DE69823931D1 - Chromatographieverfahren für Reinigung von IgG mit hoher Ausbeute und Virusinaktivierung - Google Patents
Chromatographieverfahren für Reinigung von IgG mit hoher Ausbeute und VirusinaktivierungInfo
- Publication number
- DE69823931D1 DE69823931D1 DE69823931T DE69823931T DE69823931D1 DE 69823931 D1 DE69823931 D1 DE 69823931D1 DE 69823931 T DE69823931 T DE 69823931T DE 69823931 T DE69823931 T DE 69823931T DE 69823931 D1 DE69823931 D1 DE 69823931D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- caprylate
- purification
- solution
- precipitate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/23—Solid substances, e.g. granules, powders, blocks, tablets
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/22—Blood or products thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/879,362 US5886154A (en) | 1997-06-20 | 1997-06-20 | Chromatographic method for high yield purification and viral inactivation of antibodies |
US879362 | 1997-06-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69823931D1 true DE69823931D1 (de) | 2004-06-24 |
DE69823931T2 DE69823931T2 (de) | 2005-06-16 |
Family
ID=25374006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69823931T Expired - Lifetime DE69823931T2 (de) | 1997-06-20 | 1998-06-09 | Chromatographieverfahren für Reinigung von IgG mit hoher Ausbeute und Virusinaktivierung |
Country Status (10)
Country | Link |
---|---|
US (5) | US5886154A (de) |
EP (1) | EP0893450B1 (de) |
JP (1) | JP4359347B2 (de) |
AT (1) | ATE267214T1 (de) |
AU (1) | AU749336B2 (de) |
CA (2) | CA2239237C (de) |
DE (1) | DE69823931T2 (de) |
DK (1) | DK0893450T3 (de) |
ES (1) | ES2221096T3 (de) |
PT (1) | PT893450E (de) |
Families Citing this family (103)
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JP4685238B2 (ja) * | 1998-06-09 | 2011-05-18 | ツエー・エス・エル・ベーリング・アクチエンゲゼルシヤフト | 静脈投与用免疫グロブリン及び他の免疫グロブリン生成物の製造法 |
JP3096737B1 (ja) * | 1999-07-19 | 2000-10-10 | 工業技術院長 | ヒト・動物細胞培養液 |
SE0001128D0 (sv) * | 2000-03-30 | 2000-03-30 | Amersham Pharm Biotech Ab | A method of producing IgG |
WO2002072615A1 (fr) * | 2001-03-09 | 2002-09-19 | Chugai Seiyaku Kabushiki Kaisha | Methode de purification de proteines |
US6893639B2 (en) * | 2001-10-19 | 2005-05-17 | Hemacare Corporation | Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates |
US20040022792A1 (en) * | 2002-06-17 | 2004-02-05 | Ralph Klinke | Method of stabilizing proteins at low pH |
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SI1561756T1 (sl) | 2002-09-11 | 2016-02-29 | Chugai Seiyaku Kabushiki Kaisha | Postopek čiščenja proteinov |
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FR2899111B1 (fr) * | 2006-03-31 | 2010-09-03 | Lab Francais Du Fractionnement | Concentre d'immunoglobulines specifiques du chikungunya en tant que medicament. |
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-
1997
- 1997-06-20 US US08/879,362 patent/US5886154A/en not_active Expired - Lifetime
-
1998
- 1998-04-02 JP JP10535298A patent/JP4359347B2/ja not_active Expired - Lifetime
- 1998-05-29 CA CA002239237A patent/CA2239237C/en not_active Expired - Lifetime
- 1998-05-29 CA CA2676074A patent/CA2676074C/en not_active Expired - Lifetime
- 1998-06-09 DK DK98110526T patent/DK0893450T3/da active
- 1998-06-09 PT PT98110526T patent/PT893450E/pt unknown
- 1998-06-09 EP EP98110526A patent/EP0893450B1/de not_active Expired - Lifetime
- 1998-06-09 AT AT98110526T patent/ATE267214T1/de active
- 1998-06-09 ES ES98110526T patent/ES2221096T3/es not_active Expired - Lifetime
- 1998-06-09 DE DE69823931T patent/DE69823931T2/de not_active Expired - Lifetime
- 1998-06-10 AU AU70099/98A patent/AU749336B2/en not_active Expired
-
1999
- 1999-03-17 US US09/270,724 patent/US6307028B1/en not_active Expired - Lifetime
-
2001
- 2001-10-09 US US09/973,141 patent/US20020177693A1/en not_active Abandoned
-
2007
- 2007-10-17 US US11/873,878 patent/USRE43655E1/en not_active Expired - Lifetime
-
2012
- 2012-07-19 US US13/553,364 patent/USRE44558E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH1129494A (ja) | 1999-02-02 |
CA2239237A1 (en) | 1998-12-20 |
DK0893450T3 (da) | 2004-09-13 |
CA2676074A1 (en) | 1998-12-20 |
USRE43655E1 (en) | 2012-09-11 |
CA2676074C (en) | 2015-10-06 |
ATE267214T1 (de) | 2004-06-15 |
ES2221096T3 (es) | 2004-12-16 |
US20020177693A1 (en) | 2002-11-28 |
USRE44558E1 (en) | 2013-10-22 |
EP0893450A1 (de) | 1999-01-27 |
AU7009998A (en) | 1998-12-24 |
PT893450E (pt) | 2004-09-30 |
US6307028B1 (en) | 2001-10-23 |
AU749336B2 (en) | 2002-06-27 |
CA2239237C (en) | 2010-02-02 |
DE69823931T2 (de) | 2005-06-16 |
US5886154A (en) | 1999-03-23 |
JP4359347B2 (ja) | 2009-11-04 |
EP0893450B1 (de) | 2004-05-19 |
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