003-08-29
PL175607B1 (pl) 1999-01-29
MX9304133A (es) 1994-04-29
SI9300365A (en) 1994-03-31
NO932502D0 (no) 1993-07-08
CA2100228A1 (en) 1994-01-12
CA2100228C (en) 2006-01-24
ES2129053T3 (es) 1999-06-01
KR100297180B1 (ko) 2001-11-30
PL299624A1 (en) 1994-02-21
HU9301992D0 (en) 1993-09-28
HRP931046B1 (en) 2000-06-30
IL106289A (en) 2000-06-01
EE03140B1 (et) 1998-12-15
FI111262B (fi) 2003-06-30
BR9302809A (pt) 1994-03-15
SG46249A1 (en) 1998-02-20
HRP931046A2 (en) 1997-04-30
NO306468B1 (no) 1999-11-08
FI933165A (fi) 1994-01-12
RU2108336C1 (ru) 1998-04-10
AU664101B2 (en) 1995-11-02
TW304956B (sl) 1997-05-11
HUT64548A (en) 1994-01-28
ATE176477T1 (de) 1999-02-15
JP3311431B2 (ja) 2002-08-05

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