DE602004026014D1 - Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben - Google Patents

Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben

Info

Publication number
DE602004026014D1
DE602004026014D1 DE602004026014T DE602004026014T DE602004026014D1 DE 602004026014 D1 DE602004026014 D1 DE 602004026014D1 DE 602004026014 T DE602004026014 T DE 602004026014T DE 602004026014 T DE602004026014 T DE 602004026014T DE 602004026014 D1 DE602004026014 D1 DE 602004026014D1
Authority
DE
Germany
Prior art keywords
cervical
solubilized
carcinomas
dissolved
body sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004026014T
Other languages
English (en)
Inventor
Ruediger Ridder
Anja Reichert
Matthias Herkert
Alexander Duwe
Rainer Hipfel
Peter Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche MTM Laboratories AG
Original Assignee
Roche MTM Laboratories AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche MTM Laboratories AG filed Critical Roche MTM Laboratories AG
Publication of DE602004026014D1 publication Critical patent/DE602004026014D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57411Specifically defined cancers of cervix
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
DE602004026014T 2003-08-25 2004-08-20 Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben Active DE602004026014D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03103218A EP1507148B1 (de) 2003-08-25 2003-08-25 Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben

Publications (1)

Publication Number Publication Date
DE602004026014D1 true DE602004026014D1 (de) 2010-04-29

Family

ID=33560881

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60300339T Expired - Lifetime DE60300339T2 (de) 2003-08-25 2003-08-25 Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben
DE602004026014T Active DE602004026014D1 (de) 2003-08-25 2004-08-20 Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60300339T Expired - Lifetime DE60300339T2 (de) 2003-08-25 2003-08-25 Verfahren zum Nachweis von Karzinomen in solubilisierten zervikalen Körperproben

Country Status (14)

