DK450785D0 - Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed - Google Patents

Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed

Info

Publication number
DK450785D0
DK450785D0 DK450785A DK450785A DK450785D0 DK 450785 D0 DK450785 D0 DK 450785D0 DK 450785 A DK450785 A DK 450785A DK 450785 A DK450785 A DK 450785A DK 450785 D0 DK450785 D0 DK 450785D0
Authority
DK
Denmark
Prior art keywords
weight
solution
polyethylene glycol
high purity
combination
Prior art date
Application number
DK450785A
Other languages
English (en)
Other versions
DK163107B (da
DK450785A (da
Inventor
Gautam Mitra
Paul K Ng
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of DK450785D0 publication Critical patent/DK450785D0/da
Publication of DK450785A publication Critical patent/DK450785A/da
Publication of DK163107B publication Critical patent/DK163107B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
DK450785A 1984-10-04 1985-10-03 Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed DK163107B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/658,081 US4543210A (en) 1984-10-04 1984-10-04 Process for producing a high purity antihemophilic factor concentrate
US65808184 1984-10-04

Publications (3)

Publication Number Publication Date
DK450785D0 true DK450785D0 (da) 1985-10-03
DK450785A DK450785A (da) 1986-04-05
DK163107B DK163107B (da) 1992-01-20

Family

ID=24639818

Family Applications (1)

Application Number Title Priority Date Filing Date
DK450785A DK163107B (da) 1984-10-04 1985-10-03 Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed

Country Status (7)

Country Link
US (1) US4543210A (da)
EP (1) EP0176926B1 (da)
JP (1) JPH0676337B2 (da)
AT (1) ATE44236T1 (da)
CA (1) CA1243950A (da)
DE (1) DE3571201D1 (da)
DK (1) DK163107B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984003628A1 (en) * 1983-05-09 1984-09-27 Nordisk Insulinlab A concentrate of the antihemophilic factor viii and a process for producing it
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
AU6487286A (en) * 1985-11-08 1987-05-14 Baxter Travenol Laboratories Inc. Antihemophilic factor by cold precipitation
EP0238701B1 (de) * 1986-03-27 1992-03-18 Octapharma AG Verfahren zur Herstellung eines hochgereinigten Antihämophilie-Faktors
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
EP0321835B1 (en) * 1987-12-21 1994-09-28 Miles Inc. Gel filteration of factor VIII
US5177191A (en) * 1987-12-21 1993-01-05 Miles, Inc. Gel filtration of factor VIII
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
DE3904354A1 (de) * 1989-02-14 1990-08-16 Behringwerke Ag Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.
USH1509H (en) * 1989-06-09 1995-12-05 Eran; Harutyun Heparin enhanced process for separating antihemophilic factor (Factor VIII) and fibronectin from cryoprecipitate
FR2651437A1 (fr) * 1989-09-05 1991-03-08 Lille Transfusion Sanguine Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.
DK162233C (da) * 1989-11-09 1992-03-16 Novo Nordisk As Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
IT1248723B (it) * 1990-06-12 1995-01-26 Scalvo S P A Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo
FR2664165B1 (fr) * 1990-07-03 1992-10-16 Lille Transfusion Sanguine Composition pour stabiliser le plasma sanguin en cours de pasteurisation.
US5525519A (en) * 1992-01-07 1996-06-11 Middlesex Sciences, Inc. Method for isolating biomolecules from a biological sample with linear polymers
DE4202667C1 (da) * 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物
JP5080713B2 (ja) * 1999-12-20 2012-11-21 田辺三菱製薬株式会社 多孔性膜処理によるウイルスの除去された血漿蛋白組成物の製造方法、ウイルスの除去された血漿蛋白組成物およびウイルス除去方法
CA2742328C (en) 2008-11-07 2019-02-26 Baxter International Inc. Factor viii formulations

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29698A (en) * 1860-08-21 Improvement in harvesters
NL286954A (da) * 1962-01-03
US3652530A (en) * 1967-08-28 1972-03-28 American Nat Red Cross Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3631018A (en) * 1970-05-01 1971-12-28 Baxter Laboratories Inc Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate
US3682881A (en) * 1970-10-02 1972-08-08 Baxter Laboratories Inc Fractionation of plasma using glycine and polyethylene glycol
US3803115A (en) * 1972-05-17 1974-04-09 Baxter Laboratories Inc Stabilization of ahf using heparin
US4188318A (en) * 1975-06-16 1980-02-12 Edward Shanbrom Simplified method for preparation of high yield, high purity Factor VIII concentrate
US4069216A (en) * 1975-06-16 1978-01-17 Edward Shanbrom, Inc. Simplified methods for preparation of very high purity Factor VIII concentrate
US4104266A (en) * 1977-04-14 1978-08-01 American National Red Cross Method for preparation of antihemophilic factor
CA1074698A (en) * 1977-12-19 1980-04-01 Gail A. Rock Method of collecting anti-hemophilic factor viii from blood and blood plasma
US4170639A (en) * 1978-07-10 1979-10-09 Warner-Lambert Company Antihemophilic factor concentrate and its production
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma
FR2460305A2 (fr) * 1979-06-29 1981-01-23 Merieux Inst Procede de preparation d'un concentre de facteur viii
SE448945B (sv) * 1979-12-20 1987-03-30 Blombaeck E G B Forfarande for rening och /eller koncentrering av faktor viii-komplexet
US4289691A (en) * 1980-01-18 1981-09-15 The Canadian Red Cross Society Method of obtaining intermediate purity factor VIII
US4386068A (en) * 1980-02-26 1983-05-31 Cutter Laboratories, Inc. Antihemophilic factor concentrate and method for preparation
US4294826A (en) * 1980-05-07 1981-10-13 Armour Pharmaceutical Company Process for the preparation of highly purified antihemophilic factor
AT369263B (de) * 1980-08-27 1982-12-27 Immuno Ag Verfahren zur herstellung eines faktor viii(ahf) -hochkonzentrates
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
US4435318A (en) * 1981-05-22 1984-03-06 Ionics, Incorporated Electrodialysis preparation of purified AHF concentrate
CA1178887A (en) * 1981-10-01 1984-12-04 Gail A. Rock Factor viii concentrates prepared from heparinized plasma by the application of a cold precipitation technique
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4486410A (en) * 1984-02-09 1984-12-04 Armour Pharmaceutical Company Heat defibrinogenation of AHF preparation

Also Published As

Publication number Publication date
EP0176926B1 (en) 1989-06-28
EP0176926A3 (en) 1987-10-28
DE3571201D1 (en) 1989-08-03
ATE44236T1 (de) 1989-07-15
CA1243950A (en) 1988-11-01
JPS6187626A (ja) 1986-05-06
US4543210A (en) 1985-09-24
EP0176926A2 (en) 1986-04-09
JPH0676337B2 (ja) 1994-09-28
DK163107B (da) 1992-01-20
DK450785A (da) 1986-04-05

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