GB8927981D0 - Carbamoyl derivative - Google Patents

Carbamoyl derivative

Info

Publication number
GB8927981D0
GB8927981D0 GB898927981A GB8927981A GB8927981D0 GB 8927981 D0 GB8927981 D0 GB 8927981D0 GB 898927981 A GB898927981 A GB 898927981A GB 8927981 A GB8927981 A GB 8927981A GB 8927981 D0 GB8927981 D0 GB 8927981D0
Authority
GB
United Kingdom
Prior art keywords
carbamoyl derivative
carbamoyl
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB898927981A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB898927981A priority Critical patent/GB8927981D0/en
Publication of GB8927981D0 publication Critical patent/GB8927981D0/en
Priority to BG095502A priority patent/BG50606A3/xx
Priority to CS906146A priority patent/CZ282068B6/cs
Priority to SI9012330A priority patent/SI9012330A/sl
Priority to GB9026797A priority patent/GB2238790B/en
Priority to AT90313373T priority patent/ATE163641T1/de
Priority to ZA909898A priority patent/ZA909898B/xx
Priority to YU233090A priority patent/YU48218B/sh
Priority to HU908137A priority patent/HU210441B/hu
Priority to APAP/P/1990/000230A priority patent/AP192A/en
Priority to AU67917/90A priority patent/AU642182B2/en
Priority to SK6146-90A priority patent/SK614690A3/sk
Priority to IE444890A priority patent/IE904448A1/en
Priority to EP90313373A priority patent/EP0432984B1/en
Priority to MYPI90002157A priority patent/MY106363A/en
Priority to CA002031897A priority patent/CA2031897C/en
Priority to SU04831920A priority patent/RU2002740C1/ru
Priority to DK90313373T priority patent/DK0432984T3/da
Priority to PL90304868A priority patent/PL167449B1/pl
Priority to BG093426A priority patent/BG60015B2/bg
Priority to NO905327A priority patent/NO174198C/no
Priority to PL90288184A priority patent/PL166516B1/pl
Priority to RO146517A priority patent/RO108562B1/ro
Priority to ES90313373T priority patent/ES2112832T3/es
Priority to IL9662190A priority patent/IL96621A/en
Priority to DE69032083T priority patent/DE69032083T2/de
Priority to PT96154A priority patent/PT96154B/pt
Priority to BR909006302A priority patent/BR9006302A/pt
Priority to CN90110406A priority patent/CN1025786C/zh
Priority to KR1019900020547A priority patent/KR100192999B1/ko
Priority to JP2419290A priority patent/JPH0822849B2/ja
Priority to FI906084A priority patent/FI95029C/fi
Priority to TW079110705A priority patent/TW219329B/zh
Priority to US07/927,762 priority patent/US5286740A/en
Priority to HRP-2330/90A priority patent/HRP930326B1/xx
Priority to US08/137,245 priority patent/US5334765A/en
Priority to HU95P/P00183P priority patent/HU210877A9/hu
Priority to GR980400270T priority patent/GR3026279T3/el
Priority to HK98102807.2A priority patent/HK1003830B/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB898927981A 1989-12-11 1989-12-11 Carbamoyl derivative Pending GB8927981D0 (en)

Priority Applications (39)

Application Number Priority Date Filing Date Title
GB898927981A GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative
DE69032083T DE69032083T2 (de) 1989-12-11 1990-12-10 Carbamoylderivate
PL90304868A PL167449B1 (pl) 1989-12-11 1990-12-10 Sposób wytwarzania nowych pochodnych karbamoilowych PL PL PL
BG093426A BG60015B2 (bg) 1989-12-11 1990-12-10 Метод за получаване на 3-метокси-4-/1-метил-5- /2-метил-4,4,4-трифлуорбутилкарбамоил/индол-3- ил-метил/-n-/2-метилфенилсулфонил/бензамид
SI9012330A SI9012330A (en) 1989-12-11 1990-12-10 Carbamoyl derivatives
GB9026797A GB2238790B (en) 1989-12-11 1990-12-10 Leukotriene antagonistic carbamoyl derivatives
AT90313373T ATE163641T1 (de) 1989-12-11 1990-12-10 Carbamoylderivate
ZA909898A ZA909898B (en) 1989-12-11 1990-12-10 Carbamoyl derivatives
YU233090A YU48218B (sh) 1989-12-11 1990-12-10 Derivati karbamoila
HU908137A HU210441B (en) 1989-12-11 1990-12-10 Process for producing 5-(2-methyl-4,4,4-triflourobutylcarbamoil)-indole derivative and pharmaceutical compositions comprising the some compound
APAP/P/1990/000230A AP192A (en) 1989-12-11 1990-12-10 Carbamoyl derivatives.
AU67917/90A AU642182B2 (en) 1989-12-11 1990-12-10 5-(2-methyl-4,4,4-trifluorobutyl-carbamoyl)indole derivatives
SK6146-90A SK614690A3 (en) 1989-12-11 1990-12-10 5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)indole derivatives, preparation method thereof and pharmaceutical compositions containing them
IE444890A IE904448A1 (en) 1989-12-11 1990-12-10 Carbamoyl derivatives
EP90313373A EP0432984B1 (en) 1989-12-11 1990-12-10 Carbamoyl derivatives
MYPI90002157A MY106363A (en) 1989-12-11 1990-12-10 Carbamoyl indole derivatives having leukotriene antagonists properties
CA002031897A CA2031897C (en) 1989-12-11 1990-12-10 Carbamoyl derivatives
SU04831920A RU2002740C1 (ru) 1989-12-11 1990-12-10 3-Метокси-4-[1-метил-5-(2-метил-4,4,4-трифторбутилкарбамоил)индол-3-илметил]-N-(2-метилфенилсульфонил)бензамид или его фармацевтически приемлемые соли в качестве антагонистов лейкотриена и полупродукты дл их получени
CS906146A CZ282068B6 (cs) 1989-12-11 1990-12-10 3-Methoxy-4-[1-methyl-5-(2-methyl-4,4,4-trifluorbutylkarbamoyl)indol-3-ylmethyl]-N-(2-methylfenylsulfonyl)benzamid, jeho farmaceuticky přijatelná sůl, způsob jejich přípravy a farmaceutické prostředky tyto látky obsahující
BG095502A BG50606A3 (bg) 1989-12-11 1990-12-10 Метод за получаване на 3-метокси-4-/1-метил-5-/2-метил-4,4,4- трифлуорбутилкарбамоил/индол-3-ил-метил/-n-/2-метилфенил- сулфонил/бензамид
NO905327A NO174198C (no) 1989-12-11 1990-12-10 Analogifremgangsmåte for fremst.av den terapeutisk aktive forbindelse 3-metoksy-4-(1-metyl-5-(2-metyl-4,4,4-trifluorbutylkarbamoyl)indol-3-ylmetyl)-N-(2-metylfenyl-sulfonyl)benzamid, eller et farmasöytisk akseptabelt salt derav
DK90313373T DK0432984T3 (da) 1989-12-11 1990-12-10 Carbamoylderivater
IL9662190A IL96621A (en) 1989-12-11 1990-12-10 3-Methoxy-4-(1-methyl-5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)indol-3-ylmethyl)-n-(2-methylphenylsulfonyl)benzamide and salts thereof, process for their preparation and pharmaceutical compositions containing them
RO146517A RO108562B1 (ro) 1989-12-11 1990-12-10 Derivati de carbamoil,procedee pentru prepararea acestora,compozitii farmaceutice,care ii contin si intermediari in sinteza acestora
ES90313373T ES2112832T3 (es) 1989-12-11 1990-12-10 Derivados carbamoilicos.
PL90288184A PL166516B1 (pl) 1989-12-11 1990-12-10 Sposób wytwarzania nowych pochodnych karbamollowych PL PL PL
FI906084A FI95029C (fi) 1989-12-11 1990-12-11 Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi
JP2419290A JPH0822849B2 (ja) 1989-12-11 1990-12-11 カルバモイル誘導体
PT96154A PT96154B (pt) 1989-12-11 1990-12-11 Processo para a preparacao de derivados de carbamoilo e de composicoes farmaceuticas que os contem
BR909006302A BR9006302A (pt) 1989-12-11 1990-12-11 Compostos,processo para sua preparacao e composicao farmaceutica
CN90110406A CN1025786C (zh) 1989-12-11 1990-12-11 氨基甲酰基衍生物的制备方法
KR1019900020547A KR100192999B1 (ko) 1989-12-11 1990-12-11 신규의 카르바모일 유도체, 이의 제법 및 이를 함유한 약학적 조성물
TW079110705A TW219329B (enExample) 1989-12-11 1990-12-20
US07/927,762 US5286740A (en) 1989-12-11 1992-08-10 Carbamoyl derivatives
HRP-2330/90A HRP930326B1 (en) 1989-12-11 1993-03-11 Carbamoyl derivatives
US08/137,245 US5334765A (en) 1989-12-11 1993-10-14 Carbamoyl derivatives
HU95P/P00183P HU210877A9 (en) 1989-12-11 1995-06-12 Carbamoyl derivatives
GR980400270T GR3026279T3 (en) 1989-12-11 1998-03-05 Carbamoyl derivatives
HK98102807.2A HK1003830B (en) 1989-12-11 1998-04-02 Carbamoyl derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898927981A GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative

Publications (1)

Publication Number Publication Date
GB8927981D0 true GB8927981D0 (en) 1990-02-14

Family

ID=10667774

Family Applications (2)

Application Number Title Priority Date Filing Date
GB898927981A Pending GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative
GB9026797A Revoked GB2238790B (en) 1989-12-11 1990-12-10 Leukotriene antagonistic carbamoyl derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB9026797A Revoked GB2238790B (en) 1989-12-11 1990-12-10 Leukotriene antagonistic carbamoyl derivatives

Country Status (31)

Country Link
EP (1) EP0432984B1 (enExample)
JP (1) JPH0822849B2 (enExample)
KR (1) KR100192999B1 (enExample)
CN (1) CN1025786C (enExample)
AP (1) AP192A (enExample)
AT (1) ATE163641T1 (enExample)
AU (1) AU642182B2 (enExample)
BG (2) BG60015B2 (enExample)
CA (1) CA2031897C (enExample)
CZ (1) CZ282068B6 (enExample)
DE (1) DE69032083T2 (enExample)
DK (1) DK0432984T3 (enExample)
ES (1) ES2112832T3 (enExample)
FI (1) FI95029C (enExample)
GB (2) GB8927981D0 (enExample)
GR (1) GR3026279T3 (enExample)
HR (1) HRP930326B1 (enExample)
HU (2) HU210441B (enExample)
IE (1) IE904448A1 (enExample)
IL (1) IL96621A (enExample)
MY (1) MY106363A (enExample)
NO (1) NO174198C (enExample)
PL (2) PL167449B1 (enExample)
PT (1) PT96154B (enExample)
RO (1) RO108562B1 (enExample)
RU (1) RU2002740C1 (enExample)
SI (1) SI9012330A (enExample)
SK (1) SK614690A3 (enExample)
TW (1) TW219329B (enExample)
YU (1) YU48218B (enExample)
ZA (1) ZA909898B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59103389D1 (de) * 1990-05-04 1994-12-08 Ciba Geigy Ag Substituierte Indole.
GB9020338D0 (en) * 1990-09-18 1990-10-31 Lilly Industries Ltd Pharmaceutical compounds
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
ES2050611B1 (es) * 1992-10-08 1994-12-16 Ici Plc Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
WO1996008496A1 (en) * 1994-09-16 1996-03-21 Takeda Chemical Industries, Ltd. Triazolopyridazines process and intermediates for their preparation and their use as medicaments
US7166638B2 (en) * 2003-05-27 2007-01-23 Nicox S.A. Statin derivatives
JP2008515971A (ja) * 2004-10-12 2008-05-15 デコード ジェネティクス イーエイチエフ 閉塞性動脈疾患のためのスルホンアミドぺリ置換二環式化合物
ES2395929T3 (es) * 2005-02-25 2013-02-18 Ono Pharmaceutical Co., Ltd. Compuestos de indol para tratar trastornos respiratorios