Country Link
US (1) US7932047B2 (de)
EP (2) EP1507148B1 (de)
JP (2) JP5619336B2 (de)
CN (1) CN1836166B (de)
AT (2) ATE289685T1 (de)
AU (1) AU2004317284B2 (de)
BR (1) BRPI0414030B8 (de)
CA (1) CA2528490C (de)
DE (2) DE60300339T2 (de)
ES (1) ES2342535T3 (de)
HK (1) HK1092219A1 (de)
MX (1) MXPA05013903A (de)
RU (1) RU2405158C2 (de)
WO (2) WO2005088311A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
EP1510820B1 (de) * 2003-08-25 2010-03-17 MTM Laboratories AG Verfahren zum Nachweis von medizinisch relevanten Zuständen in gelösten LBC-Proben
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US8962262B2 (en) 2006-05-11 2015-02-24 Arbor Vita Corporation Method of protein extraction from cells
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US8859218B2 (en) * 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US9207240B2 (en) 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
JP2011511271A (ja) 2008-01-25 2011-04-07 サイトテック ラブズ リミテッド ライアビリティ カンパニー 腫瘍原性、腫瘍進行、および処置効率の査定のためのアッセイシステム
US20090204009A1 (en) * 2008-02-07 2009-08-13 Los Alamos National Security Medical device system and related methods for diagnosing abnormal medical conditions based on in-vivo optical properties of tissue
CA3117744C (en) * 2008-09-04 2022-07-19 Ventana Medical Systems, Inc. Method for prediction of the progression risk of tumors
CN102203293A (zh) * 2008-10-27 2011-09-28 奇亚根盖瑟斯堡股份有限公司 快速结果杂交捕获测定和系统
CN101487845B (zh) * 2009-02-19 2013-01-02 苏州海路生物技术有限公司 大便标本自动检测仪
CN102414327B (zh) 2009-05-01 2015-04-08 奇亚根盖瑟斯堡股份有限公司 用于在样品中检测rna剪接形式的非靶向扩增方法
CN102449479B (zh) * 2009-05-07 2015-11-25 安科健康公司 鉴别高度或≥cin2用于人乳头瘤病毒(hpv)与hpv相关癌症的早期及晚期检测、筛检和诊断
JP5819851B2 (ja) * 2010-01-08 2015-11-24 オンコヘルス コーポレーション Hpv関連の癌の治療及びスクリーニングのための細胞に基づいた高処理能力hpv免疫アッセイ
CA2787924A1 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のhpvの存在を決定および確認する方法
AU2011255638B2 (en) 2010-05-19 2016-08-25 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
US9212387B2 (en) 2010-06-17 2015-12-15 National University Corporation Okayama University Method for detection of genes targeted by microRNA
GB201014335D0 (en) * 2010-08-27 2010-10-13 Forensic Science Service Ltd Improvements in and relating to analysis
CN106620693A (zh) 2010-09-03 2017-05-10 艾伯维施特姆森特克斯有限责任公司 新型调节剂及使用方法
CN102033056B (zh) * 2010-10-14 2012-05-30 中国科学院化学研究所 抑制膜蛋白受体聚集的抗癌药物鉴定方法
AU2012220575B2 (en) 2011-02-24 2017-01-12 Qiagen Gaithersburg, Inc. Materials and methods for detection of HPV nucleic acid
ES2640532T3 (es) 2011-11-15 2017-11-03 University Of Miami Métodos para la detección de papilomavirus humano y proporcionar un pronóstico para el carcinoma de células escamosas de cabeza y cuello
RU2508542C1 (ru) * 2012-07-16 2014-02-27 Полина Михайловна Шварцбурд Экспресс-способ определения риска злокачественности клеток
RU2535071C1 (ru) * 2013-04-09 2014-12-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ивановская государственная медицинская академия" Министерства здравоохранения Российской Федерации Способ диагностики недифференцированной дисплазии соединительной ткани у женщин с потерей беременности в анамнезе
AU2014296090A1 (en) * 2013-07-31 2016-02-11 University Of Miami Compositions and methods for identifying a risk of cancer in a subject
WO2015147370A1 (en) * 2014-03-28 2015-10-01 Seegene, Inc. Detection of target nucleic acid sequences using different detection temperatures
RU2558987C1 (ru) * 2014-04-21 2015-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ диагностики степени тяжести недифференцированной дисплазии соединительной ткани у женщин репродуктивного возраста
WO2016198835A1 (en) 2015-06-08 2016-12-15 Arquer Diagnostics Limited Methods and kits
CN107771285A (zh) 2015-06-08 2018-03-06 阿奎尔诊断有限公司 方法
CN106610434A (zh) * 2016-02-26 2017-05-03 弗雷米德生物医药技术(天津)有限公司 一种hpv16型e7蛋白的elisa检测试剂盒
RU2680930C2 (ru) * 2017-03-24 2019-02-28 федеральное государственное бюджетное образовательное учреждение высшего образования "Северный государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ забора материала для цитологического исследования при опухолевых заболеваниях поджелудочной железы, печени и желчевыводящих путей
CN107748265A (zh) * 2017-09-29 2018-03-02 中南大学湘雅医院 Cdc6和ki67在制备癌症放疗抵抗的诊断标记物中的应用
AU2018397736A1 (en) * 2017-12-29 2020-07-09 Vertex Pharmaceuticals Incorporated Methods of cancer treatment using an ATR inhibitor
US11230729B2 (en) 2018-04-20 2022-01-25 Inanna Diagnostics, Inc Methods and devices for obtaining cellular and DNA material from human female reproductive system
CN109781977B (zh) * 2019-01-09 2022-03-29 首都医科大学附属北京安定医院 IL15Rα以及相关膜蛋白检测试剂盒及其应用
RU2707099C1 (ru) * 2019-04-24 2019-11-22 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации Способ скрининга злокачественных опухолей органов грудной полости
MX2019005940A (es) * 2019-05-21 2019-10-11 Atso Corp Affairs S A De C V Biomarcadores relacionados a cancer.

