DE68925002T2 - Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden. - Google Patents
Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden.Info
- Publication number
- DE68925002T2 DE68925002T2 DE68925002T DE68925002T DE68925002T2 DE 68925002 T2 DE68925002 T2 DE 68925002T2 DE 68925002 T DE68925002 T DE 68925002T DE 68925002 T DE68925002 T DE 68925002T DE 68925002 T2 DE68925002 T2 DE 68925002T2
- Authority
- DE
- Germany
- Prior art keywords
- microorganisms
- production
- organic acids
- optically active
- enzymes used
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15691188 | 1988-06-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68925002D1 DE68925002D1 (de) | 1996-01-18 |
DE68925002T2 true DE68925002T2 (de) | 1996-08-29 |
Family
ID=15638079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68925002T Expired - Fee Related DE68925002T2 (de) | 1988-06-27 | 1989-06-27 | Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0348901B1 (de) |
JP (1) | JP2623345B2 (de) |
DE (1) | DE68925002T2 (de) |
DK (1) | DK314989A (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0356912A3 (de) * | 1988-08-29 | 1991-09-18 | Idemitsu Kosan Company Limited | Verfahren zur Herstellung von 2-substituierter, optisch aktiver Karbonsäure |
US5238828A (en) * | 1988-08-29 | 1993-08-24 | Idemitsu Kosan Company Limited | Method for the preparation of an optically active 2-substituted carboxylic acid |
JP2696127B2 (ja) * | 1990-03-22 | 1998-01-14 | 旭化成工業株式会社 | 光学活性な2―ヒドロキシカルボン酸の製造法 |
JP2698936B2 (ja) * | 1990-08-16 | 1998-01-19 | 日東化学工業株式会社 | R(‐)―マンデル酸誘導体の製造法 |
DE69131217T2 (de) * | 1990-03-30 | 1999-09-23 | Mitsubishi Rayon Co | Verfahren zur Herstellung von R(-)Mandelsäure und deren Derivaten |
DK161690D0 (da) * | 1990-07-05 | 1990-07-05 | Novo Nordisk As | Fremgangsmaade til fremstilling af enantiomere forbindelser |
US5242816A (en) * | 1990-07-10 | 1993-09-07 | Lonza Ltd. | Microbiological oxidation of alkyl groups in heterocycles |
JP2974737B2 (ja) * | 1990-08-16 | 1999-11-10 | 三菱レイヨン株式会社 | 光学活性乳酸の製造法 |
US5593871A (en) * | 1990-09-20 | 1997-01-14 | E. I. Du Pont De Nemours And Company | Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles |
ES2085487T3 (es) * | 1990-09-20 | 1996-06-01 | Du Pont | Un procedimiento para la preparacion de acidos 2-alcanoicos enantiomericos. |
SG48037A1 (en) * | 1990-11-14 | 1998-04-17 | Nitto Chemical Industry Co Ltd | Biology process for production-alpha-hydroxyamide or alpha-hydroxy acid |
JPH04341185A (ja) * | 1990-12-11 | 1992-11-27 | Asahi Chem Ind Co Ltd | 新規ニトリラーゼ |
JP2676568B2 (ja) * | 1991-06-26 | 1997-11-17 | 日東化学工業株式会社 | R(−)−マンデル酸およびその誘導体の製造法 |
US5258305A (en) * | 1991-09-13 | 1993-11-02 | Nitto Chemical Industry Co., Ltd. | Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi |
JP2720140B2 (ja) * | 1993-02-03 | 1998-02-25 | 日東化学工業株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
JP3218133B2 (ja) * | 1993-02-03 | 2001-10-15 | 三菱レイヨン株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
US5597716A (en) * | 1993-11-18 | 1997-01-28 | Mitsubishi Rayon Co., Ltd. | Process for producing D-lactic acid and L-lactamide |
CA2150526C (en) * | 1994-06-09 | 2005-11-15 | Andreas Kiener | Biotechnological process for the preparation of cyclic s-.alpha.-amino carboxylic acids and r-.alpha.-amino carboxamides |
JP3235934B2 (ja) | 1994-08-04 | 2001-12-04 | 三菱レイヨン株式会社 | ロドコッカス属細菌由来カナマイシン耐性遺伝子 |
ES2126313T3 (es) * | 1994-09-22 | 1999-03-16 | Rhone Poulenc Nutrition Animal | Hidrolisis enzimatica de los 4-metiltiobutironitrilos. |
