CN1025786C - 氨基甲酰基衍生物的制备方法 - Google Patents
氨基甲酰基衍生物的制备方法 Download PDFInfo
- Publication number
- CN1025786C CN1025786C CN90110406A CN90110406A CN1025786C CN 1025786 C CN1025786 C CN 1025786C CN 90110406 A CN90110406 A CN 90110406A CN 90110406 A CN90110406 A CN 90110406A CN 1025786 C CN1025786 C CN 1025786C
- Authority
- CN
- China
- Prior art keywords
- methyl
- formula
- acid
- compound
- trifluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
Abstract
Description
Claims (1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898927981A GB8927981D0 (en) | 1989-12-11 | 1989-12-11 | Carbamoyl derivative |
GB8927981.4 | 1989-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1053604A CN1053604A (zh) | 1991-08-07 |
CN1025786C true CN1025786C (zh) | 1994-08-31 |
Family
ID=10667774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN90110406A Expired - Lifetime CN1025786C (zh) | 1989-12-11 | 1990-12-11 | 氨基甲酰基衍生物的制备方法 |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP0432984B1 (zh) |
JP (1) | JPH0822849B2 (zh) |
KR (1) | KR100192999B1 (zh) |
CN (1) | CN1025786C (zh) |
AP (1) | AP192A (zh) |
AT (1) | ATE163641T1 (zh) |
AU (1) | AU642182B2 (zh) |
BG (2) | BG60015A3 (zh) |
CA (1) | CA2031897C (zh) |
CZ (1) | CZ282068B6 (zh) |
DE (1) | DE69032083T2 (zh) |
DK (1) | DK0432984T3 (zh) |
ES (1) | ES2112832T3 (zh) |
FI (1) | FI95029C (zh) |
GB (2) | GB8927981D0 (zh) |
GR (1) | GR3026279T3 (zh) |
HK (1) | HK1003830A1 (zh) |
HR (1) | HRP930326B1 (zh) |
HU (2) | HU210441B (zh) |
IE (1) | IE904448A1 (zh) |
IL (1) | IL96621A (zh) |
MY (1) | MY106363A (zh) |
NO (1) | NO174198C (zh) |
PL (2) | PL167449B1 (zh) |
PT (1) | PT96154B (zh) |
RO (1) | RO108562B1 (zh) |
RU (1) | RU2002740C1 (zh) |
SI (1) | SI9012330A (zh) |
SK (1) | SK614690A3 (zh) |
TW (1) | TW219329B (zh) |
YU (1) | YU48218B (zh) |
ZA (1) | ZA909898B (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE113581T1 (de) * | 1990-05-04 | 1994-11-15 | Ciba Geigy Ag | Substituierte indole. |
GB9020338D0 (en) * | 1990-09-18 | 1990-10-31 | Lilly Industries Ltd | Pharmaceutical compounds |
GB9026427D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Chemical process |
GB9026425D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Process |
GB9119001D0 (en) * | 1991-09-05 | 1991-10-23 | Ici Plc | Pharmaceutical agents |
ES2050611B1 (es) * | 1992-10-08 | 1994-12-16 | Ici Plc | Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos. |
GR1001368B (el) * | 1992-10-08 | 1993-10-29 | Ici Plc | Φαρμακευτικοί φορείς. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4524152A (en) * | 1982-12-30 | 1985-06-18 | Pennwalt Corporation | 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure |
GB8623429D0 (en) * | 1985-10-17 | 1986-11-05 | Ici America Inc | Carboximide derivatives |
EP0227241B1 (en) * | 1985-10-17 | 1996-09-11 | Zeneca Inc. | Medicinal indole and indazole keto sulphone derivatives |
MY103259A (en) * | 1987-04-15 | 1993-05-29 | Ici America Inc | Aliphatic carboxamides |
GB8906032D0 (en) * | 1988-04-14 | 1989-04-26 | Ici America Inc | Hetera-aliphatic carboxamides |
GB9026425D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Process |
-
1989
- 1989-12-11 GB GB898927981A patent/GB8927981D0/en active Pending
-
1990
- 1990-12-10 AP APAP/P/1990/000230A patent/AP192A/en active
- 1990-12-10 IE IE444890A patent/IE904448A1/en not_active IP Right Cessation
- 1990-12-10 ES ES90313373T patent/ES2112832T3/es not_active Expired - Lifetime
- 1990-12-10 ZA ZA909898A patent/ZA909898B/xx unknown
- 1990-12-10 PL PL90304868A patent/PL167449B1/pl unknown
- 1990-12-10 NO NO905327A patent/NO174198C/no unknown
- 1990-12-10 HU HU908137A patent/HU210441B/hu not_active IP Right Cessation
- 1990-12-10 DK DK90313373T patent/DK0432984T3/da active
- 1990-12-10 BG BG93426A patent/BG60015A3/xx unknown