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
EP0584264A1 (de) 1991-05-16 1994-03-02 Cold Spring Harbor Laboratory D-typ cyclin und darauf bezogene anwendungen
US5889169A (en) * 1991-05-16 1999-03-30 Cold Spring Harbor Laboratory Cell cycle regulatory protein p16 gene
DE69229960T2 (de) * 1991-12-13 2000-01-05 Bion Diagnostic Sciences Inc Agglutierungsassays und kolloide farbstoffe verwendende testsätze
US6316208B1 (en) * 1994-01-07 2001-11-13 Memorial Sloan-Kettering Cancer Center Methods for determining isolated p27 protein levels and uses thereof
US6060301A (en) * 1994-03-18 2000-05-09 Myriad Genetics, Inc. Vector containing MTS1E1β gene
AU685627B2 (en) * 1994-03-18 1998-01-22 Myriad Genetics, Inc. Germline mutations in the MTS gene and method for detecting predisposition to cancer at the MTS gene
US5989815A (en) * 1994-03-18 1999-11-23 University Of Utah Research Foundation Methods for detecting predisposition to cancer at the MTS gene
CA2164167A1 (en) 1994-12-20 1996-06-21 Izak Bahar Assay normalization method
US6033847A (en) * 1995-02-06 2000-03-07 St. Jude Children's Research Hospital InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof
US5843756A (en) * 1995-06-07 1998-12-01 Myriad Genetics, Inc. Mouse MTSI gene
US6403383B1 (en) * 1996-03-11 2002-06-11 American Bio Medica Corp. Diagnostic test kit for immunological assays of fluid samples
US5976799A (en) * 1996-03-21 1999-11-02 The Board Of Trustees Of The University Of Arkansas Early detection of ovarian carcinoma using P16 gene products
US5858683A (en) * 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
AU8403098A (en) 1997-07-15 1999-02-10 Deaconess Hospital Reagents and methods for diagnosis and prognosis of proliferative disor ders
US6090579A (en) * 1997-08-12 2000-07-18 Smithkline Beecham Corporation Human SDR2 cDNA clone
BR9814271A (pt) 1997-12-12 2001-03-20 Digene Corp Determinação de doenças relacionadas com o vìrus do papiloma humano
US20010051364A1 (en) * 1997-12-23 2001-12-13 Francis Michon Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines
US5994079A (en) * 1998-02-06 1999-11-30 Digene Corporation Direct detection of RNA mediated by reverse transcriptase lacking RNAse H function
US7399589B2 (en) * 1998-02-06 2008-07-15 Digene Corporation Immunological detection of RNA:DNA hybrids on microarrays
US6686151B1 (en) 1998-02-06 2004-02-03 Digene Corporation Immunological detection of RNA:DNA hybrids on microarrays
US6576420B1 (en) * 1998-06-23 2003-06-10 Regents Of The University Of California Method for early diagnosis of, and determination of prognosis in, cancer
DE19829473C2 (de) * 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
US7306926B2 (en) * 1998-07-01 2007-12-11 Mtm Laboratories Ag Method for detecting carcinomas in a solubilized cervical body sample
US6593084B2 (en) * 1998-10-13 2003-07-15 Robert E. Bird Carcinogen assay
WO2000031538A1 (en) * 1998-11-23 2000-06-02 Praxsys Biosystems, Inc. Improved lateral flow assays
SE515668C2 (sv) * 1999-02-22 2001-09-17 Quantovir Ab Metod och kit för tidig förutsägelse av cancer
DE10014685B4 (de) * 2000-03-24 2004-07-01 Schubert, Walter, Dr. Verfahren zur Identifizierung von zellspezifischen Zielstrukturen
GB0018140D0 (en) 2000-07-24 2000-09-13 Medical Res Council Screening for abnormalities
DE10063179A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
ITRM20010363A1 (it) * 2001-06-25 2001-09-24 Franco Castelmani Gancio adattivo applicato ad un generatore di vivrazioni sinusoidali.
EP2272988A3 (de) 2002-01-07 2011-06-15 Norchip A/S Detektionsverfahren für papillomavirus mRNA
EP1333278B1 (de) 2002-02-01 2004-03-10 MTM molecular tools in medicine Verfahren zur Prognose gastrointestinaler Tumoren
ES2215957T3 (es) * 2002-08-01 2004-10-16 Mtm Laboratories Ag Metodo para diagnostico basado en una solucion.
US7361460B2 (en) 2003-04-11 2008-04-22 Digene Corporation Approach to molecular diagnosis of human papillomavirus-related diseases

