DE69940115D1 - Heterocyclische inhibitoren von p38 - Google Patents

Heterocyclische inhibitoren von p38

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Publication number
DE69940115D1
DE69940115D1 DE69940115T DE69940115T DE69940115D1 DE 69940115 D1 DE69940115 D1 DE 69940115D1 DE 69940115 T DE69940115 T DE 69940115T DE 69940115 T DE69940115 T DE 69940115T DE 69940115 D1 DE69940115 D1 DE 69940115D1
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Germany
Prior art keywords
heterocyclic inhibitors
heterocyclic
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69940115T
Other languages
English (en)
Inventor
Francesco Salituro
Vincent Galullo
Steven Bellon
Guy Bemis
John Cochran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Vertex Pharmaceuticals Inc
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Publication date
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Publication of DE69940115D1 publication Critical patent/DE69940115D1/de
Anticipated expiration legal-status Critical
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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NO20005673L (no) 2001-01-10
CA2331460A1 (en) 1999-11-18
CN1306512A (zh) 2001-08-01
GEP20032954B (en) 2003-04-25
MY132496A (en) 2007-10-31
AP2000001996A0 (en) 2000-12-31
EP2336111A1 (de) 2011-06-22
HUP0105174A3 (en) 2002-06-28
IL139479A0 (en) 2001-11-25
US20090075981A1 (en) 2009-03-19
EE200000610A (et) 2002-04-15
SK16882000A3 (sk) 2001-05-10
CZ300702B6 (cs) 2009-07-22
KR100696219B1 (ko) 2007-03-21
ATE417828T1 (de) 2009-01-15
US20020019393A1 (en) 2002-02-14
WO1999058502A1 (en) 1999-11-18
PL198352B1 (pl) 2008-06-30
EP1077943B1 (de) 2008-12-17
JP2002514625A (ja) 2002-05-21
KR20010043509A (ko) 2001-05-25
TWI249527B (en) 2006-02-21
US7115637B2 (en) 2006-10-03
NO20005673D0 (no) 2000-11-10
BG105031A (en) 2001-10-31
US6632945B2 (en) 2003-10-14
BR9911786A (pt) 2001-04-03
PT1077943E (pt) 2009-02-23
CZ20004172A3 (cs) 2001-03-14
JP4704560B2 (ja) 2011-06-15
US20040132729A1 (en) 2004-07-08
UA74325C2 (uk) 2005-12-15
DK1077943T3 (da) 2009-03-16
EP2062879A1 (de) 2009-05-27
US7423049B2 (en) 2008-09-09
EA200001176A1 (ru) 2001-06-25
CA2331460C (en) 2011-01-18
HK1034907A1 (en) 2001-11-09
IS5711A (is) 2000-11-10
JP2010150282A (ja) 2010-07-08
NZ508653A (en) 2003-07-25
PL344046A1 (en) 2001-09-24
EP1077943A1 (de) 2001-02-28
AU764047B2 (en) 2003-08-07
US20070060572A1 (en) 2007-03-15
IL139479A (en) 2009-11-18
ES2318893T3 (es) 2009-05-01
AU3792399A (en) 1999-11-29
NO319755B1 (no) 2005-09-12
SK286689B6 (sk) 2009-03-05
HUP0105174A2 (hu) 2002-04-29

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