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524152A (en) * 1982-12-30 1985-06-18 Pennwalt Corporation 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure
GB8623429D0 (en) * 1985-10-17 1986-11-05 Ici America Inc Carboximide derivatives
AU609704B2 (en) * 1985-10-17 1991-05-09 Ici Americas Inc. Indole and indazole ketosulphone leukotriene antagonists
MY103259A (en) * 1987-04-15 1993-05-29 Ici America Inc Aliphatic carboxamides
GB8906032D0 (en) * 1988-04-14 1989-04-26 Ici America Inc Hetera-aliphatic carboxamides
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process

Also Published As

Publication number Publication date
GB9026797D0 (en) 1991-01-30
HK1003830A1 (en) 1998-11-06
PT96154B (pt) 1998-05-29
AU642182B2 (en) 1993-10-14
IL96621A0 (en) 1991-09-16
RO108562B1 (ro) 1994-06-30
PL288184A1 (en) 1992-04-21
FI95029C (fi) 1995-12-11
EP0432984A3 (en) 1992-04-22
KR100192999B1 (ko) 1999-06-15
CN1025786C (zh) 1994-08-31
FI95029B (fi) 1995-08-31
DE69032083D1 (de) 1998-04-09
GR3026279T3 (en) 1998-06-30
ZA909898B (en) 1991-08-28
HU210441B (en) 1995-04-28
EP0432984A2 (en) 1991-06-19
CZ614690A3 (en) 1997-05-14
SI9012330A (en) 1997-12-31
RU2002740C1 (ru) 1993-11-15
NO905327D0 (no) 1990-12-10
YU48218B (sh) 1997-08-22
FI906084A0 (fi) 1990-12-11
IL96621A (en) 1994-11-28
DE69032083T2 (de) 1998-07-16
NO174198B (no) 1993-12-20
BG60015B2 (bg) 1993-06-30
HRP930326A2 (en) 1996-06-30
JPH0770061A (ja) 1995-03-14
AP192A (en) 1992-06-30
AP9000230A0 (en) 1991-01-31
CA2031897A1 (en) 1991-06-12
GB2238790A (en) 1991-06-12
BG50606A3 (bg) 1992-09-15
HU210877A9 (en) 1995-09-28
GB2238790B (en) 1993-06-30
SK278528B6 (en) 1997-08-06
DK0432984T3 (da) 1998-11-30
NO905327L (no) 1991-06-12
EP0432984B1 (en) 1998-03-04
CZ282068B6 (cs) 1997-05-14
KR910011780A (ko) 1991-08-07
NO174198C (no) 1994-04-06
HUT56345A (en) 1991-08-28
TW219329B (enExample) 1994-01-21
CN1053604A (zh) 1991-08-07
SK614690A3 (en) 1997-08-06
ATE163641T1 (de) 1998-03-15
JPH0822849B2 (ja) 1996-03-06
PT96154A (pt) 1991-09-30
PL166516B1 (pl) 1995-05-31
AU6791790A (en) 1991-06-13
CA2031897C (en) 2001-12-18
IE904448A1 (en) 1991-06-19
ES2112832T3 (es) 1998-04-16
HRP930326B1 (en) 1998-12-31
FI906084L (fi) 1991-06-12
PL167449B1 (pl) 1995-09-30
HU908137D0 (en) 1991-06-28
MY106363A (en) 1995-05-30
YU233090A (sh) 1993-05-28

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