Also Published As

Publication number Publication date
DE60300339D1 (de) 2005-03-31
JP2012032412A (ja) 2012-02-16
US7932047B2 (en) 2011-04-26
CA2528490A1 (en) 2005-09-22
AU2004317284B2 (en) 2009-11-05
US20070190529A1 (en) 2007-08-16
MXPA05013903A (es) 2006-03-09
RU2405158C2 (ru) 2010-11-27
JP5619336B2 (ja) 2014-11-05
EP1507148A1 (de) 2005-02-16
BRPI0414030B1 (pt) 2017-04-04
WO2005088311A1 (en) 2005-09-22
CN1836166A (zh) 2006-09-20
CN1836166B (zh) 2010-05-26
BRPI0414030B8 (pt) 2021-07-27
EP1664788A1 (de) 2006-06-07
JP2007503208A (ja) 2007-02-22
HK1092219A1 (en) 2007-02-02
JP5677270B2 (ja) 2015-02-25
ATE461449T1 (de) 2010-04-15
DE60300339T2 (de) 2006-04-13
BRPI0414030A (pt) 2007-01-23
ES2342535T3 (es) 2010-07-08
EP1507148B1 (de) 2005-02-23
ATE289685T1 (de) 2005-03-15
RU2006101395A (ru) 2006-06-10
AU2004317284A1 (en) 2005-09-22
CA2528490C (en) 2015-11-03
WO2005084103A2 (en) 2005-09-15

Similar Documents

Publication Publication Date Title
ATE461449T1 (de) Verfahren zum nachweis von medizinisch relevanten zuständen in gelösten lbc-proben
DE59903915D1 (de) Verfahren zur frühen diagnose von carcinomen
HK1159249A1 (en) Kit for the identification of ovarian cancer protein biomarkers using proteomic techniques
ATE438853T1 (de) Diagnostische testvorrichtung
EE200300005A (et) Meetod konformse haiguse diagnoosimiseks või tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
ATE418072T1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
JOP20200216A1 (ar) تجارب للكشف عن التنكس العصبي
DE602007007775D1 (de) Reagenz für hämoglobinabbau
SI1977244T1 (sl) Razlikovanje med bakterijskim meningitisom in virusnim meningitisom
WO2006066917A3 (en) Use of asc as a marker for colorectal cancer
WO2004113574A3 (en) Methods for disease screening
WO2005040806A3 (en) Use of protein asc as a marker for breast cancer
ATE557277T1 (de) Verfahren zur diagnose von endometriose mittels tfpi-2 protein
EP1636587A4 (de) Einen für menschliches protoonkogenes protein spezifischen antikörper enthaltender diagnostischer kit für leberzirrhose
EP1988164A4 (de) Verfahren zum testen der empfindlichkeit eines soliden tumors gegenüber tyrosinkinase-inhibitor sowie testkit dafür
AU2490102A (en) Method for diagnosing a tumor in a patient determining the concentration of pibf
ATE393393T1 (de) Verwendung des proteins spee als marker für brustkrebs
WO2006112962A3 (en) Syphilis diagnostic test and kits
MXPA05006765A (es) Procedimiento de deteccion de prp utilizando un antibiotico de aminoglicosidos.
ATE483983T1 (de) Verfahren zur diagnose von chronischem stress und verwandten erkrankungen
ATE410691T1 (de) Verwendung des proteins proteasome aktivator untereinheit 3 als marker für kolorektale karzinome
EA201001340A1 (ru) Улучшенный аналитический способ для определения латентного гепатита с, его применения и соответствующий диагностический набор
WO2005040807A3 (en) Swiprosin-2 as a breast cancer marker
SG152020A1 (en) Diagnostic methods

Legal Events

Date Code Title Description
8364 No opposition during term of opposition