DE69128971D1 - Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte - Google Patents

Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte

Info

Publication number
DE69128971D1
DE69128971D1 DE69128971T DE69128971T DE69128971D1 DE 69128971 D1 DE69128971 D1 DE 69128971D1 DE 69128971 T DE69128971 T DE 69128971T DE 69128971 T DE69128971 T DE 69128971T DE 69128971 D1 DE69128971 D1 DE 69128971D1
Authority
DE
Germany
Prior art keywords
aryl
protecting
taxane
intermediates
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69128971T
Other languages
English (en)
Other versions
DE69128971T2 (de
Inventor
Jean-Dominique Bourzat
Alain Commercon
Jean-Marc Paris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR909014635A external-priority patent/FR2669631B1/fr
Priority claimed from FR9109423A external-priority patent/FR2679557B1/fr
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of DE69128971D1 publication Critical patent/DE69128971D1/de
Publication of DE69128971T2 publication Critical patent/DE69128971T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
DE69128971T 1990-11-23 1991-11-22 Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte Expired - Lifetime DE69128971T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR909014635A FR2669631B1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.
FR9109423A FR2679557B1 (fr) 1991-07-25 1991-07-25 Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69128971D1 true DE69128971D1 (de) 1998-04-02
DE69128971T2 DE69128971T2 (de) 1998-09-24

Family

ID=26228347

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69104223T Expired - Lifetime DE69104223T2 (de) 1990-11-23 1991-11-22 Verfahren zur herstellung von taxanderivaten, so erhaltene neue derivate und pharmazeutische zusammensetzungen, die sie enthalten.
DE69128971T Expired - Lifetime DE69128971T2 (de) 1990-11-23 1991-11-22 Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69104223T Expired - Lifetime DE69104223T2 (de) 1990-11-23 1991-11-22 Verfahren zur herstellung von taxanderivaten, so erhaltene neue derivate und pharmazeutische zusammensetzungen, die sie enthalten.

Country Status (24)

Country Link
US (1) US5476954A (de)
EP (2) EP0595370B1 (de)
JP (1) JP3043411B2 (de)
KR (1) KR100206457B1 (de)
AT (2) ATE111905T1 (de)
AU (1) AU655618B2 (de)
CA (1) CA2096833C (de)
CZ (1) CZ286749B6 (de)
DE (2) DE69104223T2 (de)
DK (2) DK0595370T3 (de)
ES (2) ES2059207T3 (de)
FI (2) FI105184B (de)
GR (1) GR3026238T3 (de)
HU (1) HU214332B (de)
IE (2) IE80681B1 (de)
MX (1) MX9102128A (de)
NO (1) NO302699B1 (de)
NZ (2) NZ240698A (de)
PL (1) PL166893B1 (de)
PT (2) PT99580B (de)
RU (1) RU2095356C1 (de)
SK (1) SK282162B6 (de)
WO (1) WO1992009589A1 (de)
YU (1) YU48150B (de)

Families Citing this family (145)

* Cited by examiner, † Cited by third party
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PT99580B (pt) 1999-07-30
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HU9301500D0 (en) 1993-09-28
EP0558623A1 (de) 1993-09-08
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CA2096833C (fr) 2003-04-08
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MX9102128A (es) 1992-07-08
PT99580A (pt) 1992-10-30
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FI981590A0 (fi) 1991-11-22
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