DE60329700D1 - Glycoproteinsynthese - Google Patents
GlycoproteinsyntheseInfo
- Publication number
- DE60329700D1 DE60329700D1 DE60329700T DE60329700T DE60329700D1 DE 60329700 D1 DE60329700 D1 DE 60329700D1 DE 60329700 T DE60329700 T DE 60329700T DE 60329700 T DE60329700 T DE 60329700T DE 60329700 D1 DE60329700 D1 DE 60329700D1
- Authority
- DE
- Germany
- Prior art keywords
- amino acid
- unnatural amino
- protein
- methods
- method involves
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41926502P | 2002-10-16 | 2002-10-16 | |
US42099002P | 2002-10-23 | 2002-10-23 | |
US44145003P | 2003-01-16 | 2003-01-16 | |
PCT/US2003/032870 WO2004035605A2 (en) | 2002-10-16 | 2003-10-15 | Glycoprotein synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60329700D1 true DE60329700D1 (en) | 2009-11-26 |
Family
ID=32110831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60329700T Expired - Lifetime DE60329700D1 (en) | 2002-10-16 | 2003-10-15 | Glycoproteinsynthese |
Country Status (14)
Country | Link |
---|---|
US (11) | US6927042B2 (de) |
EP (1) | EP1558747B1 (de) |
JP (1) | JP4752001B2 (de) |
KR (1) | KR20050073559A (de) |
AT (1) | ATE445709T1 (de) |
AU (1) | AU2003286436B2 (de) |
CA (1) | CA2500653A1 (de) |
DE (1) | DE60329700D1 (de) |
ES (1) | ES2333422T3 (de) |
HK (1) | HK1074855A1 (de) |
IL (6) | IL196906A0 (de) |
MX (1) | MXPA05003978A (de) |
SG (1) | SG160203A1 (de) |
WO (1) | WO2004035605A2 (de) |
Families Citing this family (103)
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US7618775B2 (en) * | 2003-04-17 | 2009-11-17 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
EP1636340A4 (de) | 2003-06-18 | 2009-02-11 | Scripps Research Inst | Ergänzungen zum genetischen code von unnatürlichen reaktiven aminosäuren |
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JP5657850B2 (ja) | 2003-10-14 | 2015-01-21 | ザ スクリプス リサーチ インスティテュート | 酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ |
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US20050260711A1 (en) * | 2004-03-30 | 2005-11-24 | Deepshikha Datta | Modulating pH-sensitive binding using non-natural amino acids |
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BRPI0511482A (pt) * | 2004-05-25 | 2007-12-26 | Scripps Research Inst | incorporação sìtio-especìfica de aminoácidos artificiais contendo átomos pesados em proteìnas para determinação de estrutura cristalina |
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KR20070039593A (ko) * | 2004-07-21 | 2007-04-12 | 암브룩스, 인코포레이티드 | 비천연적으로 코딩된 아미노산을 이용한 생합성 폴리펩티드 |
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PL1999259T3 (pl) | 2006-03-03 | 2015-01-30 | California Inst Of Techn | Specyficzne miejscowo wprowadzanie aminokwasów do cząsteczek |
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US7718410B2 (en) * | 2004-09-21 | 2010-05-18 | The Scripps Research Institute | In vivo incorporation of alkynyl amino acids into proteins in eubacteria |
WO2006036779A2 (en) * | 2004-09-22 | 2006-04-06 | The Scripps Research Institute | Site-specific labeling of proteins for nmr studies |
US20080064059A1 (en) * | 2004-10-20 | 2008-03-13 | Scripps Research Institute | In Vivo Site-Specific Incorporation of N-Acetyl-Galactosamine Amino Acids in Eubacteria |
BRPI0517381A (pt) * | 2004-10-27 | 2008-10-07 | Scripps Research Inst | componentes ortogonais de tradução para a incorporação in vivo de aminoácidos não naturais |
KR20080069993A (ko) * | 2005-10-12 | 2008-07-29 | 더 스크립스 리서치 인스티튜트 | 파지-디스플레이된 폴리펩티드의 선별적인 번역후 변형 |
JP5589186B2 (ja) * | 2006-03-09 | 2014-09-17 | ザ スクリプス リサーチ インスティテュート | 真正細菌宿主細胞における直交翻訳成分の発現システム |
US8217145B2 (en) * | 2006-03-16 | 2012-07-10 | The Scrips Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
WO2007139870A1 (en) * | 2006-05-23 | 2007-12-06 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
MX2009002987A (es) * | 2006-09-21 | 2009-04-28 | Scripps Research Inst | Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. |
JP2010506591A (ja) * | 2006-10-18 | 2010-03-04 | ザ スクリップス リサーチ インスティテュート | 哺乳動物細胞中の蛋白質への非天然アミノ酸の遺伝的組込み |
US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
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