DE602005019602D1 - Amorphe form einer zimtsäureamidverbindung - Google Patents

Amorphe form einer zimtsäureamidverbindung

Info

Publication number
DE602005019602D1
DE602005019602D1 DE602005019602T DE602005019602T DE602005019602D1 DE 602005019602 D1 DE602005019602 D1 DE 602005019602D1 DE 602005019602 T DE602005019602 T DE 602005019602T DE 602005019602 T DE602005019602 T DE 602005019602T DE 602005019602 D1 DE602005019602 D1 DE 602005019602D1
Authority
DE
Germany
Prior art keywords
cinema
connection
acid amid
amorphic form
amorphous object
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005019602T
Other languages
English (en)
Inventor
Ikuo Kushida
Eriko Doi
Koichi Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co Ltd filed Critical Eisai R&D Management Co Ltd
Publication of DE602005019602D1 publication Critical patent/DE602005019602D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Tires In General (AREA)
  • Materials For Medical Uses (AREA)
DE602005019602T 2004-10-26 2005-10-25 Amorphe form einer zimtsäureamidverbindung Active DE602005019602D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004310909 2004-10-26
PCT/JP2005/019626 WO2006046575A1 (ja) 2004-10-26 2005-10-25 シンナミド化合物の非晶質体

Publications (1)

Publication Number Publication Date
DE602005019602D1 true DE602005019602D1 (de) 2010-04-08

Family

ID=36227816

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005019602T Active DE602005019602D1 (de) 2004-10-26 2005-10-25 Amorphe form einer zimtsäureamidverbindung

Country Status (12)

Country Link
US (1) US7923563B2 (de)
EP (1) EP1808432B1 (de)
JP (1) JPWO2006046575A1 (de)
KR (1) KR20070083781A (de)
CN (1) CN100577657C (de)
AT (1) ATE458729T1 (de)
AU (1) AU2005297966B2 (de)
CA (1) CA2580119A1 (de)
DE (1) DE602005019602D1 (de)
ES (1) ES2338904T3 (de)
IL (1) IL182524A (de)
WO (1) WO2006046575A1 (de)

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EP2261218B1 (de) * 2004-05-26 2013-04-03 Eisai R&D Management Co., Ltd. Composé imidazole pour l'utilisation comme produit intermédiaire dans la production de composés cinnamide
ES2338904T3 (es) 2004-10-26 2010-05-13 EISAI R&D MANAGEMENT CO., LTD. Forma amorfa de compuestos de cinamida.
AU2006316005A1 (en) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. Process for production of cinnamamide derivative
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AU2007252644A1 (en) * 2006-05-19 2007-11-29 Eisai R & D Management Co., Ltd. Heterocyclic type cinnamide derivative
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US7737141B2 (en) 2006-07-28 2010-06-15 Eisai R&D Management Co., Ltd. Prodrug of cinnamide compound
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WO2008139984A1 (en) * 2007-04-26 2008-11-20 Eisai R & D Management Co., Ltd. Cinnamide compounds for dementia
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US20100317860A1 (en) * 2008-01-28 2010-12-16 Ikuo Kushida Crystalline cinnamide compounds or salts thereof
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TWI461425B (zh) 2009-02-19 2014-11-21 Janssen Pharmaceuticals Inc 作為伽瑪分泌酶調節劑之新穎經取代的苯并唑、苯并咪唑、唑并吡啶及咪唑并吡啶衍生物類
US8835482B2 (en) 2009-05-07 2014-09-16 Janssen Pharmaceuticals, Inc. Substituted indazole and aza-indazole derivatives as gamma secretase modulators
CA2778517A1 (en) 2009-07-15 2011-01-20 Janssen Pharmaceuticals, Inc. Substituted triazole and imidazole derivatives as gamma secretase modulators
ES2512840T3 (es) 2010-01-15 2014-10-24 Janssen Pharmaceuticals, Inc. Derivados de triazol bicíclicos sustituidos novedosos como moduladores de gamma-secretasa
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AU2013261023B2 (en) 2012-05-16 2016-11-24 Cellzome Limited Substituted 3, 4 - dihydro - 2H - pyrido [1, 2 -a] pyrazine - 1, 6 - dione derivatives useful for the treatment of (inter alia) Alzheimer's disease
WO2014096212A1 (en) 2012-12-20 2014-06-26 Janssen Pharmaceutica Nv NOVEL TRICYCLIC 3,4-DIHYDRO-2H-PYRIDO[1,2-α]PYRAZINE-1,6-DIONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
EP2945944B1 (de) 2013-01-17 2016-11-09 Janssen Pharmaceutica, N.V. Neuartige substituierte pyrido-piperazinon-derivate als gamma-sekretase-modulatoren
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators

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Also Published As

Publication number Publication date
ATE458729T1 (de) 2010-03-15
IL182524A (en) 2010-11-30
AU2005297966A1 (en) 2006-05-04
KR20070083781A (ko) 2007-08-24
EP1808432A1 (de) 2007-07-18
CN100577657C (zh) 2010-01-06
US7923563B2 (en) 2011-04-12
CA2580119A1 (en) 2006-05-04
EP1808432B1 (de) 2010-02-24
AU2005297966B2 (en) 2010-12-23
WO2006046575A1 (ja) 2006-05-04
US20090203916A1 (en) 2009-08-13
ES2338904T3 (es) 2010-05-13
JPWO2006046575A1 (ja) 2008-05-22
EP1808432A4 (de) 2009-05-27
CN101061107A (zh) 2007-10-24
IL182524A0 (en) 2007-09-20

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