- 1990-12-10 DE DE69032083T patent/DE69032083T2/de not_active Expired - Lifetime
- 1990-12-10 BG BG95502/91A patent/BG50606A3/xx unknown
- 1990-12-10 RO RO146517A patent/RO108562B1/ro unknown
- 1990-12-10 CA CA002031897A patent/CA2031897C/en not_active Expired - Fee Related
- 1990-12-10 IL IL9662190A patent/IL96621A/en not_active IP Right Cessation
- 1990-12-10 SI SI9012330A patent/SI9012330A/sl unknown
- 1990-12-10 AT AT90313373T patent/ATE163641T1/de not_active IP Right Cessation
- 1990-12-10 CZ CS906146A patent/CZ282068B6/cs not_active IP Right Cessation
- 1990-12-10 SK SK6146-90A patent/SK614690A3/sk unknown
- 1990-12-10 PL PL90288184A patent/PL166516B1/pl unknown
- 1990-12-10 MY MYPI90002157A patent/MY106363A/en unknown
- 1990-12-10 GB GB9026797A patent/GB2238790B/en not_active Revoked
- 1990-12-10 YU YU233090A patent/YU48218B/sh unknown
- 1990-12-10 RU SU04831920A patent/RU2002740C1/ru not_active IP Right Cessation
- 1990-12-10 AU AU67917/90A patent/AU642182B2/en not_active Ceased
- 1990-12-10 EP EP90313373A patent/EP0432984B1/en not_active Expired - Lifetime
- 1990-12-11 FI FI906084A patent/FI95029C/fi not_active IP Right Cessation
- 1990-12-11 KR KR1019900020547A patent/KR100192999B1/ko not_active IP Right Cessation
- 1990-12-11 PT PT96154A patent/PT96154B/pt not_active IP Right Cessation
- 1990-12-11 JP JP2419290A patent/JPH0822849B2/ja not_active Expired - Lifetime
- 1990-12-11 CN CN90110406A patent/CN1025786C/zh not_active Expired - Lifetime
- 1990-12-20 TW TW079110705A patent/TW219329B/zh not_active IP Right Cessation
-
1993
- 1993-03-11 HR HRP-2330/90A patent/HRP930326B1/xx not_active IP Right Cessation
-
1995
- 1995-06-12 HU HU95P/P00183P patent/HU210877A9/hu unknown
-
1998
- 1998-03-05 GR GR980400270T patent/GR3026279T3/el unknown
- 1998-04-02 HK HK98102807A patent/HK1003830A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: ZENECA Ltd. Applicant before: Imperial Chemical Industries PLC |
|
CB04 | Change of attorney information |
Agency after: Patent and Trademark Office of China Council For The Promotion Of International Trade Agency before: China Patent Agent (H.K.) Ltd. |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: IMPERIAL CHEMICAL CORPORATION TO: ZENECA CO., LTD.; AGENCY; FROM: CHINA PATENT AGENT(XIANG GANG)LTD. TO: CCPIT PATENT + TRADEMARK LAW OFFICE |
|
C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: ZENECA Ltd. Applicant before: Imperial Chemical Industries PLC |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: IMPERIAL CHEMICAL CORPORATION TO: ZENECA LTD |
|
CI01 | Publication of corrected invention patent application |
Correction item: Patentee Correct: Zeneca Limited False: Zeneca Limited Number: 36 Page: 132 Volume: 10 |
|
ERR | Gazette correction |
Free format text: CORRECT: PATENTEE; FROM: ZENECA CO., LTD. TO: ZENECA LTD |
|
C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
OR01 | Other related matters | ||
ASS | Succession or assignment of patent right |
Owner name: ASTRAZENECA (UK) LIMITED Free format text: FORMER OWNER: SIGENTIS CO., LTD. Effective date: 20061229 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C56 | Change in the name or address of the patentee |
Owner name: SIGENTIS CO., LTD. Free format text: FORMER NAME OR ADDRESS: ZENECA LTD |
|
CP03 | Change of name, title or address |
Address after: surrey Patentee after: SYNGENTA LTD. Address before: England Patentee before: ZENECA Ltd. |
|
TR01 | Transfer of patent right |
Effective date of registration: 20061229 Address after: London, England Patentee after: ASTRAZENECA UK LTD. Address before: surrey Patentee before: SYNGENTA LTD. |
|
C17 | Cessation of patent right | ||
CX01 | Expiry of patent term |
Expiration termination date: 20101211 Granted publication date: 19940831 |