DE69032083T2 - Carbamoylderivate - Google Patents

Carbamoylderivate

Info

Publication number
DE69032083T2
DE69032083T2 DE69032083T DE69032083T DE69032083T2 DE 69032083 T2 DE69032083 T2 DE 69032083T2 DE 69032083 T DE69032083 T DE 69032083T DE 69032083 T DE69032083 T DE 69032083T DE 69032083 T2 DE69032083 T2 DE 69032083T2
Authority
DE
Germany
Prior art keywords
methyl
acid
ylmethyl
formula
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69032083T
Other languages
German (de)
English (en)
Other versions
DE69032083D1 (de
Inventor
Robert Toms Jacobs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca UK Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of DE69032083D1 publication Critical patent/DE69032083D1/de
Application granted granted Critical
Publication of DE69032083T2 publication Critical patent/DE69032083T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69032083T 1989-12-11 1990-12-10 Carbamoylderivate Expired - Lifetime DE69032083T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898927981A GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative

Publications (2)

Publication Number Publication Date
DE69032083D1 DE69032083D1 (de) 1998-04-09
DE69032083T2 true DE69032083T2 (de) 1998-07-16

Family

ID=10667774

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69032083T Expired - Lifetime DE69032083T2 (de) 1989-12-11 1990-12-10 Carbamoylderivate

Country Status (31)

Country Link
EP (1) EP0432984B1 (enExample)
JP (1) JPH0822849B2 (enExample)
KR (1) KR100192999B1 (enExample)
CN (1) CN1025786C (enExample)
AP (1) AP192A (enExample)
AT (1) ATE163641T1 (enExample)
AU (1) AU642182B2 (enExample)
BG (2) BG50606A3 (enExample)
CA (1) CA2031897C (enExample)
CZ (1) CZ282068B6 (enExample)
DE (1) DE69032083T2 (enExample)
DK (1) DK0432984T3 (enExample)
ES (1) ES2112832T3 (enExample)
FI (1) FI95029C (enExample)
GB (2) GB8927981D0 (enExample)
GR (1) GR3026279T3 (enExample)
HR (1) HRP930326B1 (enExample)
HU (2) HU210441B (enExample)
IE (1) IE904448A1 (enExample)
IL (1) IL96621A (enExample)
MY (1) MY106363A (enExample)
NO (1) NO174198C (enExample)
PL (2) PL166516B1 (enExample)
PT (1) PT96154B (enExample)
RO (1) RO108562B1 (enExample)
RU (1) RU2002740C1 (enExample)
SI (1) SI9012330A (enExample)
SK (1) SK614690A3 (enExample)
TW (1) TW219329B (enExample)
YU (1) YU48218B (enExample)
ZA (1) ZA909898B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113581T1 (de) * 1990-05-04 1994-11-15 Ciba Geigy Ag Substituierte indole.
GB9020338D0 (en) * 1990-09-18 1990-10-31 Lilly Industries Ltd Pharmaceutical compounds
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
ES2050611B1 (es) * 1992-10-08 1994-12-16 Ici Plc Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
WO1996008496A1 (en) * 1994-09-16 1996-03-21 Takeda Chemical Industries, Ltd. Triazolopyridazines process and intermediates for their preparation and their use as medicaments
US7166638B2 (en) * 2003-05-27 2007-01-23 Nicox S.A. Statin derivatives
CN101142184A (zh) * 2004-10-12 2008-03-12 解码遗传Ehf公司 用于阻塞性动脉疾病的磺酰胺迫位取代的双环化合物
KR101377790B1 (ko) * 2005-02-25 2014-03-27 오노 야꾸힝 고교 가부시키가이샤 인돌 화합물 및 이의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524152A (en) * 1982-12-30 1985-06-18 Pennwalt Corporation 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure
EP0227241B1 (en) * 1985-10-17 1996-09-11 Zeneca Inc. Medicinal indole and indazole keto sulphone derivatives
GB8623429D0 (en) * 1985-10-17 1986-11-05 Ici America Inc Carboximide derivatives
MY103259A (en) * 1987-04-15 1993-05-29 Ici America Inc Aliphatic carboxamides
GB8906032D0 (en) * 1988-04-14 1989-04-26 Ici America Inc Hetera-aliphatic carboxamides
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process

Also Published As

Publication number Publication date
KR100192999B1 (ko) 1999-06-15
HK1003830A1 (en) 1998-11-06
FI906084L (fi) 1991-06-12
CA2031897C (en) 2001-12-18
NO905327L (no) 1991-06-12
SK278528B6 (en) 1997-08-06
AP9000230A0 (en) 1991-01-31
IE904448A1 (en) 1991-06-19
EP0432984A2 (en) 1991-06-19
CZ614690A3 (en) 1997-05-14
ES2112832T3 (es) 1998-04-16
IL96621A (en) 1994-11-28
CZ282068B6 (cs) 1997-05-14
HRP930326B1 (en) 1998-12-31
AP192A (en) 1992-06-30
SI9012330A (en) 1997-12-31
CA2031897A1 (en) 1991-06-12
HU210877A9 (en) 1995-09-28
PL167449B1 (pl) 1995-09-30
PL288184A1 (en) 1992-04-21
PL166516B1 (pl) 1995-05-31
KR910011780A (ko) 1991-08-07
NO905327D0 (no) 1990-12-10
MY106363A (en) 1995-05-30
JPH0770061A (ja) 1995-03-14
SK614690A3 (en) 1997-08-06
NO174198B (no) 1993-12-20
BG60015B2 (bg) 1993-06-30
ZA909898B (en) 1991-08-28
HU908137D0 (en) 1991-06-28
GB8927981D0 (en) 1990-02-14
RO108562B1 (ro) 1994-06-30
DK0432984T3 (da) 1998-11-30
AU642182B2 (en) 1993-10-14
PT96154A (pt) 1991-09-30
EP0432984B1 (en) 1998-03-04
IL96621A0 (en) 1991-09-16
NO174198C (no) 1994-04-06
PT96154B (pt) 1998-05-29
RU2002740C1 (ru) 1993-11-15
GB2238790B (en) 1993-06-30
CN1053604A (zh) 1991-08-07
CN1025786C (zh) 1994-08-31
DE69032083D1 (de) 1998-04-09
JPH0822849B2 (ja) 1996-03-06
BG50606A3 (bg) 1992-09-15
HRP930326A2 (en) 1996-06-30
YU48218B (sh) 1997-08-22
FI95029C (fi) 1995-12-11
HUT56345A (en) 1991-08-28
ATE163641T1 (de) 1998-03-15
FI95029B (fi) 1995-08-31
HU210441B (en) 1995-04-28
AU6791790A (en) 1991-06-13
GR3026279T3 (en) 1998-06-30
YU233090A (sh) 1993-05-28
GB2238790A (en) 1991-06-12
FI906084A0 (fi) 1990-12-11
GB9026797D0 (en) 1991-01-30
EP0432984A3 (en) 1992-04-22
TW219329B (enExample) 1994-01-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTRAZENECA UK LTD., LONDON, GB