FR2724931B1 (fr) * | 1994-09-22 | 1996-12-20 | Rhone Poulenc Nutrition Animal | Hydrolyse enzymatique des 4-methylthiobutyronitrile |
EP0773297B2 (de) | 1995-11-10 | 2008-04-23 | Mitsubishi Rayon Co., Ltd. | Verfahren zur Herstellung einer alpha-Hydroxy-säure oder eines alpha-Hydroxy-amids mittels Mikroorganismen |
JPH10179183A (ja) * | 1996-12-20 | 1998-07-07 | Daicel Chem Ind Ltd | カルボン酸の製造方法 |
US5866379A (en) * | 1997-01-28 | 1999-02-02 | Novus International | Enzymatic conversion of α-hydroxynitriles to the corresponding .alpha. |
DE19848129A1 (de) | 1998-10-19 | 2000-04-20 | Basf Ag | Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten |
DE60042364D1 (de) * | 1999-04-16 | 2009-07-23 | Mitsubishi Rayon Co | Neue amidasegene |
DE10010149A1 (de) * | 2000-03-03 | 2001-09-06 | Basf Ag | Nitrilase aus Rhodococcus rhodochrous NCIMB 11216 |
JP4544695B2 (ja) * | 2000-04-28 | 2010-09-15 | 旭化成ケミカルズ株式会社 | グリシンの微生物学的な製造法 |
FR2822460B1 (fr) * | 2001-03-26 | 2005-04-29 | Rhodia Chimie Sa | Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles |
JP4584242B2 (ja) | 2003-02-27 | 2010-11-17 | ビーエーエスエフ ソシエタス・ヨーロピア | 改変されたニトリラーゼおよびカルボン酸の製造方法におけるその使用 |
JP4493011B2 (ja) * | 2004-06-11 | 2010-06-30 | 三菱レイヨン株式会社 | ロドコッカス属細菌由来トリメトプリム耐性ジヒドロ葉酸還元酵素及びその遺伝子 |
GB0413322D0 (en) * | 2004-06-15 | 2004-07-14 | Avecia Ltd | Process |
JP4929700B2 (ja) * | 2005-12-15 | 2012-05-09 | 住友化学株式会社 | カルボン酸の製造法 |
JP2007295821A (ja) * | 2006-04-28 | 2007-11-15 | Asahi Kasei Chemicals Corp | 生体触媒を用いたα−ヒドロキシ酸或いはα−ヒドロキシ酸アンモニウムの製造方法 |
EP1881077A1 (de) * | 2006-07-19 | 2008-01-23 | Solvay Organics GmbH | Verfahren zur Herstellung von fluorhaltigen alpha-Hydroxycarbonsäuren |
EP2574667A1 (de) | 2011-10-02 | 2013-04-03 | Technische Universität Graz | Enzymvarianten |
CN114236024B (zh) * | 2021-12-07 | 2023-12-29 | 江苏宝众宝达药业股份有限公司 | 一种同时测定4-氟-3-硝基苯腈及其异构体含量的方法 |
CN117050922B (zh) * | 2023-10-11 | 2023-12-08 | 江苏聚庚科技股份有限公司 | 一种含氟苯腈类化合物降解菌及其在环境治理中的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1342844A (fr) * | 1961-09-16 | 1963-11-15 | Bayer Ag | Procédé de préparation d'acides phénoxyacétiques substitués, optiquement actifs |
JPS5414668B2 (de) * | 1972-09-05 | 1979-06-08 | ||
DK261685A (da) * | 1985-06-11 | 1986-12-12 | Novo Industri As | Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser |
JPS6255098A (ja) * | 1985-09-04 | 1987-03-10 | Nitto Chem Ind Co Ltd | 光学活性α−オキシ酸の製造法 |
FR2626289B1 (fr) * | 1988-01-27 | 1990-06-08 | Rhone Poulenc Sante | Procede de preparation d'acides aryl-2 alkanoiques optiquement actifs |
FR2626288B1 (de) * | 1988-01-27 | 1990-05-18 | Rhone Poulenc Sante | |
FR2631975B1 (fr) * | 1988-05-26 | 1990-11-30 | Rhone Poulenc Chimie | Procede de preparation d'acides aryloxy-2 ou arylthio-2 alkanoiques optiquement actifs |
-
1989
- 1989-06-26 JP JP1160653A patent/JP2623345B2/ja not_active Expired - Fee Related
- 1989-06-26 DK DK314989A patent/DK314989A/da not_active Application Discontinuation
- 1989-06-27 EP EP89111684A patent/EP0348901B1/de not_active Expired - Lifetime
- 1989-06-27 DE DE68925002T patent/DE68925002T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0348901A3 (de) | 1991-07-24 |
JP2623345B2 (ja) | 1997-06-25 |
EP0348901B1 (de) | 1995-12-06 |
JPH0284198A (ja) | 1990-03-26 |
DE68925002D1 (de) | 1996-01-18 |
DK314989D0 (da) | 1989-06-26 |
DK314989A (da) | 1989-12-28 |
EP0348901A2 (de) | 1990-01-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |