NO20005673D0 - Heterocykliske inhibitorer av P38 - Google Patents

Heterocykliske inhibitorer av P38

Info

Publication number
NO20005673D0
NO20005673D0 NO20005673A NO20005673A NO20005673D0 NO 20005673 D0 NO20005673 D0 NO 20005673D0 NO 20005673 A NO20005673 A NO 20005673A NO 20005673 A NO20005673 A NO 20005673A NO 20005673 D0 NO20005673 D0 NO 20005673D0
Authority
NO
Norway
Prior art keywords
heterocyclic inhibitors
heterocyclic
inhibitors
Prior art date
Application number
NO20005673A
Other languages
English (en)
Other versions
NO20005673L (no
NO319755B1 (no
Inventor
Francesco Gerald Salituro
Vincent Galullo
Steven Bellon
Guy W Bemis
John E Cochran
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20005673D0 publication Critical patent/NO20005673D0/no
Publication of NO20005673L publication Critical patent/NO20005673L/no
Publication of NO319755B1 publication Critical patent/NO319755B1/no

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/72—Nitrogen atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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BG105031A (en) 2001-10-31
WO1999058502A1 (en) 1999-11-18
PL198352B1 (pl) 2008-06-30
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PL344046A1 (en) 2001-09-24
BR9911786A (pt) 2001-04-03
AP2000001996A0 (en) 2000-12-31
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US20070060572A1 (en) 2007-03-15
IL139479A0 (en) 2001-11-25
US20020019393A1 (en) 2002-02-14
JP2010150282A (ja) 2010-07-08
US6632945B2 (en) 2003-10-14
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CA2331460A1 (en) 1999-11-18
US20090075981A1 (en) 2009-03-19
US7115637B2 (en) 2006-10-03
SK16882000A3 (sk) 2001-05-10
DE69940115D1 (de) 2009-01-29
NO319755B1 (no) 2005-09-12
MY132496A (en) 2007-10-31
JP2002514625A (ja) 2002-05-21
AU764047B2 (en) 2003-08-07
PT1077943E (pt) 2009-02-23
HUP0105174A2 (hu) 2002-04-29
IL139479A (en) 2009-11-18
JP4704560B2 (ja) 2011-06-15
IS5711A (is) 2000-11-10
KR100696219B1 (ko) 2007-03-21
EE200000610A (et) 2002-04-15
KR20010043509A (ko) 2001-05-25
US20040132729A1 (en) 2004-07-08
ATE417828T1 (de) 2009-01-15
CZ300702B6 (cs) 2009-07-22
DK1077943T3 (da) 2009-03-16
EP2062879A1 (en) 2009-05-27
GEP20032954B (en) 2003-04-25
EA200001176A1 (ru) 2001-06-25
CN1306512A (zh) 2001-08-01
SK286689B6 (sk) 2009-03-05
ES2318893T3 (es) 2009-05-01
HK1034907A1 (en) 2001-11-09
CZ20004172A3 (cs) 2001-03-14
US7423049B2 (en) 2008-09-09
EP2336111A1 (en) 2011-06-22
HUP0105174A3 (en) 2002-06-28
UA74325C2 (uk) 2005-12-15
CA2331460C (en) 2011-01-18
EP1077943A1 (en) 2001-02-28
AU3792399A (en) 1999-11-29

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